Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis J Wei, L Long, K Yang, C Guy, S Shrestha, Z Chen, C Wu, P Vogel, ... Nature immunology 17 (3), 277-285, 2016 | 419 | 2016 |
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy J Wei, L Long, W Zheng, Y Dhungana, SA Lim, C Guy, Y Wang, YD Wang, ... Nature 576 (7787), 471-476, 2019 | 300 | 2019 |
Lipid signalling enforces functional specialization of Treg cells in tumours SA Lim, J Wei, TLM Nguyen, H Shi, W Su, G Palacios, Y Dhungana, ... Nature 591 (7849), 306-311, 2021 | 230 | 2021 |
Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling AKCHC Kai Yang, Daniel Bastardo Blanco, Geoffrey Neale, Peter Vogel, Julian ... NATURE, 2017 | 175 | 2017 |
mTOR signaling at the crossroads of environmental signals and T‐cell fate decisions H Huang, L Long, P Zhou, NM Chapman, H Chi Immunological reviews 295 (1), 15-38, 2020 | 138 | 2020 |
RACK1 suppresses gastric tumorigenesis by stabilizing the β-catenin destruction complex YZ Deng, F Yao, JJ Li, ZF Mao, PT Hu, LY Long, G Li, XD Ji, S Shi, ... Gastroenterology 142 (4), 812-823. e15, 2012 | 117 | 2012 |
Recruitment of phosphatase PP2A by RACK1 adaptor protein deactivates transcription factor IRF3 and limits type I interferon signaling L Long, Y Deng, F Yao, D Guan, Y Feng, H Jiang, X Li, P Hu, X Lu, ... Immunity 40 (4), 515-529, 2014 | 116 | 2014 |
Amino acids license kinase mTORC1 activity and Treg cell function via small G proteins Rag and Rheb H Shi, NM Chapman, J Wen, C Guy, L Long, Y Dhungana, S Rankin, ... Immunity 51 (6), 1012-1027. e7, 2019 | 96 | 2019 |
In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions H Huang, P Zhou, J Wei, L Long, H Shi, Y Dhungana, NM Chapman, G Fu, ... Cell 184 (5), 1245-1261. e21, 2021 | 83 | 2021 |
Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine G Fu, CS Guy, NM Chapman, G Palacios, J Wei, P Zhou, L Long, ... Nature 595 (7869), 724-729, 2021 | 78 | 2021 |
Sorafenib enriches epithelial cell adhesion molecule–positive tumor initiating cells and exacerbates a subtype of hepatocellular carcinoma through TSC2‐AKT cascade DX Guan, J Shi, Y Zhang, JS Zhao, LY Long, TW Chen, EB Zhang, ... Hepatology 62 (6), 1791-1803, 2015 | 64 | 2015 |
LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity Y Wang, X Du, J Wei, L Long, H Tan, C Guy, Y Dhungana, C Qian, ... Cell research 29 (5), 391-405, 2019 | 63 | 2019 |
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity L Long, J Wei, SA Lim, JL Raynor, H Shi, JP Connelly, H Wang, C Guy, ... Nature 600 (7888), 308-313, 2021 | 52 | 2021 |
Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF–mediated myelopoiesis CH Karmaus PWF, Herrada AA, Guy C, Neale G, Dhungana Y, Long L, Vogel P ... The Journal of Experimental Medicine 214 (9.), pii: jem.20161855. doi: 10 …, 2017 | 49* | 2017 |
RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex F Yao, LY Long, YZ Deng, YY Feng, GY Ying, WD Bao, G Li, DX Guan, ... Cell research 24 (3), 359-371, 2014 | 48 | 2014 |
Regnase-1 suppresses TCF-1+ precursor exhausted T-cell formation to limit CAR–T-cell responses against ALL W Zheng, J Wei, CC Zebley, LL Jones, Y Dhungana, YD Wang, J Mavuluri, ... Blood, The Journal of the American Society of Hematology 138 (2), 122-135, 2021 | 43 | 2021 |
Protein prenylation drives discrete signaling programs for the differentiation and maintenance of effector Treg cells W Su, NM Chapman, J Wei, H Zeng, Y Dhungana, H Shi, J Saravia, ... Cell metabolism 32 (6), 996-1011. e7, 2020 | 33 | 2020 |
EphB3 stimulates cell migration and metastasis in a kinase-dependent manner through Vav2-Rho GTPase axis in papillary thyroid cancer JJ Li, ZJ Sun, YM Yuan, FF Yin, YG Bian, LY Long, X Zhang, D Xie Journal of Biological Chemistry 292 (3), 1112-1121, 2017 | 22 | 2017 |
Iron overload in hereditary tyrosinemia type 1 induces liver injury through the Sp1/Tfr2/hepcidin axis WD Bao, Y Fan, YZ Deng, LY Long, J Wang, DX Guan, ZY Qian, P An, ... Journal of Hepatology 65 (1), 137-145, 2016 | 22 | 2016 |
Progenitor-like exhausted SPRY1+ CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma Z Liu, Y Zhang, N Ma, Y Yang, Y Ma, F Wang, Y Wang, J Wei, H Chen, ... Cancer Cell 41 (11), 1852-1870. e9, 2023 | 16 | 2023 |