Targets of the cyclin-dependent kinase Cdk1 JA Ubersax, EL Woodbury, PN Quang, M Paraz, JD Blethrow, K Shah, ... Nature 425 (6960), 859-864, 2003 | 1171 | 2003 |
Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates K Shah, Y Liu, C Deirmengian, KM Shokat Proceedings of the National Academy of Sciences 94 (8), 3565-3570, 1997 | 557 | 1997 |
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells JR Holt, SKH Gillespie, DW Provance, K Shah, KM Shokat, DP Corey, ... Cell 108 (3), 371-381, 2002 | 381 | 2002 |
ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation H Habelhah, K Shah, L Huang, A Ostareck-Lederer, AL Burlingame, ... Nature cell biology 3 (3), 325-330, 2001 | 367 | 2001 |
Design of allele-specific inhibitors to probe protein kinase signaling AC Bishop, K Shah, Y Liu, L Witucki, C Kung, KM Shokat Current Biology 8 (5), 257-266, 1998 | 307 | 1998 |
Synthesis and anticancer activity of 5-(3-indolyl)-1, 3, 4-thiadiazoles D Kumar, NM Kumar, KH Chang, K Shah European journal of medicinal chemistry 45 (10), 4664-4668, 2010 | 282 | 2010 |
Engineering Src family protein kinases with unnatural nucleotide specificity Y Liu, K Shah, F Yang, L Witucki, KM Shokat Chemistry & biology 5 (2), 91-101, 1998 | 246 | 1998 |
Cdk5 activity in the brain–multiple paths of regulation K Shah, DK Lahiri Journal of cell science 127 (11), 2391-2400, 2014 | 224 | 2014 |
An efficient synthesis and biological study of novel indolyl-1, 3, 4-oxadiazoles as potent anticancer agents D Kumar, S Sundaree, EO Johnson, K Shah Bioorganic & Medicinal Chemistry Letters 19 (15), 4492-4494, 2009 | 221 | 2009 |
Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach AC Bishop, C Kung, K Shah, L Witucki, KM Shokat, Y Liu Journal of the American Chemical Society 121 (4), 627-631, 1999 | 218 | 1999 |
A molecular gate which controls unnatural ATP analogue recognition by the tyrosine kinase v-Src Y Liu, K Shah, F Yang, L Witucki, KM Shokat Bioorganic & medicinal chemistry 6 (8), 1219-1226, 1998 | 218 | 1998 |
Unnatural ligands for engineered proteins: new tools for chemical genetics A Bishop, O Buzko, S Heyeck-Dumas, I Jung, B Kraybill, Y Liu, K Shah, ... Annual review of biophysics and biomolecular structure 29 (1), 577-606, 2000 | 215 | 2000 |
A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway K Shah, KM Shokat Chemistry & biology 9 (1), 35-47, 2002 | 174 | 2002 |
Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue H Habelhah, K Shah, L Huang, AL Burlingame, KM Shokat, Z Ronai Journal of Biological Chemistry 276 (21), 18090-18095, 2001 | 169 | 2001 |
Fast adaptation in vestibular hair cells requires myosin-1c activity EA Stauffer, JD Scarborough, M Hirono, ED Miller, K Shah, JA Mercer, ... Neuron 47 (4), 541-553, 2005 | 164 | 2005 |
Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs ST Eblen, NV Kumar, K Shah, MJ Henderson, CKW Watts, KM Shokat, ... Journal of Biological Chemistry 278 (17), 14926-14935, 2003 | 157 | 2003 |
Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction KH Sun, Y De Pablo, F Vincent, K Shah Journal of neurochemistry 107 (1), 265-278, 2008 | 137 | 2008 |
Novel bis (indolyl) hydrazide–hydrazones as potent cytotoxic agents D Kumar, NM Kumar, S Ghosh, K Shah Bioorganic & medicinal chemistry letters 22 (1), 212-215, 2012 | 136 | 2012 |
c-Abl phosphorylates Dok1 to promote filopodia during cell spreading PJ Woodring, J Meisenhelder, SA Johnson, GL Zhou, J Field, K Shah, ... The Journal of cell biology 165 (4), 493-503, 2004 | 118 | 2004 |
The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42 M Das, DJ Wiley, X Chen, K Shah, F Verde Current Biology 19 (15), 1314-1319, 2009 | 108 | 2009 |