Recurrent gain-of-function USP8 mutations in Cushing's disease ZY Ma, ZJ Song, JH Chen, YF Wang, SQ Li, LF Zhou, Y Mao, YM Li, ... Cell research 25 (3), 306-317, 2015 | 343 | 2015 |
Anti-tumor effect of β-elemene in glioblastoma cells depends on p38 MAPK activation YQ Yao, X Ding, YC Jia, CX Huang, YZ Wang, YH Xu Cancer letters 264 (1), 127-134, 2008 | 237 | 2008 |
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ... Cell reports 4 (3), 578-588, 2013 | 193 | 2013 |
The genome-wide mutational landscape of pituitary adenomas ZJ Song, ZJ Reitman, ZY Ma, JH Chen, QL Zhang, XF Shou, CX Huang, ... Cell research 26 (11), 1255-1259, 2016 | 142 | 2016 |
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms C Huang, K Hatzi, A Melnick Nature immunology 14 (4), 380-388, 2013 | 136 | 2013 |
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia H Geng, C Hurtz, KB Lenz, Z Chen, D Baumjohann, S Thompson, ... Cancer cell 27 (3), 409-425, 2015 | 131 | 2015 |
Identification of recurrent USP48 and BRAF mutations in Cushing’s disease J Chen, X Jian, S Deng, Z Ma, X Shou, Y Shen, Q Zhang, Z Song, Z Li, ... Nature communications 9 (1), 3171, 2018 | 129 | 2018 |
Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation C Huang, H Geng, I Boss, L Wang, A Melnick Blood, The Journal of the American Society of Hematology 123 (7), 1012-1020, 2014 | 122 | 2014 |
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint S Swaminathan, C Huang, H Geng, Z Chen, R Harvey, H Kang, C Ng, ... Nature medicine 19 (8), 1014-1022, 2013 | 120 | 2013 |
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia B Kharabi Masouleh, H Geng, C Hurtz, LN Chan, AC Logan, MS Chang, ... Proceedings of the National Academy of Sciences 111 (21), E2219-E2228, 2014 | 103 | 2014 |
SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation X Yu, Y Lao, XL Teng, S Li, Y Zhou, F Wang, X Guo, S Deng, Y Chang, ... Nature communications 9 (1), 3157, 2018 | 102 | 2018 |
HDAC3 inhibition upregulates PD-L1 expression in B-cell lymphomas and augments the efficacy of anti–PD-L1 therapy S Deng, Q Hu, H Zhang, F Yang, C Peng, C Huang Molecular cancer therapeutics 18 (5), 900-908, 2019 | 93 | 2019 |
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers C Huang, DG Gonzalez, CM Cote, Y Jiang, K Hatzi, M Teater, K Dai, T Hla, ... Cell reports 8 (5), 1497-1508, 2014 | 91 | 2014 |
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia H Geng, S Brennan, TA Milne, WY Chen, Y Li, C Hurtz, SM Kweon, L Zickl, ... Cancer discovery 2 (11), 1004-1023, 2012 | 89 | 2012 |
PTEN C-terminal deletion causes genomic instability and tumor development Z Sun, C Huang, J He, KL Lamb, X Kang, T Gu, WH Shen, Y Yin Cell reports 6 (5), 844-854, 2014 | 86 | 2014 |
Excessive CD11c+ Tbet+ B cells promote aberrant TFH differentiation and affinity-based germinal center selection in lupus W Zhang, H Zhang, S Liu, F Xia, Z Kang, Y Zhang, Y Liu, H Xiao, L Chen, ... Proceedings of the National Academy of Sciences 116 (37), 18550-18560, 2019 | 82 | 2019 |
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity H Peng, F Yang, Q Hu, J Sun, C Peng, Y Zhao, C Huang Autophagy 16 (4), 698-708, 2020 | 70 | 2020 |
Germline mutations in CDH23, encoding cadherin-related 23, are associated with both familial and sporadic pituitary adenomas Q Zhang, C Peng, J Song, Y Zhang, J Chen, Z Song, X Shou, Z Ma, ... The American Journal of Human Genetics 100 (5), 817-823, 2017 | 70 | 2017 |
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin‐B‐cell lymphoma 6 signaling KH Park‐Min, EY Lee, NK Moskowitz, E Lim, SK Lee, JA Lorenzo, ... Journal of Bone and Mineral Research 28 (1), 135-149, 2013 | 63 | 2013 |
Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression C Huang, Y Jia, S Yang, B Chen, H Sun, F Shen, Y Wang Experimental cell research 313 (2), 254-263, 2007 | 54 | 2007 |