PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis H Zheng, M Shen, YL Zha, W Li, Y Wei, MA Blanco, G Ren, T Zhou, ... Cancer cell 26 (3), 358-373, 2014 | 227 | 2014 |
Tinagl1 suppresses triple-negative breast cancer progression and metastasis by simultaneously inhibiting integrin/FAK and EGFR signaling M Shen, YZ Jiang, Y Wei, B Ell, X Sheng, M Esposito, J Kang, X Hang, ... Cancer cell 35 (1), 64-80. e7, 2019 | 165 | 2019 |
Therapeutic antibody targeting tumor-and osteoblastic niche-derived Jagged1 sensitizes bone metastasis to chemotherapy H Zheng, Y Bae, S Kasimir-Bauer, R Tang, J Chen, G Ren, M Yuan, ... Cancer cell 32 (6), 731-747. e6, 2017 | 151 | 2017 |
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene-and carcinogen-induced mammary tumors L Wan, X Lu, S Yuan, Y Wei, F Guo, M Shen, M Yuan, R Chakrabarti, ... Cancer cell 26 (1), 92-105, 2014 | 128 | 2014 |
MiR-215 modulates gastric cancer cell proliferation by targeting RB1 Y Deng, Z Huang, Y Xu, J Jin, W Zhuo, C Zhang, X Zhang, M Shen, X Yan, ... Cancer letters 342 (1), 27-35, 2014 | 95 | 2014 |
Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2 W Li, M Shen, YZ Jiang, R Zhang, H Zheng, Y Wei, ZM Shao, Y Kang Genes & development 34 (19-20), 1310-1315, 2020 | 58 | 2020 |
Complex interplay between tumor microenvironment and cancer therapy M Shen, Y Kang Frontiers of Medicine 12, 426-439, 2018 | 49 | 2018 |
Tumor microenvironment shapes colorectal cancer progression, metastasis, and treatment responses J Li, D Chen, M Shen Frontiers in medicine 9, 869010, 2022 | 43 | 2022 |
Therapeutic targeting of metadherin suppresses colorectal and lung cancer progression and metastasis M Shen, S Xie, M Rowicki, S Michel, Y Wei, X Hang, L Wan, X Lu, M Yuan, ... Cancer research 81 (4), 1014-1025, 2021 | 43 | 2021 |
Structural insights into the tumor-promoting function of the MTDH-SND1 complex F Guo, L Wan, A Zheng, V Stanevich, Y Wei, KA Satyshur, M Shen, W Lee, ... Cell reports 8 (6), 1704-1713, 2014 | 38 | 2014 |
ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP H Fan, X Wang, W Li, M Shen, Y Wei, H Zheng, Y Kang Genes & Development 34 (19-20), 1359-1372, 2020 | 37 | 2020 |
Centrosomal protein FOR20 is essential for S-phase progression by recruiting Plk1 to centrosomes M Shen, Y Cai, Y Yang, X Yan, X Liu, T Zhou Cell research 23 (11), 1284-1295, 2013 | 34 | 2013 |
LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer I Pérez-Núñez, C Rozalen, JÁ Palomeque, I Sangrador, M Dalmau, ... Nature cancer 3 (3), 355-370, 2022 | 33 | 2022 |
Pharmacological disruption of the MTDH–SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer M Shen, HA Smith, Y Wei, YZ Jiang, S Zhao, N Wang, M Rowicki, Y Tang, ... Nature cancer 3 (1), 60-74, 2022 | 31 | 2022 |
Small-molecule inhibitors that disrupt the MTDH–SND1 complex suppress breast cancer progression and metastasis M Shen, Y Wei, H Kim, L Wan, YZ Jiang, X Hang, M Raba, S Remiszewski, ... Nature cancer 3 (1), 43-59, 2022 | 29 | 2022 |
Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities M Shen, Y Kang Genes & development 34 (23-24), 1577-1598, 2020 | 25 | 2020 |
Microtubule-binding protein FOR20 promotes microtubuledepolymerization and cell migration S Feng, Y Song, M Shen, S Xie, W Li, Y Lu, Y Yang, G Ou, J Zhou, F Wang, ... Cell Discovery, 17032, 2017 | 15 | 2017 |
Inhibition of cytokinesis by overexpression of NudCL that is localized to the centrosome and midbody Y Cai, Y Yang, M Shen, T Zhou Cell Research 19 (11), 1305-1308, 2009 | 13 | 2009 |
Role reversal: a pro-metastatic function of E-cadherin M Shen, Y Kang Developmental cell 51 (4), 417-419, 2019 | 11 | 2019 |
Structure-based design, optimization, and evaluation of potent stabilized peptide inhibitors disrupting MTDH and SND1 interaction H Chen, M Zhan, J Liu, Z Liu, M Shen, F Yang, Y Kang, F Yin, Z Li Journal of medicinal chemistry 65 (18), 12188-12199, 2022 | 8 | 2022 |