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Dr. Rahul Pawara (M. Pharm., Ph.D.)
Dr. Rahul Pawara (M. Pharm., Ph.D.)
R. C. Patel Institute of Pharmacy Shirpur Dist Dhule Maharashtra State India
在 rcpatelpharmacy.co.in 的电子邮件经过验证
标题
引用次数
引用次数
年份
Recent updates on third generation EGFR inhibitors and emergence of fourth generation EGFR inhibitors to combat C797S resistance
SS Harun Patel, Rahul Pawara, Azim Ansari
European Journal of Medicinal Chemistry 142, 32-47, 2017
1502017
Computational identification of 2, 4-disubstituted amino-pyrimidines as L858R/T790M-EGFR double mutant inhibitors using pharmacophore mapping, molecular docking, binding free …
R Pawara, I Ahmad, S Surana, H Patel
In Silico Pharmacology 9, 1-22, 2021
462021
The repurposed ACE2 inhibitors: SARS-CoV-2 entry blockers of Covid-19
I Ahmad, R Pawara, S Surana, H Patel
Topics in Current Chemistry 379, 1-49, 2021
452021
Design and Synthesis of Quinazolinones as EGFR inhibitors to Overcome EGFR Resistance Obstacle
HM Patel, R Pawara, A Ansari, M Noolvi, S Surana
Bioorganic & Medicinal Chemistry 25 (10), 2713-2723, 2017
452017
A structural insight of bedaquiline for the cardiotoxicity and hepatotoxicity
H Patel, R Pawara, K Pawara, F Ahmed, A Shirkhedkar, S Surana
Tuberculosis 117, 79-84, 2019
412019
Novel, selective acrylamide linked quinazolines for the treatment of double mutant EGFR-L858R/T790M Non-Small-Cell lung cancer (NSCLC)
R Pawara, I Ahmad, D Nayak, S Wagh, A Wadkar, A Ansari, S Belamkar, ...
Bioorganic Chemistry 115, 105234, 2021
402021
In silico search of triple mutant T790M/C797S allosteric inhibitors to conquer acquired resistance problem in non-small cell lung cancer (NSCLC): a combined …
HM Patel, I Ahmad, R Pawara, M Shaikh, S Surana
Journal of Biomolecular Structure and Dynamics 39 (4), 1491-1505, 2021
402021
Synthesis, molecular modeling study, and quantum-chemical-based investigations of isoindoline-1, 3-diones as antimycobacterial agents
I Ahmad, RH Pawara, RT Girase, AY Pathan, VR Jagatap, N Desai, ...
ACS omega 7 (25), 21820-21844, 2022
372022
Synthesis, molecular modelling study of the methaqualone analogues as anti-convulsant agent with improved cognition activity and minimized neurotoxicity
I Ahmad, SR Akand, M Shaikh, R Pawara, SN Manjula, H Patel
Journal of Molecular Structure 1251, 131972, 2022
342022
Emerging approaches to overcome acquired drug resistance obstacles to osimertinib in non-small-cell lung cancer
M Shaikh, Y Shinde, R Pawara, M Noolvi, S Surana, I Ahmad, H Patel
Journal of Medicinal Chemistry 65 (2), 1008-1046, 2021
342021
Optimizing cardio, hepato and phospholipidosis toxicity of the Bedaquiline by chemoinformatics and molecular modelling approach
HP R. Girase, I. Ahmad, R. Pawara
SAR and QSAR in Environmental Research, 2022
302022
Investigating the Impact of Different Acrylamide (Electrophilic Warhead) on Osimertinib's Pharmacological Spectrum by Molecular Mechanic and Quantum Mechanic Approach
SS Harun Patel, Iqrar Ahmad, Harsha Jadhav, Rahul Pawara, Deepak Lokwani
Combinatorial Chemistry & High Throughput Screening 25 (1), 149-166(18), 2022
292022
Pyridine and nitro-phenyl linked 1, 3, 4-thiadiazoles as MDR-TB inhibitors
H Patel, H Jadhav, I Ansari, R Pawara, S Surana
European Journal of Medicinal Chemistry 167, 1-9, 2019
242019
Design and synthesis of novel 2, 4-disubstituted aminopyrimidines: reversible non-covalent T790M EGFR inhibitors
H Patel, A Ansari, R Pawara, I Ansari, H Jadhav, S Surana
Journal of Receptors and Signal Transduction 38 (5-6), 393-412, 2018
232018
In-silico evidences for binding of Glucokinase activators to EGFR C797S to overcome EGFR resistance obstacle with mutant-selective allosteric inhibition
H Patel, R Pawara, S Surana
Computational biology and chemistry 74, 167-189, 2018
232018
Design and synthesis of the novel, selective WZ4002 analogue as EGFR-L858R/T790M tyrosine kinase inhibitors for targeted drug therapy in non-small-cell lung cancer (NSCLC)
R Pawara, I Ahmad, D Nayak, S Belamkar, S Surana, CN Kundu, C Patil, ...
Journal of Molecular Structure 1254, 132313, 2022
182022
In silico toxicity investigation of Methaqualone’s conjunctival, retinal, and gastrointestinal hemorrhage by molecular modelling approach
I Ahmad, R Pawara, H Patel
Molecular Simulation 48 (18), 1639-1649, 2022
172022
Exploring the anti-breast cancer potential of flavonoid analogs
V Thakor, M Poddar, S Dey, SN Manjula, SRV Madhunapantula, ...
RSC advances 6 (82), 79166-79179, 2016
152016
Triazolopyridine, a leitmotif of synthetic methods and pharmacological attributes: An extensive review
IA Popat Mohite, Deepali Nahar, Rahul Pawara, Taha Alqahtani, Sayed M. Eldin ...
Arabian Journal of Chemistry 16 (10), 105181, 2023
42023
Third Generation EGFR Inhibitors: Overcoming EGFR Resistance and Toxicity Problems
HM Patel, R Pawara, SJ Surana
Elsevier, 2018
42018
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