| Molecular docking as a popular tool in drug design, an in silico travel J De Ruyck, G Brysbaert, R Blossey, MF Lensink Advances and Applications in Bioinformatics and Chemistry, 1-11, 2016 | 380 | 2016 |
| 3, 6-Disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa R Frédérick, S Robert, C Charlier, J de Ruyck, J Wouters, B Pirotte, ... Journal of medicinal chemistry 48 (24), 7592-7603, 2005 | 89 | 2005 |
| The Antiadhesive Strategy in Crohn′s Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut D Alvarez Dorta, A Sivignon, T Chalopin, TI Dumych, G Roos, RO Bilyy, ... ChemBioChem 17 (10), 936-952, 2016 | 65 | 2016 |
| Towards the understanding of the absorption spectra of NAD (P) H/NAD (P)+ as a common indicator of dehydrogenase enzymatic activity J De Ruyck, M Famerée, J Wouters, EA Perpète, J Preat, D Jacquemin Chemical Physics Letters 450 (1-3), 119-122, 2007 | 56 | 2007 |
| How the second-order nonlinear optical response of the collagen triple helix appears: a theoretical investigation M de Wergifosse, J de Ruyck, B Champagne The Journal of Physical Chemistry C 118 (16), 8595-8602, 2014 | 40 | 2014 |
| Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics J de Ruyck, SC Rothman, CD Poulter, J Wouters Biochemical and biophysical research communications 338 (3), 1515-1518, 2005 | 36 | 2005 |
| Crystal Structure of Type 2 Isopentenyl Diphosphate Isomerase from Thermus thermophilus in Complex with Inorganic Pyrophosphate J De Ruyck, J Pouyez, SC Rothman, D Poulter, J Wouters Biochemistry 47 (35), 9051-9053, 2008 | 28 | 2008 |
| Signal transduction by BvgS sensor kinase: binding of modulator nicotinate affects the conformation and dynamics of the entire periplasmic moiety E Dupré, E Lesne, J Guérin, MF Lensink, A Verger, J De Ruyck, ... Journal of Biological Chemistry 290 (38), 23307-23319, 2015 | 27 | 2015 |
| Targeting dynamical binding processes in the design of non-antibiotic anti-adhesives by molecular simulation—The example of FimH EM Krammer, J De Ruyck, G Roos, J Bouckaert, MF Lensink Molecules 23 (7), 1641, 2018 | 26 | 2018 |
| Structures of C-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin J De Ruyck, MF Lensink, J Bouckaert IUCrJ 3 (3), 163-167, 2016 | 25 | 2016 |
| Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography J De Ruyck, V Durisotti, Y Oudjama, J Wouters Journal of Biological Chemistry 281 (26), 17864-17869, 2006 | 23 | 2006 |
| Analysis of the Interactions Taking Place in the Recognition Site of a Bimetallic Mg (II)− Zn (II) Enzyme, Isopentenyl Diphosphate Isomerase. A Parallel Quantum-Chemical and … N Gresh, N Audiffren, JP Piquemal, J De Ruyck, M Ledecq, J Wouters The Journal of Physical Chemistry B 114 (14), 4884-4895, 2010 | 22 | 2010 |
| Identification of Key Residues in Proteins Through Centrality Analysis and Flexibility Prediction with RINspector G Brysbaert, T Mauri, J de Ruyck, MF Lensink Current Protocols in Bioinformatics, e66, 2018 | 20 | 2018 |
| Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors J De Ruyck, C Dupont, E Lamy, V Le Moigne, C Biot, Y Guérardel, ... ChemistryOpen 9 (3), 351-365, 2020 | 19 | 2020 |
| Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes J de Ruyck, J Wouters Current Protein and Peptide Science 9 (2), 117-137, 2008 | 19 | 2008 |
| Inhibition studies on enzymes involved in isoprenoid biosynthesis. Focus on two potential drug targets: dxr and idi-2 enzymes J de Ruyck, J Wouters, CD Poulter Current enzyme inhibition 7 (2), 79-95, 2011 | 18 | 2011 |
| Physiochemical Tuning of Potent Escherichia coli Anti‐Adhesives by Microencapsulation and Methylene Homologation D Alvarez Dorta, T Chalopin, A Sivignon, J De Ruyck, TI Dumych, ... ChemMedChem 12 (12), 986-998, 2017 | 16 | 2017 |
| Molecular docking as a popular tool in drug design, an in silico travel. Adv Appl Bioinform Chem. 2016; 9: 1-11 J De Ruyck, G Brysbaert, R Blossey, MF Lensink | 16 | |
| Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells S Trouvilliez, J Cicero, R Lévêque, L Aubert, C Corbet, A Van Outryve, ... Journal of experimental & clinical cancer research 41 (1), 110, 2022 | 14 | 2022 |
| Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase from Streptococcus pneumoniae J De Ruyck, MW Janczak, SS Neti, SC Rothman, HL Schubert, ... Chembiochem 15 (10), 1452-1458, 2014 | 12 | 2014 |
Marc F. LensinkUniversity of Lille, CNRS UMR8576 UGSF在 univ-lille1.fr 的电子邮件经过验证
