Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings CM Chu, VCC Cheng, IFN Hung, MML Wong, KH Chan, KS Chan, ... Thorax 59 (3), 252-256, 2004 | 2089 | 2004 |
In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds F Chen, KH Chan, Y Jiang, RYT Kao, HT Lu, KW Fan, VCC Cheng, ... Journal of clinical virology 31 (1), 69-75, 2004 | 700 | 2004 |
Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus JFW Chan, KH Chan, RYT Kao, KKW To, BJ Zheng, CPY Li, PTW Li, J Dai, ... Journal of Infection 67 (6), 606-616, 2013 | 488 | 2013 |
Identification of influenza A nucleoprotein as an antiviral target RY Kao, D Yang, LS Lau, WHW Tsui, L Hu, J Dai, MP Chan, CM Chan, ... Nature biotechnology 28 (6), 600-605, 2010 | 286 | 2010 |
Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan, H Shuai, Y Wang, ... Viruses 11 (1), 73, 2019 | 265 | 2019 |
Fluorescent probe HKSOX-1 for imaging and detection of endogenous superoxide in live cells and in vivo JJ Hu, NK Wong, S Ye, X Chen, MY Lu, AQ Zhao, Y Guo, ACH Ma, ... Journal of the American Chemical Society 137 (21), 6837-6843, 2015 | 254 | 2015 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 235 | 2019 |
Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors R Wang, TP Lai, P Gao, H Zhang, PL Ho, PCY Woo, G Ma, RYT Kao, H Li, ... Nature communications 9 (1), 439, 2018 | 223 | 2018 |
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics RY Kao, WHW Tsui, TSW Lee, JA Tanner, RM Watt, JD Huang, L Hu, ... Chemistry & biology 11 (9), 1293-1299, 2004 | 187 | 2004 |
Differential sensitivities of severe acute respiratory syndrome (SARS) coronavirus spike polypeptide enzyme-linked immunosorbent assay (ELISA) and SARS coronavirus nucleocapsid … PCY Woo, SKP Lau, BHL Wong, H Tsoi, AMY Fung, RYT Kao, K Chan, ... Journal of clinical microbiology 43 (7), 3054-3058, 2005 | 162 | 2005 |
Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity L Du, RY Kao, Y Zhou, Y He, G Zhao, C Wong, S Jiang, KY Yuen, DY Jin, ... Biochemical and biophysical research communications 359 (1), 174-179, 2007 | 154 | 2007 |
HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay JJ Hu, NK Wong, MY Lu, X Chen, S Ye, AQ Zhao, P Gao, RYT Kao, ... Chemical science 7 (3), 2094-2099, 2016 | 147 | 2016 |
A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity RYT Kao, JL Jenkins, KA Olson, ME Key, JW Fett, R Shapiro Proceedings of the National Academy of Sciences 99 (15), 10066-10071, 2002 | 147 | 2002 |
Antimicrobial activity of Chinese medicine herbs against common bacteria in oral biofilm. A pilot study RWK Wong, U Hägg, L Samaranayake, MKZ Yuen, CJ Seneviratne, ... International journal of oral and maxillofacial surgery 39 (6), 599-605, 2010 | 146 | 2010 |
Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor JFW Chan, KKH Chik, S Yuan, CCY Yip, Z Zhu, KM Tee, JOL Tsang, ... Antiviral research 141, 29-37, 2017 | 133 | 2017 |
Virtual screening to enrich hit lists from high‐throughput screening: A case study on small‐molecule inhibitors of angiogenin JL Jenkins, RYT Kao, R Shapiro Proteins: Structure, Function, and Bioinformatics 50 (1), 81-93, 2003 | 129 | 2003 |
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance H Wang, M Wang, X Xu, P Gao, Z Xu, Q Zhang, H Li, A Yan, RYT Kao, ... Nature communications 12 (1), 3331, 2021 | 122 | 2021 |
Vancomycin MIC creep in MRSA isolates from 1997 to 2008 in a healthcare region in Hong Kong PL Ho, PY Lo, KH Chow, EHY Lau, EL Lai, VCC Cheng, RY Kao Journal of Infection 60 (2), 140-145, 2010 | 112 | 2010 |
In vitro and in vivo activity of a novel antifungal small molecule against Candida infections SSW Wong, RYT Kao, KY Yuen, Y Wang, D Yang, LP Samaranayake, ... PLoS one 9 (1), e85836, 2014 | 107 | 2014 |
Resensitizing carbapenem-and colistin-resistant bacteria to antibiotics using auranofin H Sun, Q Zhang, R Wang, H Wang, YT Wong, M Wang, Q Hao, A Yan, ... Nature communications 11 (1), 5263, 2020 | 94 | 2020 |