Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes RM Waterhouse, EV Kriventseva, S Meister, Z Xi, KS Alvarez, ... science 316 (5832), 1738-1743, 2007 | 690 | 2007 |
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease P Ligoxygakis, N Pelte, JA Hoffmann, JM Reichhart Science 297 (5578), 114-116, 2002 | 450 | 2002 |
A serpin mutant links Toll activation to melanization in the host defence of Drosophila P Ligoxygakis, N Pelte, C Ji, V Leclerc, B Duvic, M Belvin, H Jiang, ... The EMBO journal, 2002 | 335 | 2002 |
Drosophila as a model system to unravel the layers of innate immunity to infection I Kounatidis, P Ligoxygakis Open biology 2 (5), 120075, 2012 | 243 | 2012 |
Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during … JF de Celis, J Celis, P Ligoxygakis, A Preiss, C Delidakis, S Bray Development 122 (9), 2719-2728, 1996 | 201 | 1996 |
NF-κB immunity in the brain determines fly lifespan in healthy aging and age-related neurodegeneration I Kounatidis, S Chtarbanova, Y Cao, M Hayne, D Jayanth, B Ganetzky, ... Cell reports 19 (4), 836-848, 2017 | 176 | 2017 |
Prophenoloxidase activation is not required for survival to microbial infections in Drosophila V Leclerc, N Pelte, LE Chamy, C Martinelli, P Ligoxygakis, JA Hoffmann, ... EMBO reports 7 (2), 231-235, 2006 | 176 | 2006 |
Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes AKH Shia, M Glittenberg, G Thompson, AN Weber, JM Reichhart, ... Journal of cell science 122 (24), 4505-4515, 2009 | 169 | 2009 |
Sensing of Gram‐positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP‐SA L Wang, ANR Weber, ML Atilano, SR Filipe, NJ Gay, P Ligoxygakis The EMBO journal 25 (20), 5005-5014, 2006 | 147 | 2006 |
A subset of Notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex P Ligoxygakis, SY Yu, C Delidakis, NE Baker Development 125 (15), 2893-2900, 1998 | 146 | 1998 |
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway SR Filipe, A Tomasz, P Ligoxygakis EMBO reports 6 (4), 327-333, 2005 | 137 | 2005 |
Drosophila as a model to study the role of blood cells in inflammation, innate immunity and cancer L Wang, I Kounatidis, P Ligoxygakis Frontiers in cellular and infection microbiology 3, 113, 2014 | 120 | 2014 |
Pathogen recognition and signalling in the Drosophila innate immune response L Wang, P Ligoxygakis Immunobiology 211 (4), 251-261, 2006 | 120 | 2006 |
A serpin regulates dorsal-ventral axis formation in the Drosophila embryo P Ligoxygakis, S Roth, JM Reichhart Current biology 13 (23), 2097-2102, 2003 | 112 | 2003 |
Staphylococcus aureus Survives with a Minimal Peptidoglycan Synthesis Machine but Sacrifices Virulence and Antibiotic Resistance P Reed, ML Atilano, R Alves, E Hoiczyk, X Sher, NT Reichmann, ... Plos pathogens 11 (5), e1004891, 2015 | 107 | 2015 |
Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila P Ligoxygakis, P Bulet, JM Reichhart EMBO reports 3 (7), 666-673, 2002 | 88 | 2002 |
Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans MT Glittenberg, I Kounatidis, D Christensen, M Kostov, S Kimber, ... Disease models & mechanisms 4 (4), 515-525, 2011 | 81 | 2011 |
Antimicrobial defences in Drosophila: the story so far S Naitza, P Ligoxygakis Molecular immunology 40 (12), 887-896, 2004 | 80 | 2004 |
A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense T Tsichritzis, PC Gaentzsch, S Kosmidis, AE Brown, EM Skoulakis, ... Oxford University Press for The Company of Biologists Limited 134 (14), 2605 …, 2007 | 78 | 2007 |
A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus L Hepburn, TK Prajsnar, C Klapholz, P Moreno, CA Loynes, NV Ogryzko, ... Science 346 (6209), 641-646, 2014 | 74 | 2014 |