Inflammation and oxidative stress in an obese state and the protective effects of gallic acid PV Dludla, BB Nkambule, B Jack, Z Mkandla, T Mutize, S Silvestri, ... Nutrients 11 (1), 23, 2018 | 242 | 2018 |
The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling SC Shabalala, PV Dludla, L Mabasa, AP Kappo, AK Basson, C Pheiffer, ... Biomedicine & pharmacotherapy 131, 110785, 2020 | 122 | 2020 |
Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside PV Dludla, E Joubert, CJF Muller, J Louw, R Johnson Nutrition & metabolism 14, 1-18, 2017 | 104 | 2017 |
Aspalathin, a dihydrochalcone C‐glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis R Johnson, P Dludla, E Joubert, F February, S Mazibuko, S Ghoor, ... Molecular nutrition & food research 60 (4), 922-934, 2016 | 96 | 2016 |
A dose-dependent effect of dimethyl sulfoxide on lipid content, cell viability and oxidative stress in 3T3-L1 adipocytes PV Dludla, B Jack, A Viraragavan, C Pheiffer, R Johnson, J Louw, ... Toxicology Reports 5, 1014-1020, 2018 | 85 | 2018 |
Aspalathin from rooibos (Aspalathus linearis): a bioactive C-glucosyl dihydrochalcone with potential to target the metabolic syndrome R Johnson, D de Beer, PV Dludla, D Ferreira, CJF Muller, E Joubert Planta medica 84 (09/10), 568-583, 2018 | 83 | 2018 |
Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression PV Dludla, CJF Muller, E Joubert, J Louw, MF Essop, KB Gabuza, ... Molecules 22 (1), 129, 2017 | 80 | 2017 |
Aspalathin-enriched green rooibos extract reduces hepatic insulin resistance by modulating PI3K/AKT and AMPK pathways SE Mazibuko-Mbeje, PV Dludla, C Roux, R Johnson, S Ghoor, E Joubert, ... International journal of molecular sciences 20 (3), 633, 2019 | 77 | 2019 |
The cardioprotective effect of an aqueous extract of fermented rooibos (Aspalathus linearis) on cultured cardiomyocytes derived from diabetic rats PV Dludla, CJF Muller, J Louw, E Joubert, R Salie, AR Opoku, R Johnson Phytomedicine 21 (5), 595-601, 2014 | 77 | 2014 |
A systematic review on the functional role of Th1/Th2 cytokines in type 2 diabetes and related metabolic complications T Mahlangu, PV Dludla, TM Nyambuya, V Mxinwa, SE Mazibuko-Mbeje, ... Cytokine 126, 154892, 2020 | 76 | 2020 |
A Systematic Review on the Protective Effect of N-Acetyl Cysteine Against Diabetes-Associated Cardiovascular Complications PV Dludla, SC Dias, N Obonye, R Johnson, J Louw, BB Nkambule American Journal of Cardiovascular Drugs 18, 283-298, 2018 | 74 | 2018 |
Role of Coenzyme Q10 in Health and Disease: An Update on the Last 10 Years (2010–2020) I Cirilli, E Damiani, PV Dludla, I Hargreaves, F Marcheggiani, LE Millichap, ... Antioxidants 10 (8), 1325, 2021 | 73 | 2021 |
Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature N Muvhulawa, PV Dludla, K Ziqubu, SXH Mthembu, F Mthiyane, ... Pharmacological research 178, 106163, 2022 | 71 | 2022 |
Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress PV Dludla, SE Mabhida, K Ziqubu, BB Nkambule, SE Mazibuko-Mbeje, ... World journal of diabetes 14 (3), 130, 2023 | 62 | 2023 |
N-acetyl cysteine targets hepatic lipid accumulation to curb oxidative stress and inflammation in NAFLD: a comprehensive analysis of the literature PV Dludla, BB Nkambule, SE Mazibuko-Mbeje, TM Nyambuya, ... Antioxidants 9 (12), 1283, 2020 | 57 | 2020 |
Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: Updating the status of clinical evidence K Mokgalaboni, Y Ntamo, K Ziqubu, TM Nyambuya, BB Nkambule, ... Food & function 12 (24), 12235-12249, 2021 | 56 | 2021 |
Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications K Ziqubu, PV Dludla, E Joubert, CJF Muller, J Louw, L Tiano, ... Pharmacological Research 158, 104867, 2020 | 56 | 2020 |
The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies PV Dludla, SE Mazibuko-Mbeje, TM Nyambuya, V Mxinwa, L Tiano, ... Pharmacological research 146, 104332, 2019 | 56 | 2019 |
Drug‐induced liver injury: clinical evidence of N‐acetyl cysteine protective effects Y Ntamo, K Ziqubu, N Chellan, BB Nkambule, TM Nyambuya, ... Oxidative medicine and cellular longevity 2021 (1), 3320325, 2021 | 51 | 2021 |
The transcription profile unveils the cardio-protective effect of aspalathin against lipid toxicity in an in vitro H9c2 model R Johnson, PV Dludla, CJF Muller, B Huisamen, MF Essop, J Louw Molecules 22 (2), 219, 2017 | 51 | 2017 |