Analysis of optimality in natural and perturbed metabolic networks D Segre, D Vitkup, GM Church Proceedings of the national academy of sciences 99 (23), 15112-15117, 2002 | 1637 | 2002 |
Emergent simplicity in microbial community assembly JE Goldford, N Lu, D Bajić, S Estrela, M Tikhonov, A Sanchez-Gorostiaga, ... Science 361 (6401), 469-474, 2018 | 783 | 2018 |
Modular epistasis in yeast metabolism D Segre, A DeLuna, GM Church, R Kishony Nature genetics 37 (1), 77-83, 2005 | 717 | 2005 |
The lipid world D Segré, D Ben-Eli, DW Deamer, D Lancet Origins of Life and Evolution of the Biosphere 31, 119-145, 2001 | 700 | 2001 |
The effect of oxygen on biochemical networks and the evolution of complex life J Raymond, D Segrè Science 311 (5768), 1764-1767, 2006 | 546 | 2006 |
Diminishing returns epistasis among beneficial mutations decelerates adaptation HH Chou, HC Chiu, NF Delaney, D Segrè, CJ Marx Science 332 (6034), 1190-1192, 2011 | 545 | 2011 |
Metabolic resource allocation in individual microbes determines ecosystem interactions and spatial dynamics WR Harcombe, WJ Riehl, I Dukovski, BR Granger, A Betts, AH Lang, ... Cell reports 7 (4), 1104-1115, 2014 | 512 | 2014 |
Deep sequencing of the oral microbiome reveals signatures of periodontal disease B Liu, LL Faller, N Klitgord, V Mazumdar, M Ghodsi, DD Sommer, ... PloS one 7 (6), e37919, 2012 | 476 | 2012 |
Compositional genomes: prebiotic information transfer in mutually catalytic noncovalent assemblies D Segré, D Ben-Eli, D Lancet Proceedings of the National Academy of Sciences 97 (8), 4112-4117, 2000 | 391 | 2000 |
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells BM Maoz, A Herland, EA FitzGerald, T Grevesse, C Vidoudez, ... Nature biotechnology 36 (9), 865-874, 2018 | 377 | 2018 |
Environments that induce synthetic microbial ecosystems N Klitgord, D Segrè PLoS computational biology 6 (11), e1001002, 2010 | 372 | 2010 |
Costless metabolic secretions as drivers of interspecies interactions in microbial ecosystems AR Pacheco, M Moel, D Segrè Nature communications 10 (1), 103, 2019 | 257 | 2019 |
Synthetic ecology of microbes: mathematical models and applications AR Zomorrodi, D Segrè Journal of molecular biology 428 (5), 837-861, 2016 | 219 | 2016 |
Remnants of an ancient metabolism without phosphate JE Goldford, H Hartman, TF Smith, D Segrè Cell 168 (6), 1126-1134. e9, 2017 | 211 | 2017 |
Composing life D Segré, D Lancet EMBO reports, 2000 | 168 | 2000 |
Graded autocatalysis replication domain (GARD): kinetic analysis of self-replication in mutually catalytic sets D Segré, D Lancet*, O Kedem, Y Pilpel Origins of Life and Evolution of the Biosphere 28, 501-514, 1998 | 153 | 1998 |
Ecosystems biology of microbial metabolism N Klitgord, D Segrè Current opinion in biotechnology 22 (4), 541-546, 2011 | 135 | 2011 |
Genome-driven evolutionary game theory helps understand the rise of metabolic interdependencies in microbial communities AR Zomorrodi, D Segrè Nature communications 8 (1), 1563, 2017 | 130 | 2017 |
Microbial carbon use efficiency predicted from genome-scale metabolic models M Saifuddin, JM Bhatnagar, D Segrè, AC Finzi Nature communications 10 (1), 3568, 2019 | 122 | 2019 |
Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY SR Brinsmade, EL Alexander, J Livny, AI Stettner, D Segrè, KY Rhee, ... Proceedings of the National Academy of Sciences 111 (22), 8227-8232, 2014 | 114 | 2014 |