Direct inhibition of GSK3β by the phosphorylated cytoplasmic domain of LRP6 in Wnt/β-catenin signaling S Piao, SH Lee, H Kim, S Yum, JL Stamos, Y Xu, SJ Lee, J Lee, S Oh, ... PloS one 3 (12), e4046, 2008 | 260 | 2008 |
Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function SH Lee, SJ Lee, YS Jung, Y Xu, HS Kang, NC Ha, BJ Park Neoplasia 11 (1), 22-IN6, 2009 | 120 | 2009 |
Redox‐switch modulation of human SSADH by dynamic catalytic loop YG Kim, S Lee, OS Kwon, SY Park, SJ Lee, BJ Park, KJ Kim The EMBO journal 28 (7), 959-968, 2009 | 99 | 2009 |
PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness X Wang, YS Jung, S Jun, S Lee, W Wang, A Schneider, Y Sun Oh, SH Lin, ... Nature communications 7 (1), 10633, 2016 | 87 | 2016 |
Wnt2 complements Wnt/β-catenin signaling in colorectal cancer YS Jung, S Jun, SH Lee, A Sharma, JI Park Oncotarget 6 (35), 37257, 2015 | 74 | 2015 |
Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease JY Chung, SJ Lee, SH Lee, YS Jung, NC Ha, W Seol, BJ Park Neurosignals 19 (2), 86-96, 2011 | 49 | 2011 |
Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells SH Lee, GN Shen, YS Jung, SJ Lee, JY Chung, HS Kim, Y Xu, Y Choi, ... Oncogene 29 (32), 4576-4587, 2010 | 48 | 2010 |
PAF-mediated MAPK signaling hyperactivation via LAMTOR3 induces pancreatic tumorigenesis S Jun, S Lee, HC Kim, C Ng, AM Schneider, H Ji, H Ying, H Wang, ... Cell reports 5 (2), 314-322, 2013 | 46 | 2013 |
Elevated TRAF2/6 expression in Parkinson’s disease is caused by the loss of Parkin E3 ligase activity JY Chung, HR Park, SJ Lee, SH Lee, JS Kim, YS Jung, SH Hwang, ... Laboratory investigation 93 (6), 663-676, 2013 | 46 | 2013 |
A new p53 target gene, RKIP, is essential for DNA damage-induced cellular senescence and suppression of ERK activation SJ Lee, SH Lee, MH Yoon, BJ Park Neoplasia 15 (7), 727-IN11, 2013 | 42 | 2013 |
p53, secreted by K-Ras–Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker SH Lee, SJ Lee, JY Chung, YS Jung, SY Choi, SH Hwang, D Choi, NC Ha, ... Oncogene 28 (19), 2005-2014, 2009 | 41 | 2009 |
Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions YS Jung, SJ Lee, MH Yoon, NC Ha, BJ Park Cell cycle 11 (23), 4462-4473, 2012 | 40 | 2012 |
Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1–PUMA pathway SH Lee, YS Jung, JY Chung, AY Oh, SJ Lee, DH Choi, SM Jang, KS Jang, ... Cell death & disease 2 (12), e235-e235, 2011 | 40 | 2011 |
The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors S Yum, SJ Lee, S Piao, Y Xu, J Jung, Y Jung, S Oh, J Lee, BJ Park, NC Ha Biochemical and biophysical research communications 381 (3), 345-349, 2009 | 28 | 2009 |
Identification of KIAA1199 as a biomarker for pancreatic intraepithelial neoplasia HN Suh, S Jun, AY Oh, M Srivastava, S Lee, CM Taniguchi, S Zhang, ... Scientific reports 6 (1), 38273, 2016 | 26 | 2016 |
Systems analysis reveals a transcriptional reversal of the mesenchymal phenotype induced by SNAIL-inhibitor GN-25 AS Azmi, A Bollig-Fischer, B Bao, BJ Park, SH Lee, G Yong-Song, ... BMC systems biology 7, 1-12, 2013 | 25 | 2013 |
CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation S Piao, SJ Lee, Y Xu, J Gwak, S Oh, BJ Park, NC Ha Cell Cycle 10 (3), 531-537, 2011 | 24 | 2011 |
Loss of VHL promotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity YS Jung, SJ Lee, SH Lee, JY Chung, YJ Jung, SH Hwang, NC Ha, ... Cell cycle 12 (14), 2277-2290, 2013 | 23 | 2013 |
Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening SJ Lee, YS Jung, SH Lee, HY Chung, BJ Park International journal of oncology 34 (6), 1637-1643, 2009 | 23 | 2009 |
Chemical Carcinogen, N-methyl-N’-nitro-N-nitrosoguanidine, is Specific Activator of Oncogenic Ras SH Lee, SJ Lee, JH Kim, BJ Park Cell Cycle 6 (10), 1257-1264, 2007 | 16 | 2007 |