The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double … RA Pugh, M Honda, H Leesley, A Thomas, Y Lin, MJ Nilges, IKO Cann, ... Journal of Biological Chemistry 283 (3), 1732-1743, 2008 | 121 | 2008 |
Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase M Honda, J Park, RA Pugh, T Ha, M Spies Molecular cell 35 (5), 694-703, 2009 | 95 | 2009 |
Sequence-dependent base pair stepping dynamics in XPD helicase unwinding YRC Zhi Qi, Robert A. Pugh, Maria Spies eLife 2, e00334, 2013 | 91 | 2013 |
Regulation of translocation polarity by helicase domain 1 in SF2B helicases RA Pugh, CG Wu, M Spies The EMBO Journal, 2011 | 75 | 2011 |
Ferroplasma acidarmanus RPA2 facilitates efficient unwinding of forked DNA substrates by monomers of FacXPD helicase RA Pugh, Y Lin, C Eller, H Leesley, IKO Cann, M Spies Journal of molecular biology 383 (5), 982-998, 2008 | 44 | 2008 |
Ensemble and single-molecule fluorescence-based assays to monitor DNA binding, translocation, and unwinding by iron–sulfur cluster containing helicases RA Pugh, M Honda, M Spies Methods 51 (3), 313-321, 2010 | 23 | 2010 |
DNA Helicases: Chemistry and Mechanisms RA Pugh, M Spies Wiley Encyclopedia of Chemical Biology, 1-11, 2007 | 1 | 2007 |
Displaced Strand Regulation of Facxpd Helicase Activity Z Qi, RA Pugh, M Spies, YR Chemla Biophysical Journal 100 (3), 73a, 2011 | | 2011 |
XPD helicase: Shifting the inchworm into reverse RA Pugh University of Illinois at Urbana-Champaign, 2009 | | 2009 |
allows us to look at finer details such as DNA slipping and the effect of DNA sequences on unwinding rates. Supported by DFG, SFB 863, Freidrich Baur-Stiftung and EMBO. 387-Pos … Z Qi, RA Pugh, M Spies, YR Chemla | | |