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Annette Künkele
Annette Künkele
未知所在单位机构
在 charite.de 的电子邮件经过验证
标题
引用次数
引用次数
年份
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
RP Koche, E Rodriguez-Fos, K Helmsauer, M Burkert, IC MacArthur, ...
Nature genetics 52 (1), 29-34, 2020
2692020
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
LC Heukamp, T Thor, A Schramm, K De Preter, C Kumps, B De Wilde, ...
Science translational medicine 4 (141), 141ra91-141ra91, 2012
2062012
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis
NA Vitanza, AJ Johnson, AL Wilson, C Brown, JK Yokoyama, A Künkele, ...
Nature medicine 27 (9), 1544-1552, 2021
1972021
Functional Tuning of CARs Reveals Signaling Threshold above Which CD8+ CTL Antitumor Potency Is Attenuated due to Cell Fas–FasL-Dependent AICD
A Künkele, AJ Johnson, LS Rolczynski, CA Chang, V Hoglund, ...
Cancer immunology research 3 (4), 368-379, 2015
194*2015
The immune landscape of neuroblastoma: challenges and opportunities for novel therapeutic strategies in pediatric oncology
J Wienke, MP Dierselhuis, GAM Tytgat, A Künkele, S Nierkens, ...
European journal of cancer 144, 123-150, 2021
1462021
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells
JH Schulte, S Lindner, A Bohrer, J Maurer, K De Preter, S Lefever, ...
Oncogene 32 (8), 1059-1065, 2013
1262013
Preclinical assessment of CD171-directed CAR T-cell adoptive therapy for childhood neuroblastoma: CE7 epitope target safety and product manufacturing feasibility
A Künkele, A Taraseviciute, LS Finn, AJ Johnson, C Berger, O Finney, ...
Clinical cancer research 23 (2), 466-477, 2017
1222017
Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia
MA Weber, H Krakowski-Roosen, L Schröder, R Kinscherf, M Krix, ...
Acta Oncologica 48 (1), 116-124, 2009
1202009
Relationship of skeletal muscle perfusion measured by contrast‐enhanced ultrasonography to histologic microvascular density
MA Weber, H Krakowski-Roosen, S Delorme, H Renk, M Krix, J Millies, ...
Journal of ultrasound in medicine 25 (5), 583-591, 2006
772006
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas
A Künkele, K De Preter, L Heukamp, T Thor, KW Pajtler, W Hartmann, ...
Neuro-oncology 14 (7), 859-869, 2012
722012
Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma
V Arnhold, K Schmelz, J Proba, A Winkler, J Wünschel, J Toedling, ...
Oncotarget 9 (2), 2304, 2018
692018
Myoglobin plasma level related to muscle mass and fiber composition–a clinical marker of muscle wasting?
MA Weber, R Kinscherf, H Krakowski-Roosen, M Aulmann, H Renk, ...
Journal of molecular medicine 85, 887-896, 2007
642007
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions
K Schmelz, J Toedling, M Huska, MC Cwikla, LM Kruetzfeldt, J Proba, ...
Nature communications 12 (1), 6804, 2021
622021
CD171-and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing
L Andersch, J Radke, A Klaus, S Schwiebert, A Winkler, E Schumann, ...
BMC cancer 19, 1-17, 2019
602019
MiR‐34a deficiency accelerates medulloblastoma formation in vivo
T Thor, A Künkele, KW Pajtler, AK Wefers, H Stephan, P Mestdagh, ...
International Journal of Cancer 136 (10), 2293-2303, 2015
482015
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells
J Kath, W Du, A Pruene, T Braun, B Thommandru, R Turk, ML Sturgeon, ...
Molecular Therapy-Methods & Clinical Development 25, 311-330, 2022
462022
Long‐term follow‐up of pediatric patients receiving total body irradiation before hematopoietic stem cell transplantation and post‐transplant survival of> 2 years
A Künkele, M Engelhard, BP Hauffa, U Mellies, C Müntjes, C Hüer, ...
Pediatric blood & cancer 60 (11), 1792-1797, 2013
452013
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models
KW Pajtler, N Sadowski, S Ackermann, K Althoff, K Schönbeck, K Batzke, ...
Oncotarget 8 (4), 6730, 2017
442017
The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma
KW Pajtler, C Weingarten, T Thor, A Künkele, LC Heukamp, R Büttner, ...
Acta neuropathologica communications 1, 1-13, 2013
432013
Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
SM Reincke, N von Wardenburg, MA Homeyer, HC Kornau, G Spagni, ...
Cell 186 (23), 5084-5097. e18, 2023
392023
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