| A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 1757 | 2016 |
| Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ... Nature 568 (7753), 511-516, 2019 | 1034 | 2019 |
| Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ... Nature 537 (7621), 544-547, 2016 | 528 | 2016 |
| CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms CDA Terfve, T Cokelaer, D Henriques, A MacNamara, E Gonçalves, ... BMC Systems Biology 6 (1), 133, 2012 | 241 | 2012 |
| SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 211 | 2020 |
| Integrated cross-study datasets of genetic dependencies in cancer C Pacini, JM Dempster, I Boyle, E Gonçalves, H Najgebauer, E Karakoc, ... Nature communications 12 (1), 1661, 2021 | 199 | 2021 |
| SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools C Chaouiya, D Bérenguier, SM Keating, A Naldi, MP Van Iersel, ... BMC systems biology 7, 1-15, 2013 | 189 | 2013 |
| Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ... Nature communications 10 (1), 5817, 2019 | 183 | 2019 |
| Genomic determinants of protein abundance variation in colorectal cancer cells TI Roumeliotis, SP Williams, E Goncalves, FZ Ghavidel, N Aben, ... Cell Reports 20 (9), 2201–2214, 2017 | 115 | 2017 |
| Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models E Gonçalves, J Bucher, A Ryll, J Niklas, K Mauch, S Klamt, M Rocha, ... Molecular BioSystems 9 (7), 1576-1583, 2013 | 113 | 2013 |
| Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening G Picco, ED Chen, LG Alonso, FM Behan, E Gonçalves, G Bignell, ... Nature communications 10 (1), 2198, 2019 | 108 | 2019 |
| Widespread post-transcriptional attenuation of genomic copy-number variation in cancer E Gonçalves, A Fragoulis, L Garcia-Alonso, T Cramer, J Saez-Rodriguez, ... Cell systems 5 (4), 386-398. e4, 2017 | 107 | 2017 |
| Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting F Iorio, FM Behan, E Gonçalves, SG Bhosle, E Chen, R Shepherd, ... BMC genomics 19, 1-16, 2018 | 89 | 2018 |
| DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data C Pacini, F Iorio, E Gonçalves, M Iskar, T Klabunde, P Bork, ... Bioinformatics 29 (1), 132-134, 2013 | 82 | 2013 |
| Pan-cancer proteomic map of 949 human cell lines E Gonçalves, RC Poulos, Z Cai, S Barthorpe, SS Manda, N Lucas, A Beck, ... Cancer Cell 40 (8), 835-849. e8, 2022 | 76 | 2022 |
| Combinatorial CRISPR screen identifies fitness effects of gene paralogues NA Thompson, M Ranzani, L van der Weyden, V Iyer, V Offord, A Droop, ... Nature communications 12 (1), 1302, 2021 | 75 | 2021 |
| Benchmarking substrate-based kinase activity inference using phosphoproteomic data C Hernandez-Armenta, D Ochoa, E Gonçalves, J Saez-Rodriguez, ... Bioinformatics 33 (12), 1845-1851, 2017 | 75 | 2017 |
| Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens E Goncalves, A Segura-Cabrera, C Pacini, G Picco, F Behan, P Jaaks, ... Molecular Systems Biology, 2020 | 73 | 2020 |
| Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets L Dwane, FM Behan, E Gonçalves, H Lightfoot, W Yang, D van der Meer, ... Nucleic Acids Research 49 (D1), D1365-D1372, 2021 | 63 | 2021 |
| Minimal genome-wide human CRISPR-Cas9 library E Gonçalves, M Thomas, FM Behan, G Picco, C Pacini, F Allen, A Vinceti, ... Genome biology 22, 1-14, 2021 | 53 | 2021 |
Julio Saez RodriguezHeidelberg University在 uni-heidelberg.de 的电子邮件经过验证
