Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus H Lee, J Ren, S Nocadello, AJ Rice, I Ojeda, S Light, G Minasov, J Vargas, ... Antiviral research 139, 49-58, 2017 | 141 | 2017 |
Indole Alkaloids and Quassinoids from the Stems of Brucea mollis H Chen, J Bai, ZF Fang, SS Yu, SG Ma, S Xu, Y Li, J Qu, JH Ren, L Li, ... Journal of natural products 74 (11), 2438-2445, 2011 | 124 | 2011 |
Hit-to-Lead: hit validation and assessment KE Hevener, R Pesavento, JH Ren, H Lee, K Ratia, ME Johnson Methods in Enzymology 610, 265-309, 2018 | 46 | 2018 |
Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents H Lv, J Ren, S Ma, S Xu, J Qu, Z Liu, Q Zhou, X Chen, S Yu PLoS One 7 (1), e30342, 2012 | 45 | 2012 |
Prenylated C6–C3 compounds with molecular diversity from the roots of Illicium oligandrum SG Ma, WZ Tang, YX Liu, YC Hu, SS Yu, Y Zhang, XG Chen, J Qu, ... Phytochemistry 72 (1), 115-125, 2011 | 42 | 2011 |
Synthesis, biological evaluation, and molecular modeling of glycyrrhizin derivatives as potent high-mobility group box-1 inhibitors with anti-heart-failure activity in vivo D Du, J Yan, J Ren, H Lv, Y Li, S Xu, Y Wang, S Ma, J Qu, W Tang, Z Hu, ... Journal of Medicinal Chemistry 56 (1), 97-108, 2013 | 41 | 2013 |
(+)-Strebloside-induced cytotoxicity in ovarian cancer cells is mediated through cardiac glycoside signaling networks WL Chen, Y Ren, J Ren, C Erxleben, ME Johnson, S Gentile, ... Journal of natural products 80 (3), 659-669, 2017 | 38 | 2017 |
Na+/K+-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives Y Ren, HT Ribas, K Heath, S Wu, J Ren, P Shriwas, X Chen, ME Johnson, ... Journal of natural products 83 (3), 638-648, 2020 | 37 | 2020 |
The flavonoid apigenin is a progesterone receptor modulator with in vivo activity in the uterus M Dean, J Austin, R Jinhong, ME Johnson, DD Lantvit, JE Burdette Hormones and Cancer 9, 265-277, 2018 | 34 | 2018 |
Identification and design of novel small molecule inhibitors against MERS-CoV papain-like protease via high-throughput screening and molecular modeling H Lee, J Ren, RP Pesavento, I Ojeda, AJ Rice, H Lv, Y Kwon, ... Bioorganic & medicinal chemistry 27 (10), 1981-1989, 2019 | 31 | 2019 |
Total Syntheses of (−)-Spirooliganones A and B and Their Diastereoisomers: Absolute Stereochemistry and Inhibitory Activity against Coxsackie Virus B3 N Zhao, X Ren, J Ren, H Lü, S Ma, R Gao, Y Li, S Xu, L Li, S Yu Organic letters 17 (12), 3118-3121, 2015 | 31 | 2015 |
A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii SM Jieun Kwon, Tina Mistry, Jinhong Ren, Michael E Johnson Bioorganic & medicinal chemistry 26 (1), 65-76, 2018 | 20 | 2018 |
Four new phenolic diglycosides from the roots of Illicium oligandrum SG Ma, WZ Tang, SS Yu, XG Chen, Y Liu, WJ Wang, J Qu, S Xu, JH Ren, ... Carbohydrate research 346 (9), 1165-1168, 2011 | 20 | 2011 |
Assignment of the absolute configuration of (−)-linarinic acid by theoretical calculation and asymmetric total synthesis M Cheng, Q Li, B Lin, Y Sha, J Ren, Y He, Q Wang, H Hua, K Ruud Tetrahedron: asymmetry 17 (2), 179-183, 2006 | 20 | 2006 |
Synthesis and biological evaluation of 3-phenyl-3-aryl carboxamido propanoic acid derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26A1) D Zhao, B Sun, J Ren, F Li, S Song, X Lv, C Hao, M Cheng Bioorganic & medicinal chemistry 23 (6), 1356-1365, 2015 | 18 | 2015 |
Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper Y Ren, Q Tan, K Heath, S Wu, JR Wilson, J Ren, P Shriwas, C Yuan, ... Bioorganic & medicinal chemistry 28 (4), 115301, 2020 | 17 | 2020 |
Structure prediction and R115866 binding study of human CYP26A1: homology modelling, fold recognition, molecular docking and MD simulations JH Ren, XQ Xiong, Y Sha, MC Yan, B Lin, J Wang, YK Jing, DM Zhao, ... Molecular Simulation 34 (3), 337-346, 2008 | 15 | 2008 |
Molecular dynamics simulations of HIV‐1 protease monomer: Assembly of N‐terminus and C‐terminus into β‐sheet in water solution MC Yan, Y Sha, J Wang, XQ Xiong, JH Ren, MS Cheng Proteins: Structure, Function, and Bioinformatics 70 (3), 731-738, 2008 | 14 | 2008 |
Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus … H Lee, S Boyle-Vavra, J Ren, JA Jarusiewicz, LK Sharma, DT Hoagland, ... Antimicrobial agents and chemotherapy 63 (9), 10.1128/aac. 02593-18, 2019 | 13 | 2019 |
Stereospecific synthesis and biological evaluation of monodesmethyl metabolites of (+)-13a-(S)-deoxytylophorinine as potential antitumor agents P Yu, H Lv, C Li, J Ren, S Ma, S Xu, X Chen, S Yu Synthesis 44 (24), 3757-3764, 2012 | 13 | 2012 |