Antiphospholipid antibodies induce a pro‐inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway MJ Mulla, JJ Brosens, LW Chamley, I Giles, C Pericleous, A Rahman, ... American Journal of Reproductive Immunology 62 (2), 96-111, 2009 | 258 | 2009 |
Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human β2‐glycoprotein I: Mutation studies including residues R39 to R43 Y Ioannou, C Pericleous, I Giles, DS Latchman, DA Isenberg, A Rahman Arthritis & Rheumatism 56 (1), 280-290, 2007 | 181 | 2007 |
In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of β2-glycoprotein I: proof of concept Y Ioannou, ZR Penabad, C Pericleous, I Giles, E Papalardo, G Vargas, ... Journal of thrombosis and haemostasis 7 (5), 833-842, 2009 | 141 | 2009 |
The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS T McDonnell, C Wincup, I Buchholz, C Pericleous, I Giles, V Ripoll, ... Blood reviews 39, 100610, 2020 | 127 | 2020 |
Novel assays of thrombogenic pathogenicity in the antiphospholipid syndrome based on the detection of molecular oxidative modification of the major autoantigen β2‐glycoprotein I Y Ioannou, JY Zhang, M Qi, L Gao, JC Qi, DM Yu, H Lau, AD Sturgess, ... Arthritis & Rheumatism 63 (9), 2774-2782, 2011 | 123 | 2011 |
Modulation of trophoblast angiogenic factor secretion by antiphospholipid antibodies is not reversed by heparin TY Carroll, MJ Mulla, CS Han, JJ Brosens, LW Chamley, I Giles, ... American Journal of Reproductive Immunology 66 (4), 286-296, 2011 | 96 | 2011 |
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways A Lambrianides, CJ Carroll, SS Pierangeli, C Pericleous, W Branch, ... The Journal of Immunology 184 (12), 6622-6628, 2010 | 95 | 2010 |
Measuring IgA anti-β2-glycoprotein I and IgG/IgA anti-domain I antibodies adds value to current serological assays for the antiphospholipid syndrome C Pericleous, I Ferreira, O Borghi, F Pregnolato, T McDonnell, ... PLoS one 11 (6), e0156407, 2016 | 83 | 2016 |
Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β 2 -glycoprotein I in a mouse model … C Pericleous, P Ruiz-Limon, Z Romay-Penabad, AC Marín, ... Rheumatology 54 (4), 722-727, 2015 | 77 | 2015 |
Prevalence and thrombotic risk assessment of anti-β2 glycoprotein I domain I antibodies: a systematic review M Radin, I Cecchi, D Roccatello, PL Meroni, S Sciascia Seminars in thrombosis and hemostasis 44 (05), 466-474, 2018 | 63 | 2018 |
Are endothelial microparticles potential markers of vascular dysfunction in the antiphospholipid syndrome? C Pericleous, I Giles, A Rahman Lupus 18 (8), 671-675, 2009 | 53 | 2009 |
Purified IgG from patients with obstetric but not IgG from non‐obstetric antiphospholipid syndrome inhibit trophoblast invasion K Poulton, VM Ripoll, C Pericleous, PL Meroni, M Gerosa, Y Ioannou, ... American Journal of Reproductive Immunology 73 (5), 390-401, 2015 | 51 | 2015 |
Antibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with ‘seronegative’antiphospholipid syndrome L Cousins, C Pericleous, M Khamashta, ML Bertolaccini, Y Ioannou, ... Annals of the rheumatic diseases 74 (1), 317-319, 2015 | 46 | 2015 |
The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature C Peghaire, NP Dufton, M Lang, II Salles-Crawley, J Ahnström, V Kalna, ... Nature communications 10 (1), 5014, 2019 | 37 | 2019 |
Antibodies against thrombin in dengue patients contain both anti-thrombotic and pro-fibrinolytic activities YC Chuang, YS Lin, HS Liu, JR Wang, TM Yeh Thrombosis and haemostasis 110 (08), 358-365, 2013 | 36 | 2013 |
Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation L Bourke, J McCormick, V Taylor, C Pericleous, B Blanchet, ... PLoS One 10 (12), e0143771, 2015 | 35 | 2015 |
Longer duration of B cell depletion is associated with better outcome SS Dias, V Rodriguez-Garcia, H Nguyen, C Pericleous, D Isenberg Rheumatology 54 (10), 1876-1881, 2015 | 34 | 2015 |
Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome C Pericleous, LA Clarke, PA Brogan, DS Latchman, DA Isenberg, ... Thrombosis and haemostasis 109 (01), 72-78, 2013 | 33 | 2013 |
Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome VM Ripoll, F Pregnolato, S Mazza, C Bodio, C Grossi, T McDonnell, ... Journal of Autoimmunity 93, 114-123, 2018 | 30 | 2018 |
Somatostatin receptor PET/MR imaging of inflammation in patients with large vessel vasculitis and atherosclerosis A Ćorović, C Wall, M Nus, D Gopalan, Y Huang, M Imaz, M Zulcinski, ... Journal of the American College of Cardiology 81 (4), 336-354, 2023 | 25 | 2023 |