Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation S Kumar Expert opinion on drug metabolism & toxicology 6 (2), 115-131, 2010 | 205 | 2010 |
In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation JJ Li, B Wang, MC Kodali, C Chen, E Kim, BJ Patters, L Lan, S Kumar, ... Journal of neuroinflammation 15, 1-16, 2018 | 194 | 2018 |
Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway M Jin, A Ande, A Kumar, S Kumar Cell death & disease 4 (3), e554-e554, 2013 | 182 | 2013 |
Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems S Kumar, PSS Rao, R Earla, A Kumar Expert opinion on drug metabolism & toxicology 11 (3), 343-355, 2015 | 137 | 2015 |
Directed Evolution of Mammalian Cytochrome P450 2B1 MUTATIONS OUTSIDE OF THE ACTIVE SITE ENHANCE THE METABOLISM OF SEVERAL SUBSTRATES, INCLUDING THE ANTICANCER PRODRUGS … S Kumar, CS Chen, DJ Waxman, JR Halpert Journal of Biological Chemistry 280 (20), 19569-19575, 2005 | 127 | 2005 |
Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19 S Kumar, K Zhi, A Mukherji, K Gerth Viruses 12 (5), 486, 2020 | 115 | 2020 |
The metabolism of 4-aminobutyrate (GABA) in fungi S Kumar, NS Punekar Mycological Research 101 (4), 403-409, 1997 | 114 | 1997 |
HIV gp120-and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P 450 2E1 A Shah, S Kumar, SD Simon, DP Singh, A Kumar Cell death & disease 4 (10), e850-e850, 2013 | 107 | 2013 |
Diallyl sulfide: Potential use in novel therapeutic interventions in alcohol, drugs, and disease mediated cellular toxicity by targeting cytochrome P450 2E1. KS Rao P, Midde NM, Miller D, Chauhan S, Kumar A Curr Drug Metab. 16 (6), 486-503, 2015 | 91 | 2015 |
Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes S Kumar, M Jin, A Ande, N Sinha, PS Silverstein, A Kumar Expert opinion on drug metabolism & toxicology 8 (11), 1363-1375, 2012 | 79 | 2012 |
HIV-1 gp120 and drugs of abuse: interactions in the central nervous system P S Silverstein, A Shah, J Weemhoff, S Kumar, D P Singh, A Kumar Current HIV research 10 (5), 369-383, 2012 | 77 | 2012 |
A rational approach to re-engineer cytochrome P450 2B1 regioselectivity based on the crystal structure of cytochrome P450 2C5 S Kumar, EE Scott, H Liu, JR Halpert Journal of Biological Chemistry 278 (19), 17178-17184, 2003 | 76 | 2003 |
Effects of Cigarette Smoke Condensate on Oxidative Stress, Apoptotic Cell Death, and HIV Replication in Human Monocytic Cells KS Rao P, Ande A, Sinha N, Kumar A PLOS ONE 11 (5), e0155791, 2016 | 71 | 2016 |
Methamphetamine toxicity and its implications during HIV-1 infection PS Silverstein, A Shah, R Gupte, X Liu, RW Piepho, S Kumar, A Kumar Journal of neurovirology 17, 401-415, 2011 | 70 | 2011 |
PLGA Nanoparticle-Based Formulations to Cross the Blood–Brain Barrier for Drug Delivery: From R&D to cGMP K Zhi, B Raji, AR Nookala, MM Khan, XH Nguyen, S Sakshi, ... Pharmaceutics 13 (4), 500, 2021 | 68 | 2021 |
Effect of mild-to-moderate smoking on viral load, cytokines, oxidative stress, and cytochrome P450 enzymes in HIV-infected individuals A Ande, C McArthur, L Ayuk, C Awasom, PN Achu, A Njinda, N Sinha, ... PloS one 10 (4), e0122402, 2015 | 68 | 2015 |
Efficient high performance liquid chromatograph/ultraviolet method for determination of diclofenac and 4′-hydroxydiclofenac in rat serum L Kaphalia, BS Kaphalia, S Kumar, MF Kanz, M Treinen-Moslen Journal of Chromatography B 830 (2), 231-237, 2006 | 68 | 2006 |
Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide S Kumar, L Sun, H Liu, BK Muralidhara, JR Halpert Protein Engineering Design and Selection 19 (12), 547-554, 2006 | 67 | 2006 |
Effect of alcohol on drug efflux protein and drug metabolic enzymes in U937 macrophages M Jin, P Arya, K Patel, B Singh, PS Silverstein, HK Bhat, A Kumar, ... Alcoholism: Clinical and Experimental Research 35 (1), 132-139, 2011 | 66 | 2011 |
Metabolic fate of glutamate and evaluation of flux through the 4‐aminobutyrate (GABA) shunt in Aspergillus niger S Kumar, NS Punekar, V SatyaNarayan, KV Venkatesh Biotechnology and Bioengineering 67 (5), 575-584, 2000 | 66 | 2000 |