The Chlamydial Plasmid-Encoded Protein pgp3 Is Secreted into the Cytosol of Chlamydia-Infected Cells Z Li, D Chen, Y Zhong, S Wang, G Zhong Infection and immunity 76 (8), 3415-3428, 2008 | 208 | 2008 |
Characterization of Fifty Putative Inclusion Membrane Proteins Encoded in the Chlamydia trachomatis Genome Z Li, C Chen, D Chen, Y Wu, Y Zhong, G Zhong Infection and immunity 76 (6), 2746-2757, 2008 | 170 | 2008 |
Intracellular Interleukin-1α Mediates Interleukin-8 Production Induced by Chlamydia trachomatis Infection via a Mechanism Independent of Type I Interleukin-1 … W Cheng, P Shivshankar, Y Zhong, D Chen, Z Li, G Zhong Infection and immunity 76 (3), 942-951, 2008 | 112 | 2008 |
Structural basis for activation and inhibition of the secreted chlamydia protease CPAF Z Huang, Y Feng, D Chen, X Wu, S Huang, X Wang, X Xiao, W Li, ... Cell host & microbe 4 (6), 529-542, 2008 | 102 | 2008 |
Characterization of Pgp3, a Chlamydia trachomatis Plasmid-Encoded Immunodominant Antigen D Chen, L Lei, C Lu, A Galaleldeen, PJ Hart, G Zhong Journal of bacteriology 192 (22), 6017-6024, 2010 | 100 | 2010 |
Elevated CNS inflammation in patients with preclinical Alzheimer's disease NL Monson, SJ Ireland, AJ Ligocki, D Chen, WH Rounds, M Li, ... Journal of Cerebral Blood Flow & Metabolism 34 (1), 30-33, 2014 | 98 | 2014 |
Inebilizumab, a B cell-depleting anti-CD19 antibody for the treatment of autoimmune neurological diseases: insights from preclinical studies D Chen, S Gallagher, NL Monson, R Herbst, Y Wang Journal of clinical medicine 5 (12), 107, 2016 | 86 | 2016 |
The hypothetical protein CT813 is localized in the Chlamydia trachomatis inclusion membrane and is immunogenic in women urogenitally infected with C. trachomatis C Chen, D Chen, J Sharma, W Cheng, Y Zhong, K Liu, J Jensen, R Shain, ... Infection and immunity 74 (8), 4826-4840, 2006 | 80 | 2006 |
Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway D Chen, L Lei, C Lu, R Flores, MP DeLisa, TC Roberts, FE Romesberg, ... Microbiology 156 (10), 3031-3040, 2010 | 72 | 2010 |
Repetitive hypoxic preconditioning induces an immunosuppressed B cell phenotype during endogenous protection from stroke NL Monson, SB Ortega, SJ Ireland, AJM Meeuwissen, D Chen, EJ Plautz, ... Journal of neuroinflammation 11, 1-18, 2014 | 62 | 2014 |
The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol X Wu, L Lei, S Gong, D Chen, R Flores, G Zhong BMC microbiology 11, 1-16, 2011 | 62 | 2011 |
Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium A Balakrishnan, B Patel, SA Sieber, D Chen, N Pachikara, G Zhong, ... Journal of Biological Chemistry 281 (24), 16691-16699, 2006 | 62 | 2006 |
CD40-mediated NF-κB activation in B cells is increased in multiple sclerosis and modulated by therapeutics D Chen, SJ Ireland, G Remington, E Alvarez, MK Racke, B Greenberg, ... The Journal of Immunology 197 (11), 4257-4265, 2016 | 53 | 2016 |
Structure of the Chlamydia trachomatis immunodominant antigen Pgp3 A Galaleldeen, AB Taylor, D Chen, JP Schuermann, SP Holloway, S Hou, ... Journal of Biological Chemistry 288 (30), 22068-22079, 2013 | 51 | 2013 |
Immunization with chlamydial plasmid protein pORF5 DNA vaccine induces protective immunity against genital chlamydial infection in mice ZY Li, SP Wang, YM Wu, GM Zhong, D Chen Science in China Series C: Life Sciences 51 (11), 973-980, 2008 | 51 | 2008 |
Autoreactive CD19+ CD20− plasma cells contribute to disease severity of experimental autoimmune encephalomyelitis D Chen, SJ Ireland, LS Davis, X Kong, AM Stowe, Y Wang, WI White, ... The Journal of Immunology 196 (4), 1541-1549, 2016 | 47 | 2016 |
Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients JR Rivas, SJ Ireland, R Chkheidze, WH Rounds, J Lim, J Johnson, ... Acta neuropathologica 133, 43-60, 2017 | 44 | 2017 |
Single dose of glycoengineered anti-CD19 antibody (MEDI551) disrupts experimental autoimmune encephalomyelitis by inhibiting pathogenic adaptive immune responses in the bone … D Chen, M Blazek, S Ireland, S Ortega, X Kong, A Meeuwissen, A Stowe, ... The Journal of Immunology 193 (10), 4823-4832, 2014 | 37 | 2014 |
Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells D Chen, L Lei, R Flores, Z Huang, Z Wu, J Chai, G Zhong Microbial pathogenesis 49 (4), 164-173, 2010 | 34 | 2010 |
Identifying catalytic residues in CPAF, a Chlamydia-secreted protease D Chen, J Chai, PJ Hart, G Zhong Archives of biochemistry and biophysics 485 (1), 16-23, 2009 | 34 | 2009 |