Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS DA Bosco, G Morfini, NM Karabacak, Y Song, F Gros-Louis, P Pasinelli, ... Nature neuroscience 13 (11), 1396-1403, 2010 | 822 | 2010 |
Axonal transport defects in neurodegenerative diseases GA Morfini, M Burns, LI Binder, NM Kanaan, N LaPointe, DA Bosco, ... Journal of Neuroscience 29 (41), 12776-12786, 2009 | 538 | 2009 |
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin‐based motility G Morfini, G Szebenyi, R Elluru, N Ratner, ST Brady The EMBO journal, 2002 | 512 | 2002 |
Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3β U Beffert, G Morfini, HH Bock, H Reyna, ST Brady, J Herz Journal of Biological Chemistry 277 (51), 49958-49964, 2002 | 364 | 2002 |
Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport G Szebenyi, GA Morfini, A Babcock, M Gould, K Selkoe, DL Stenoien, ... Neuron 40 (1), 41-52, 2003 | 363 | 2003 |
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport G Pigino, G Morfini, A Pelsman, MP Mattson, ST Brady, J Busciglio Journal of Neuroscience 23 (11), 4499-4508, 2003 | 357 | 2003 |
Basic neurochemistry: principles of molecular, cellular, and medical neurobiology S Brady, G Siegel Academic press, 2011 | 356 | 2011 |
Alterations in axonal transport motor proteins in sporadic and experimental Parkinson’s disease Y Chu, GA Morfini, LB Langhamer, Y He, ST Brady, JH Kordower Brain 135 (7), 2058-2073, 2012 | 342 | 2012 |
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases NM Kanaan, GA Morfini, NE LaPointe, GF Pigino, KR Patterson, Y Song, ... Journal of Neuroscience 31 (27), 9858-9868, 2011 | 322 | 2011 |
A novel CDK5‐dependent pathway for regulating GSK3 activity and kinesin‐driven motility in neurons G Morfini, G Szebenyi, H Brown, HC Pant, G Pigino, S DeBoer, U Beffert, ... The EMBO journal 23 (11), 2235-2245, 2004 | 320 | 2004 |
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin GA Morfini, YM You, SL Pollema, A Kaminska, K Liu, K Yoshioka, ... Nature neuroscience 12 (7), 864-871, 2009 | 294 | 2009 |
The amino terminus of tau inhibits kinesin‐dependent axonal transport: implications for filament toxicity NE LaPointe, G Morfini, G Pigino, IN Gaisina, AP Kozikowski, LI Binder, ... Journal of neuroscience research 87 (2), 440-451, 2009 | 290 | 2009 |
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta G Pigino, G Morfini, Y Atagi, A Deshpande, C Yu, L Jungbauer, M LaDu, ... Proceedings of the National Academy of Sciences 106 (14), 5907-5912, 2009 | 274 | 2009 |
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited O Lazarov, GA Morfini, EB Lee, MH Farah, A Szodorai, SR DeBoer, ... Journal of Neuroscience 25 (9), 2386-2395, 2005 | 273 | 2005 |
Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth G Paglini, G Pigino, P Kunda, G Morfini, R Maccioni, S Quiroga, A Ferreira, ... Journal of Neuroscience 18 (23), 9858-9869, 1998 | 244 | 1998 |
Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral … NE LaPointe, G Morfini, ST Brady, SC Feinstein, L Wilson, MA Jordan Neurotoxicology 37, 231-239, 2013 | 243 | 2013 |
JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport G Morfini, G Pigino, G Szebenyi, Y You, S Pollema, ST Brady Nature neuroscience 9 (7), 907-916, 2006 | 224 | 2006 |
Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system NM Kanaan, GF Pigino, ST Brady, O Lazarov, LI Binder, GA Morfini Experimental neurology 246, 44-53, 2013 | 220 | 2013 |
Differential vulnerability of neurons in Huntington’s disease: the role of cell type‐specific features I Han, YM You, JH Kordower, ST Brady, GA Morfini Journal of neurochemistry 113 (5), 1073-1091, 2010 | 200 | 2010 |
Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1 O Lazarov, GA Morfini, G Pigino, A Gadadhar, X Chen, J Robinson, H Ho, ... Journal of Neuroscience 27 (26), 7011-7020, 2007 | 158 | 2007 |