Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction L Shi, S Cui, JD Engel, O Tanabe Nature medicine 19 (3), 291-294, 2013 | 195 | 2013 |
Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated … S Cui, KE Kolodziej, N Obara, A Amaral-Psarris, J Demmers, L Shi, ... Molecular and cellular biology, 2011 | 155 | 2011 |
Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease Y Zhang, AR Sandy, J Wang, V Radojcic, GT Shan, IT Tran, A Friedman, ... Blood, The Journal of the American Society of Hematology 117 (1), 299-308, 2011 | 144 | 2011 |
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice S Cui, KC Lim, L Shi, M Lee, N Jearawiriyapaisarn, G Myers, A Campbell, ... Blood, The Journal of the American Society of Hematology 126 (3), 386-396, 2015 | 95 | 2015 |
Invertebrate trehalose-6-phosphate synthase gene: genetic architecture, biochemistry, physiological function, and potential applications B Tang, S Wang, SG Wang, HJ Wang, JY Zhang, SY Cui Frontiers in Physiology 9, 30, 2018 | 89 | 2018 |
Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease R Jagadeeswaran, BA Vazquez, M Thiruppathi, BB Ganesh, V Ibanez, ... Experimental hematology 50, 46-52, 2017 | 67 | 2017 |
Developmental transcriptome analysis of human erythropoiesis L Shi, YH Lin, MC Sierant, F Zhu, S Cui, Y Guan, MA Sartor, O Tanabe, ... Human molecular genetics 23 (17), 4528-4542, 2014 | 62 | 2014 |
The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis) A Rivers, K Vaitkus, V Ibanez, MA Ruiz, R Jagadeeswaran, ... Haematologica 101 (6), 688, 2016 | 60 | 2016 |
A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression TA Morrison, I Wilcox, HY Luo, JJ Farrell, R Kurita, Y Nakamura, ... Blood Cells, Molecules, and Diseases 69, 1-9, 2018 | 47 | 2018 |
Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes AD Campbell, S Cui, L Shi, R Urbonya, A Mathias, K Bradley, KO Bonsu, ... Proceedings of the National Academy of Sciences 108 (46), 18808-18813, 2011 | 45 | 2011 |
PGC-1 coactivator activity is required for murine erythropoiesis S Cui, O Tanabe, KC Lim, HE Xu, XE Zhou, JD Lin, L Shi, L Schmidt, ... Molecular and Cellular Biology 34 (11), 1956-1965, 2014 | 33 | 2014 |
Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease K Kato, S Cui, R Kuick, S Mineishi, E Hexner, JLM Ferrara, SG Emerson, ... Biology of Blood and Marrow Transplantation 16 (6), 751-771, 2010 | 32 | 2010 |
Reactivation of fetal hemoglobin for treating β-thalassemia and sickle cell disease S Cui, JD Engel Gene and Cell Therapies for Beta-Globinopathies, 177-202, 2017 | 26 | 2017 |
Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes S Cui, O Tanabe, M Sierant, L Shi, A Campbell, KC Lim, JD Engel Blood, The Journal of the American Society of Hematology 125 (9), 1477-1487, 2015 | 26 | 2015 |
Molecular characterization and functional distribution of N-ethylmaleimide-sensitive factor in Helicoverpa armigera SY Cui, WH Xu Peptides 27 (6), 1226-1234, 2006 | 23 | 2006 |
Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons V Ibanez, K Vaitkus, A Rivers, R Molokie, S Cui, JD Engel, J DeSimone, ... Blood, The Journal of the American Society of Hematology 129 (2), 260-263, 2017 | 21 | 2017 |
Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays AS de Medeiros, AR Wyman, MA Alaamery, C Allain, FD Ivey, L Wang, ... Cellular signalling 40, 73-80, 2017 | 18 | 2017 |
Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis CQ Le, G Myers, A Habara, N Jearawiriyapaisarn, GJ Murphy, DHK Chui, ... Blood, The Journal of the American Society of Hematology 133 (22), 2455-2459, 2019 | 15 | 2019 |
Transcriptional silencing of fetal hemoglobin expression by NonO X Li, M Chen, B Liu, P Lu, X Lv, X Zhao, S Cui, P Xu, Y Nakamura, ... Nucleic acids research 49 (17), 9711-9723, 2021 | 10 | 2021 |
Effects of hydroxyurea on F-cells in sickle cell disease and potential impact of a second fetal globin inducer D Yan, S J, N M, F AD, O P, R A, O O, N X, N S, M D, S Cui, T R, S M, P S Am J Hematol. 92 (1), E10-E11, 2017 | 9 | 2017 |