Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection A Bojarczuk, KA Miller, R Hotham, A Lewis, NV Ogryzko, AA Kamuyango, ... Scientific reports 6 (1), 21489, 2016 | 182 | 2016 |
Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish AAR Thompson, PM Elks, HM Marriott, S Eamsamarng, KR Higgins, ... Blood, The Journal of the American Society of Hematology 123 (3), 366-376, 2014 | 161 | 2014 |
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses P Sadiku, JA Willson, RS Dickinson, F Murphy, AJ Harris, A Lewis, ... The Journal of clinical investigation 127 (9), 3407-3420, 2017 | 89 | 2017 |
Hif-1α–induced expression of Il-1β protects against mycobacterial infection in zebrafish NV Ogryzko, A Lewis, HL Wilson, AH Meijer, SA Renshaw, PM Elks The Journal of Immunology 202 (2), 494-502, 2019 | 88 | 2019 |
Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism AAR Thompson, RS Dickinson, F Murphy, JP Thomson, HM Marriott, ... Science Immunology 2 (8), eaal2861, 2017 | 76 | 2017 |
Hypoxia Induces Macrophage tnfa Expression via Cyclooxygenase and Prostaglandin E2 in vivo A Lewis, PM Elks Frontiers in immunology 10, 2321, 2019 | 41 | 2019 |
Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression R Jones, KE McDonald, JA Willson, B Ghesquière, D Sammut, E Daniel, ... Blood, The Journal of the American Society of Hematology 127 (21), 2641-2644, 2016 | 25 | 2016 |
Hif‐1alpha stabilisation is protective against infection in zebrafish comorbid models Y Schild, A Mohamed, EJ Wootton, A Lewis, PM Elks The FEBS Journal 287 (18), 3925-3943, 2020 | 24 | 2020 |
Heterogeneity in the responses of human lung mast cells to stem cell factor PTP A. Lewis, J. Wan, B. Baotham, P.N. Monk, S.K. Suvarna Clinical & Experimental Allergy 43, 50-59, 2012 | 22* | 2012 |
If it’s not one thing, HIF’s another: immunoregulation by hypoxia inducible factors in disease FR Hammond, A Lewis, PM Elks The FEBS Journal 287 (18), 3907-3916, 2020 | 14 | 2020 |
Recovery from desensitization of IgE‐dependent responses in human lung mast cells A Lewis, DW MacGlashan Jr, SK Suvarna, PT Peachell Clinical & Experimental Allergy 47 (8), 1022-1031, 2017 | 13 | 2017 |
Mycophenolate mofetil increases susceptibility to opportunistic fungal infection independent of lymphocytes RH Gibson, RJ Evans, R Hotham, A Bojarczuk, A Lewis, E Bielska, ... BioRxiv, 131540, 2017 | 12 | 2017 |
Freeze‐and‐thaw‐disrupted tumour cells impair the responsiveness of DC to TLR stimulation I Tirapu, A Lewis, M Kreutz, H McLinden, SS Diebold European journal of immunology 38 (10), 2740-2750, 2008 | 9 | 2008 |
An arginase 2 promoter transgenic line illuminates immune cell polarisation in zebrafish FR Hammond, A Lewis, ZC Speirs, HE Anderson, T Sipka, LG Williams, ... Disease Models & Mechanisms 16 (6), dmm049966, 2023 | 6 | 2023 |
Oncogenic RAS drives rapid onset cellular plasticity and elicits a tumour-promoting neutrophil response at the inception of preneoplastic development AM Elliot, I Ribeiro Bravo, J Astorga Johansson, E Hutton, R Cunningham, ... bioRxiv, 2023.11. 10.566547, 2023 | 1 | 2023 |
An arginase 2 promoter transgenic illuminates anti-inflammatory signalling in zebrafish FR Hammond, A Lewis, HE Anderson, LG Williams, AH Meijer, ... bioRxiv, 2022.02. 14.480079, 2022 | 1 | 2022 |
Hif-1α stabilisation polarises macrophages via cyclooxygenase/prostaglandin E2 in vivo A Lewis, PM Elks bioRxiv, 536862, 2019 | 1 | 2019 |
Tribbles1 is host protective during in vivo mycobacterial infection FR Hammond, A Lewis, G Pollara, GS Tomlinson, M Noursadeghi, ... eLife 13, e95980, 2024 | | 2024 |
DMM Outstanding Paper Prize 2023 winners: Lídia Faria, Ffion R. Hammond and Amy Lewis R Hackett Disease Models & Mechanisms 17 (5), 2024 | | 2024 |
Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function E Watts, J Willison, S Arienti, P Sadiku, P Coelho, M Sanchez-Garcia, ... Wellcome Open Research 8, 569, 2023 | | 2023 |