Integrated engineering of β-oxidation reversal and ω-oxidation pathways for the synthesis of medium chain ω-functionalized carboxylic acids JM Clomburg, MD Blankschien, JE Vick, A Chou, S Kim, R Gonzalez Metabolic engineering 28, 202-212, 2015 | 156 | 2015 |
2-Hydroxyacyl-CoA lyase catalyzes acyloin condensation for one-carbon bioconversion A Chou, JM Clomburg, S Qian, R Gonzalez Nature chemical biology 15 (9), 900-906, 2019 | 77 | 2019 |
The role of brain-derived neurotrophic factor in bone marrow stromal cell-mediated spinal cord repair GJ Ritfeld, A Patel, A Chou, TL Novosat, DG Castillo, RAC Roos, ... Cell transplantation 24 (11), 2209-2220, 2015 | 55 | 2015 |
Escherichia coli enoyl-acyl carrier protein reductase (FabI) supports efficient operation of a functional reversal of the β-oxidation cycle JE Vick, JM Clomburg, MD Blankschien, A Chou, S Kim, R Gonzalez Applied and environmental microbiology 81 (4), 1406-1416, 2015 | 48 | 2015 |
An orthogonal metabolic framework for one-carbon utilization A Chou, SH Lee, F Zhu, JM Clomburg, R Gonzalez Nature Metabolism 3 (10), 1385-1399, 2021 | 46 | 2021 |
Engineering a highly efficient carboligase for synthetic one-carbon metabolism M Nattermann, S Burgener, P Pfister, A Chou, L Schulz, SH Lee, N Paczia, ... ACS catalysis 11 (9), 5396-5404, 2021 | 36 | 2021 |
Engineered fatty acid catabolism for fuel and chemical production S Kim, S Cheong, A Chou, R Gonzalez Current opinion in biotechnology 42, 206-215, 2016 | 28 | 2016 |
Combination of type II fatty acid biosynthesis enzymes and thiolases supports a functional β-oxidation reversal JM Clomburg, SC Contreras, A Chou, JB Siegel, R Gonzalez Metabolic engineering 45, 11-19, 2018 | 27 | 2018 |
Identification of 2-Hydroxyacyl-CoA synthases with high acyloin condensation activity for orthogonal one-carbon bioconversion SH Lee, A Chou, M Nattermann, F Zhu, JM Clomburg, N Paczia, TJ Erb, ... ACS Catalysis 13 (18), 12007-12020, 2023 | 5 | 2023 |
Metabolic flux optimization of iterative pathways through orthogonal gene expression control: Application to the β-oxidation reversal SH Lee, Y Hu, A Chou, J Chen, R Gonzalez Metabolic Engineering 82, 262-273, 2024 | 1 | 2024 |
Bioconversion of Short-Chain Hydrocarbons to Fuels and Chemicals R Gonzalez, J Clomburg, A Chou US Patent App. 18/413,954, 2024 | | 2024 |
Bioconversion of short-chain hydrocarbons to fuels and chemicals R Gonzalez, J Clomburg, C Alexander US Patent 11,913,049, 2024 | | 2024 |
Synthetic growth on one-carbon substrates R Gonzalez, C Alexander, J Clomburg, ZHU Fayin, SH Lee US Patent App. 18/042,589, 2023 | | 2023 |
Production of 2-Hydroxyacyl-CoAs and Derivatives Thereof R Gonzalez, C Alexander, J Clomburg US Patent App. 17/537,714, 2022 | | 2022 |
Biosynthesis of products from 1-carbon compounds R Gonzalez, C Alexander, J Clomburg US Patent App. 17/510,641, 2022 | | 2022 |
Biosynthesis of products from 1-carbon compounds R Gonzalez, C Alexander, J Clomburg US Patent 11,186,834, 2021 | | 2021 |
Bioconversion of Formic Acid in Escherichia coli Using a 2-Hydroxyacyl-CoA Lyase (HACL)-Based Pathway F Zhu, SH Lee, A Chou, JM Clomburg, R Gonzalez 2021 AIChE Annual Meeting, 2021 | | 2021 |
Novel Acyloin Condensation Reaction Enables One-Carbon Bioconversion A Chou, JM Clomburg, S Qian, R Gonzalez 2019 AIChE Annual Meeting, 2019 | | 2019 |
Consolidated platform for the bioconversion of single carbon feedstocks to fuels and chemicals A Chou, JM Clomburg, S Garg, R Gonzalez 2017 SIMB Annual Meeting and Exhibition, 2017 | | 2017 |
BDNF-overexpression augments bone marrow stromal cell-mediated neuroprotection in the contused rat spinal cord GJ Ritfeld, A Patel, A Chou, T Novosat, DG Castillo, R Roos, M Oudega Bone marrow stromal cell: mediated neuroprotection for spinal cord repair, 73, 2014 | | 2014 |