Targeting nuclear factor-kappa B to overcome resistance to chemotherapy P Godwin, AM Baird, S Heavey, MP Barr, KJ O’byrne, K Gately Frontiers in oncology 3, 120, 2013 | 325 | 2013 |
Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature MP Barr, SG Gray, AC Hoffmann, RA Hilger, J Thomale, JD O’Flaherty, ... PloS one 8 (1), e54193, 2013 | 322 | 2013 |
Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells GP Pidgeon, MP Barr, JH Harmey, DA Foley, DJ Bouchier-Hayes British journal of cancer 85 (2), 273-278, 2001 | 298 | 2001 |
Cancer stem cells in drug resistant lung cancer: Targeting cell surface markers and signaling pathways G Leon, L MacDonagh, SP Finn, S Cuffe, MP Barr Pharmacology & therapeutics 158, 71-90, 2016 | 196 | 2016 |
In vitro anticancer activity and in vivo biodistribution of rhenium (I) tricarbonyl aqua complexes KM Knopf, BL Murphy, SN MacMillan, JM Baskin, MP Barr, E Boros, ... Journal of the American Chemical Society 139 (40), 14302-14314, 2017 | 180 | 2017 |
A peptide corresponding to the neuropilin-1-binding site on VEGF165 induces apoptosis of neuropilin-1-expressing breast tumour cells MP Barr, AM Byrne, AM Duffy, CM Condron, M Devocelle, P Harriott, ... British journal of cancer 92 (2), 328-333, 2005 | 165 | 2005 |
Lung cancer stem cells: The root of resistance L MacDonagh, SG Gray, E Breen, S Cuffe, SP Finn, KJ O'Byrne, MP Barr Cancer letters 372 (2), 147-156, 2016 | 161 | 2016 |
The role of DNA repair pathways in cisplatin resistant lung cancer S O’Grady, SP Finn, S Cuffe, DJ Richard, KJ O’Byrne, MP Barr Cancer treatment reviews 40 (10), 1161-1170, 2014 | 160 | 2014 |
The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy JD O’Flaherty, M Barr, D Fennell, D Richard, J Reynolds, J O’Leary, ... Journal of thoracic oncology 7 (12), 1880-1890, 2012 | 156 | 2012 |
Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways Y Yan, K Jiang, P Liu, X Zhang, X Dong, J Gao, Q Liu, MP Barr, Q Zhang, ... Scientific reports 6 (1), 37052, 2016 | 114 | 2016 |
The emerging role of microRNAs in resistance to lung cancer treatments L MacDonagh, SG Gray, SP Finn, S Cuffe, KJ O’Byrne, MP Barr Cancer treatment reviews 41 (2), 160-169, 2015 | 112 | 2015 |
Vascular endothelial growth factor is an autocrine survival factor for breast tumour cells under hypoxia MP Barr, DJ Bouchier-Hayes, JJ Harmey International journal of oncology 32 (1), 41-48, 2008 | 100 | 2008 |
Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells M Circu, J Cardelli, M Barr, K O’Byrne, G Mills, H El-Osta PLoS One 12 (9), e0184922, 2017 | 86 | 2017 |
BBI608 inhibits cancer stemness and reverses cisplatin resistance in NSCLC L MacDonagh, SG Gray, E Breen, S Cuffe, SP Finn, KJ O'Byrne, MP Barr Cancer Letters 428, 117-126, 2018 | 80 | 2018 |
Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC L MacDonagh, MF Gallagher, B Ffrench, C Gasch, E Breen, SG Gray, ... Oncotarget 8 (42), 72544, 2017 | 78 | 2017 |
Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer MP Barr, SG Gray, K Gately, E Hams, PG Fallon, AM Davies, DJ Richard, ... Molecular cancer 14, 1-16, 2015 | 74 | 2015 |
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells T Ye, K Jiang, L Wei, MP Barr, Q Xu, G Zhang, C Ding, S Meng, H Piao American journal of cancer research 8 (8), 1514, 2018 | 71 | 2018 |
Oncolytic newcastle disease virus triggers cell death of lung cancer spheroids and is enhanced by pharmacological inhibition of autophagy L Hu, S Sun, T Wang, Y Li, K Jiang, G Lin, Y Ma, MP Barr, F Song, ... American journal of cancer research 5 (12), 3612, 2015 | 51 | 2015 |
Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer I Paul, AD Chacko, I Stasik, S Busacca, N Crawford, F McCoy, N McTavish, ... Cell death & disease 3 (12), e449-e449, 2012 | 43 | 2012 |
Ajuba inhibits hepatocellular carcinoma cell growth via targeting of β-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation M Liu, K Jiang, G Lin, P Liu, Y Yan, T Ye, G Yao, MP Barr, D Liang, ... Journal of Experimental & Clinical Cancer Research 37, 1-17, 2018 | 40 | 2018 |