| A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muñoz-Planillo, ... Nature medicine 21 (3), 248-255, 2015 | 2338 | 2015 |
| Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010 | 1431 | 2010 |
| MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition RC Coll, JR Hill, CJ Day, A Zamoshnikova, D Boucher, NL Massey, ... Nature chemical biology 15 (6), 556-559, 2019 | 693 | 2019 |
| Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity D Boucher, M Monteleone, RC Coll, KW Chen, CM Ross, JL Teo, ... Journal of Experimental Medicine 215 (3), 827-840, 2018 | 490 | 2018 |
| T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells G Arbore, EE West, R Spolski, AAB Robertson, A Klos, C Rheinheimer, ... Science 352 (6292), aad1210, 2016 | 490 | 2016 |
| The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype AA Basiorka, KL McGraw, EA Eksioglu, X Chen, J Johnson, L Zhang, ... Blood, The Journal of the American Society of Hematology 128 (25), 2960-2975, 2016 | 333 | 2016 |
| Monounsaturated fatty acid–enriched high-fat diets impede adipose NLRP3 inflammasome–mediated IL-1β secretion and insulin resistance despite obesity OM Finucane, CL Lyons, AM Murphy, CM Reynolds, R Klinger, NP Healy, ... Diabetes 64 (6), 2116-2128, 2015 | 301 | 2015 |
| NLRP3 and pyroptosis blockers for treating inflammatory diseases RC Coll, K Schroder, P Pelegrín Trends in pharmacological sciences 43 (8), 653-668, 2022 | 295 | 2022 |
| Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments M Haneklaus, LAJ O’Neill, RC Coll Current opinion in immunology 25 (1), 40-45, 2013 | 249 | 2013 |
| New insights into the regulation of signalling by toll-like receptors and nod-like receptors RC Coll, LAJ O’Neill Journal of innate immunity 2 (5), 406-421, 2010 | 176 | 2010 |
| NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma CM McKee, RC Coll Journal of Leucocyte Biology 108 (3), 937-952, 2020 | 157 | 2020 |
| The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes RC Coll, LAJ O'Neill PloS one 6 (12), e29539, 2011 | 157 | 2011 |
| The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome R Domingo-Fernández, RC Coll, J Kearney, S Breit, LAJ O'Neill Journal of Biological Chemistry 292 (29), 12077-12087, 2017 | 151 | 2017 |
| Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction CJ Greenhill, GW Jones, MA Nowell, Z Newton, AK Harvey, AN Moideen, ... Arthritis research & therapy 16, 1-10, 2014 | 111 | 2014 |
| Questions and controversies in innate immune research: what is the physiological role of NLRP3? RC Coll, LAJ O’Neill, K Schroder Cell death discovery 2 (1), 1-5, 2016 | 72 | 2016 |
| Sulfonylureas and related compounds and use of same L O'neill, R Coll, M Cooper, A Robertson, K SCHRODER | 69* | 2016 |
| Glutathione transferase omega 1 is required for the lipopolysaccharide-stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages D Menon, R Coll, PG Board Free Radical Biology and Medicine 73, 318-327, 2014 | 66 | 2014 |
| GSTO1-1 modulates metabolism in macrophages activated through the LPS and TLR4 pathway D Menon, R Coll, LAJ O'Neill, PG Board Journal of cell science 128 (10), 1982-1990, 2015 | 63 | 2015 |
| Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals JS Bezbradica, RC Coll, K Schroder Cellular & molecular immunology 14 (1), 118-126, 2017 | 57 | 2017 |
| Sulfonylureas as concomitant insulin secretagogues and NLRP3 inflammasome inhibitors JR Hill, RC Coll, N Sue, JC Reid, J Dou, CL Holley, R Pelingon, ... ChemMedChem 12 (17), 1449-1457, 2017 | 51 | 2017 |
Professor Kate SchroderClarivate Highly Cited Researcher; Lab Head, Institute for Molecular Bioscience, University of QLD在 imb.uq.edu.au 的电子邮件经过验证
