Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling HG Pálmer, JM González-Sancho, J Espada, MT Berciano, I Puig, ... The Journal of cell biology 154 (2), 369-388, 2001 | 1008 | 2001 |
Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 680 | 2017 |
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate β-catenin Tyr-142 phosphorylation and β-catenin-α-catenin Interaction J Piedra, S Miravet, J Castaño, HG Pálmer, N Heisterkamp, ... Molecular and cellular biology, 2003 | 459 | 2003 |
β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer SP Tenbaum, P Ordóñez-Morán, I Puig, I Chicote, O Arqués, S Landolfi, ... Nature medicine 18 (6), 892-901, 2012 | 433 | 2012 |
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer HG Pálmer, MJ Larriba, JM García, P Ordóñez-Morán, C Peña, S Peiró, ... Nature medicine 10 (9), 917-919, 2004 | 358 | 2004 |
Genetic Signatures of Differentiation Induced by 1α,25-Dihydroxyvitamin D3 in Human Colon Cancer Cells HG Pálmer, M Sánchez-Carbayo, P Ordóñez-Morán, MJ Larriba, ... Cancer research 63 (22), 7799-7806, 2003 | 266 | 2003 |
Colorectal cancer consensus molecular subtypes translated to preclinical models uncover potentially targetable cancer cell dependencies A Sveen, J Bruun, PW Eide, IA Eilertsen, L Ramirez, A Murumägi, ... Clinical Cancer Research 24 (4), 794-806, 2018 | 236 | 2018 |
DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α, 25-dihydroxyvitamin D3 N Pendás-Franco, JM García, C Peña, N Valle, HG Pálmer, M Heinäniemi, ... Oncogene 27 (32), 4467-4477, 2008 | 203 | 2008 |
Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer MJ Larriba, P Ordonez-Moran, I Chicote, G Martin-Fernandez, I Puig, ... PloS one 6 (8), e23524, 2011 | 184 | 2011 |
The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis HG Pálmer, F Anjos-Afonso, G Carmeliet, H Takeda, FM Watt PloS one 3 (1), e1483, 2008 | 181 | 2008 |
Tankyrase inhibition blocks Wnt/β-catenin pathway and reverts resistance to PI3K and AKT inhibitors in the treatment of colorectal cancer O Arqués, I Chicote, I Puig, SP Tenbaum, G Argilés, R Dienstmann, ... Clinical cancer research 22 (3), 644-656, 2016 | 172 | 2016 |
Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes A Herrero, A Pinto, P Colón-Bolea, B Casar, M Jones, L Agudo-Ibáñez, ... Cancer cell 28 (2), 170-182, 2015 | 153 | 2015 |
RhoA–ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells P Ordóñez-Morán, MJ Larriba, HG Pálmer, RA Valero, A Barbáchano, ... The Journal of cell biology 183 (4), 697-710, 2008 | 149 | 2008 |
1α, 25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells NI Fernandez-Garcia, HG Palmer, M Garcia, A Gonzalez-Martin, ... Oncogene 24 (43), 6533-6544, 2005 | 135 | 2005 |
CD34− cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures F Anjos-Afonso, E Currie, HG Palmer, KE Foster, DC Taussig, D Bonnet Cell stem cell 13 (2), 161-174, 2013 | 131 | 2013 |
The inhibition of Wnt/β-catenin signalling by 1α, 25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells MJ Larriba, N Valle, HG Palmer, P Ordonez-Moran, S Álvarez-Díaz, ... Endocrine-related cancer 14 (1), 141-151, 2007 | 122 | 2007 |
TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence I Puig, SP Tenbaum, I Chicote, O Arques, J Martinez-Quintanilla, ... The Journal of clinical investigation 128 (9), 3887-3905, 2018 | 103 | 2018 |
A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells I Puig, I Chicote, SP Tenbaum, O Arqués, JR Herance, JD Gispert, ... Clinical Cancer Research 19 (24), 6787-6801, 2013 | 98 | 2013 |
BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways L Jubierre, A Soriano, L Planells-Ferrer, L París-Coderch, SP Tenbaum, ... Oncogene 35 (39), 5179-5190, 2016 | 88 | 2016 |
Effects of 1α, 25-dihydroxyvitamin D3 in human colon cancer cells JM Gonzalez-Sancho, MJ Larriba, P Ordonez-Moran, HG Palmer, ... Anticancer research 26 (4A), 2669-2681, 2006 | 87 | 2006 |