An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression M Srivastava, M Nambiar, S Sharma, SS Karki, G Goldsmith, M Hegde, ... Cell 151 (7), 1474-1487, 2012 | 418 | 2012 |
Chromosomal translocations in cancer M Nambiar, V Kari, SC Raghavan Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1786 (2), 139-152, 2008 | 234 | 2008 |
Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells CV Kavitha, M Nambiar, CSA Kumar, B Choudhary, K Muniyappa, ... Biochemical pharmacology 77 (3), 348-363, 2009 | 174 | 2009 |
How does DNA break during chromosomal translocations? M Nambiar, SC Raghavan Nucleic acids research 39 (14), 5813-5825, 2011 | 159 | 2011 |
Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma M Nambiar, G Goldsmith, BT Moorthy, MR Lieber, MV Joshi, B Choudhary, ... Nucleic acids research 39 (3), 936-948, 2011 | 135 | 2011 |
Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as potent anticancer agents SS Karki, K Panjamurthy, S Kumar, M Nambiar, SA Ramareddy, ... European journal of medicinal chemistry 46 (6), 2109-2116, 2011 | 131 | 2011 |
Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells KK Chiruvella, V Kari, B Choudhary, M Nambiar, RG Ghanta, ... FEBS letters 582 (29), 4066-4076, 2008 | 95 | 2008 |
Repression of harmful meiotic recombination in centromeric regions M Nambiar, GR Smith Seminars in cell & developmental biology 54, 188-197, 2016 | 92 | 2016 |
Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility VK Katapadi, M Nambiar, SC Raghavan Genomics 100 (2), 72-80, 2012 | 90 | 2012 |
Anti-apoptotic protein BCL2 down-regulates DNA end joining in cancer cells TS Kumar, V Kari, B Choudhary, M Nambiar, TS Akila, SC Raghavan Journal of biological chemistry 285 (42), 32657-32670, 2010 | 60 | 2010 |
G-Quadruplex Structures Formed at the HOX11 Breakpoint Region Contribute to Its Fragility during t(10;14) Translocation in T-Cell Leukemia M Nambiar, M Srivastava, V Gopalakrishnan, SK Sankaran, ... Molecular and cellular biology 33 (21), 4266-4281, 2013 | 58 | 2013 |
A novel DNA intercalator, butylamino-pyrimido [4′, 5′: 4, 5] selenolo (2, 3-b) quinoline, induces cell cycle arrest and apoptosis in leukemic cells MS Shahabuddin, M Nambiar, B Choudhary, GM Advirao, SC Raghavan Investigational new drugs 28, 35-48, 2010 | 58 | 2010 |
Autocyclized and oxidized forms of SCR 7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner SV Vartak, HA Swarup, V Gopalakrishnan, VK Gopinatha, V Ropars, ... The FEBS journal 285 (21), 3959-3976, 2018 | 45 | 2018 |
Propyl-2-(8-(3, 4-difluorobenzyl)-2′, 5′-dioxo-8-azaspiro [bicyclo [3.2. 1] octane-3, 4′-imidazolidine]-1′-yl) acetate induces apoptosis in human leukemia cells through … CV Kavitha, M Nambiar, PB Narayanaswamy, E Thomas, U Rathore, ... PLoS One 8 (7), e69103, 2013 | 43 | 2013 |
Mechanism of fragility at BCL2 gene minor breakpoint cluster region during t (14; 18) chromosomal translocation M Nambiar, SC Raghavan Journal of Biological Chemistry 287 (12), 8688-8701, 2012 | 41 | 2012 |
Chromosomal translocations among the healthy human population: implications in oncogenesis M Nambiar, SC Raghavan Cellular and Molecular Life Sciences 70, 1381-1392, 2013 | 39 | 2013 |
Pericentromere-specific cohesin complex prevents meiotic pericentric DNA double-strand breaks and lethal crossovers M Nambiar, GR Smith Molecular cell 71 (4), 540-553. e4, 2018 | 36 | 2018 |
Detection of G-quadruplex DNA using primer extension as a tool R Kumari, M Nambiar, S Shanbagh, SC Raghavan PloS one 10 (3), e0119722, 2015 | 27 | 2015 |
A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells MS Shahabuddin, M Nambiar, BT Moorthy, PL Naik, B Choudhary, ... Investigational new drugs 29, 523-533, 2011 | 24 | 2011 |
Prevalence and analysis of t (14; 18) and t (11; 14) chromosomal translocations in healthy Indian population M Nambiar, SC Raghavan Annals of hematology 89, 35-43, 2010 | 24 | 2010 |