Cause and consequence of Aβ–Lipid interactions in Alzheimer disease pathogenesis V Rangachari, DN Dean, P Rana, A Vaidya, P Ghosh Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1652-1662, 2018 | 50 | 2018 |
Strain-specific fibril propagation by an Aβ dodecamer DN Dean, PK Das, P Rana, F Burg, Y Levites, SE Morgan, P Ghosh, ... Scientific reports 7 (1), 40787, 2017 | 40 | 2017 |
pH-Dependent fibril maturation of a Pmel17 repeat domain isoform revealed by tryptophan fluorescence DN Dean, JC Lee Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (10), 961-969, 2019 | 34 | 2019 |
Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease A Kumar, KM Pate, MA Moss, DN Dean, V Rangachari PLoS One 9 (11), e111492, 2014 | 34 | 2014 |
Conformational dynamics of specific Aβ oligomers govern their ability to replicate and induce neuronal apoptosis DN Dean, KM Pate, MA Moss, V Rangachari Biochemistry 55 (15), 2238-2250, 2016 | 32 | 2016 |
Linking Parkinson's Disease and Melanoma: Interplay Between α‐Synuclein and Pmel17 Amyloid Formation DN Dean, JC Lee Movement Disorders 36 (7), 1489-1498, 2021 | 30 | 2021 |
Aqueous RAFT synthesis of glycopolymers for determination of saccharide structure and concentration effects on amyloid β aggregation PK Das, DN Dean, AL Fogel, F Liu, BA Abel, CL McCormick, ... Biomacromolecules 18 (10), 3359-3366, 2017 | 23 | 2017 |
Defining an amyloid link Between Parkinson’s disease and melanoma DN Dean, JC Lee Proceedings of the National Academy of Sciences 117 (37), 22671-22673, 2020 | 14 | 2020 |
Modulating functional amyloid formation via alternative splicing of the premelanosomal protein PMEL17 DN Dean, JC Lee Journal of Biological Chemistry 295 (21), 7544-7553, 2020 | 14 | 2020 |
Terminal alkynes as Raman probes of α‐Synuclein in solution and in cells JD Flynn, MY Gimmen, DN Dean, SM Lacy, JC Lee ChemBioChem 21 (11), 1582-1586, 2020 | 13 | 2020 |
Fatty Acid Concentration and Phase Transitions Modulate Aβ Aggregation Pathways P Rana, DN Dean, ED Steen, A Vaidya, V Rangachari, P Ghosh Scientific reports 7 (1), 10370, 2017 | 13 | 2017 |
Biophysical characteristics of lipid‐induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice J Saha, DN Dean, S Dhakal, KA Stockmal, SE Morgan, KD Dillon, ... The FASEB Journal 35 (2), 2021 | 12 | 2021 |
Propagation of an Aβ dodecamer strain involves a three-step mechanism and a key intermediate DN Dean, P Rana, RP Campbell, P Ghosh, V Rangachari Biophysical journal 114 (3), 539-549, 2018 | 11 | 2018 |
Cysteine-rich granulin-3 rapidly promotes amyloid-β fibrils in both redox states AA Bhopatkar, G Ghag, LM Wolf, DN Dean, MA Moss, V Rangachari Biochemical Journal 476 (5), 859-873, 2019 | 10 | 2019 |
Large fatty acid-derived Aβ42 oligomers form ring-like assemblies W Xi, DN Dean, KA Stockmal, SE Morgan, UHE Hansmann, V Rangachari The Journal of chemical physics 150 (7), 2019 | 10 | 2019 |
Purification and characterization of an amyloidogenic repeat domain from the functional amyloid Pmel17 DN Dean, JC Lee Protein expression and purification 187, 105944, 2021 | 7 | 2021 |
Stem mutants in the N-terminal domain of the phage P22 tailspike protein C Palmer, J Williams, D Dean, S Johnson, H Wu, BK Robertson, ... American Journal of Microbiological Research 2 (1), 1-7, 2013 | 6 | 2013 |
Observation of pH-Dependent Residual Structure in the Pmel17 Repeat Domain and the Implication for Its Amyloid Formation DL Morris, DA Nyenhuis, DN Dean, MP Strub, N Tjandra Biochemistry 62 (22), 3222-3233, 2023 | 1 | 2023 |
Monitoring kinetics of pH-dependent aggregation and disaggregation of the Pmel17 repeat domain DN Dean, JC Lee Protein Aggregation: Methods and Protocols, 79-93, 2022 | 1 | 2022 |
A Mechanistic Understanding of Self-Propagating Amyloid-β Oligomer Conformations in Alzheimer Disease DN Dean The University of Southern Mississippi, 2018 | | 2018 |