Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly (ADP-ribose) polymerase (PARP … MR Pan, HJ Hsieh, H Dai, WC Hung, K Li, G Peng, SY Lin Journal of Biological Chemistry 287 (9), 6764-6772, 2012 | 113 | 2012 |
Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection G Peng, H Dai, W Zhang, HJ Hsieh, MR Pan, YY Park, RYL Tsai, ... Cancer research 72 (11), 2802-2813, 2012 | 90 | 2012 |
Inhibition of DNA2 nuclease as a therapeutic strategy targeting replication stress in cancer cells S Kumar, X Peng, J Daley, L Yang, J Shen, N Nguyen, G Bae, H Niu, ... Oncogenesis 6 (4), e319-e319, 2017 | 64 | 2017 |
Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery HJ Hsieh, W Zhang, SH Lin, WH Yang, JZ Wang, J Shen, Y Zhang, Y Lu, ... Nature communications 9 (1), 3982, 2018 | 40 | 2018 |
Cellular responses to replication stress: Implications in cancer biology and therapy HJ Hsieh, G Peng DNA repair 49, 9-20, 2017 | 18 | 2017 |
Inhibition of DNA2 nuclease as a therapeutic strategy targeting replication stress in cancer cells. Oncogenesis 6: e319 S Kumar, X Peng, J Daley, L Yang, J Shen, N Nguyen, G Bae, H Niu, ... | 11 | 2017 |
Identifying cell cycle modulators that selectively target ARID1A deficiency using high-throughput image-based screening L Zhang, J Shen, Y Yin, Y Peng, L Wang, HJ Hsieh, Q Shen, PH Brown, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (7), 813-826, 2017 | 10 | 2017 |
Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and … B Zhang, E Wang, H Dai, J Shen, HJ Hsieh, X Lu, G Peng Journal of Biological Chemistry 289 (49), 34284-34295, 2014 | 10 | 2014 |
The mTOR Pathway Independent Function of NPRL2 in the Regulation of S-Phase DNA Damage Response CA An, Y Peng, L Wang, J Shen, W Zhao, Z Ju, HJ Hsieh, TA Yap, ... | | 2022 |
Mathematical Modeling Reveals That G2/M Checkpoint Override HJ Hsieh | | 2017 |
Mathematical Modeling Reveals That G2/M Checkpoint Override Creates A Therapeutic Vulnerability In Tsc2-Null Tumors HJ Hsieh | | 2017 |
Phosphorylation of BRCT-Repeat Inhibitor of hTERT (BRIT1) Coordinates TopBP1 Recruitment and Amplifies ATR Signaling B Zhang, E Wang, H Dai, J Shen, HJ Hsieh, X Lu, G Peng Journal of Biological Chemistry, jbc. M114. 587113, 2014 | | 2014 |