The genetic architecture of the human cerebral cortex KL Grasby, N Jahanshad, JN Painter, L Colodro-Conde, J Bralten, ... Science 367 (6484), eaay6690, 2020 | 599 | 2020 |
Advancing the use of genome-wide association studies for drug repurposing WR Reay, MJ Cairns Nature Reviews Genetics 22 (10), 658-671, 2021 | 149 | 2021 |
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders WR Reay, DJ Kiltschewskij, MP Geaghan, JR Atkins, VJ Carr, MJ Green, ... Science advances 8 (14), eabj8969, 2022 | 48 | 2022 |
The role of the retinoids in schizophrenia: genomic and clinical perspectives WR Reay, MJ Cairns Molecular psychiatry 25 (4), 706-718, 2020 | 42 | 2020 |
Pairwise common variant meta-analyses of schizophrenia with other psychiatric disorders reveals shared and distinct gene and gene-set associations WR Reay, MJ Cairns Translational psychiatry 10 (1), 134, 2020 | 39 | 2020 |
Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype WR Reay, JR Atkins, Y Quidé, VJ Carr, MJ Green, MJ Cairns Molecular Psychiatry 25 (4), 719-731, 2020 | 39 | 2020 |
Pharmacological enrichment of polygenic risk for precision medicine in complex disorders WR Reay, JR Atkins, VJ Carr, MJ Green, MJ Cairns Scientific reports 10 (1), 879, 2020 | 38 | 2020 |
Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia MA Di Biase, MP Geaghan, WR Reay, J Seidlitz, CS Weickert, A Pébay, ... Molecular psychiatry 27 (4), 2052-2060, 2022 | 35 | 2022 |
The maternal immune activation model uncovers a role for the Arx gene in GABAergic dysfunction in schizophrenia JP Nakamura, A Schroeder, M Hudson, N Jones, B Gillespie, X Du, ... Brain, behavior, and immunity 81, 161-171, 2019 | 30 | 2019 |
Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa DM Adams, WR Reay, MP Geaghan, MJ Cairns Neuropsychopharmacology 46 (6), 1093-1102, 2021 | 20 | 2021 |
Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improve lung function WR Reay, SI El Shair, MP Geaghan, C Riveros, EG Holliday, MA McEvoy, ... Elife 10, e63115, 2021 | 15 | 2021 |
Genetics-informed precision treatment formulation in schizophrenia and bipolar disorder WR Reay, MP Geaghan, JR Atkins, VJ Carr, MJ Green, MJ Cairns The American Journal of Human Genetics 109 (9), 1620-1637, 2022 | 13 | 2022 |
Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort X Liu, SK Low, JR Atkins, JQ Wu, WR Reay, HM Cairns, MJ Green, ... Australian & New Zealand Journal of Psychiatry 54 (9), 902-908, 2020 | 12 | 2020 |
The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness WR Reay, MP Geaghan, MJ Cairns Nature Communications 13 (1), 3756, 2022 | 9 | 2022 |
The MIR137 VNTR rs58335419 Is Associated With Cognitive Impairment in Schizophrenia and Altered Cortical Morphology E Mahmoudi, JR Atkins, Y Quidé, WR Reay, HM Cairns, C Fitzsimmons, ... Schizophrenia Bulletin 47 (2), 495-504, 2021 | 9 | 2021 |
MicroRNA binding site variation is enriched in psychiatric disorders MP Geaghan, WR Reay, MJ Cairns Human Mutation 43 (12), 2153-2169, 2022 | 8 | 2022 |
Evidence of genetic overlap and causal relationships between blood-based biochemical traits and human cortical anatomy DJ Kiltschewskij, WR Reay, MJ Cairns Translational Psychiatry 12 (1), 373, 2022 | 8 | 2022 |
Pairwise genetic meta-analyses between schizophrenia and substance dependence phenotypes reveals novel association signals with pharmacological significance LA Greco, WR Reay, CV Dayas, MJ Cairns Translational Psychiatry 12 (1), 403, 2022 | 6 | 2022 |
Genetic variants for head size share genes and pathways with cancer MJ Knol, RA Poot, TE Evans, CL Satizabal, A Mishra, M Sargurupremraj, ... Cell Reports Medicine 5 (5), 2024 | 5 | 2024 |
Linking polygenic risk of schizophrenia to variation in magnetic resonance imaging brain measures: a comprehensive systematic review H Jameei, D Rakesh, A Zalesky, MJ Cairns, WR Reay, NR Wray, ... Schizophrenia bulletin 50 (1), 32-46, 2024 | 4 | 2024 |