| Development and characterization of a preclinical model of breast cancer lung micrometastatic to macrometastatic progression LC Bailey-Downs, JE Thorpe, BC Disch, A Bastian, PJ Hauser, T Farasyn, ... PloS one 9 (5), e98624, 2014 | 94 | 2014 |
| The design and discovery of water soluble 4-substituted-2, 6-dimethylfuro [2, 3-d] pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting … X Zhang, S Raghavan, M Ihnat, JE Thorpe, BC Disch, A Bastian, ... Bioorganic & medicinal chemistry 22 (14), 3753-3772, 2014 | 57 | 2014 |
| AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization A Bastian, S Matsuzaki, KM Humphries, GA Pharaoh, A Doshi, N Zaware, ... Cancer letters 388, 149-157, 2017 | 45 | 2017 |
| Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potential A Gangjee, RK Pavana, MA Ihnat, JE Thorpe, BC Disch, A Bastian, ... ACS medicinal chemistry letters 5 (5), 480-484, 2014 | 43 | 2014 |
| The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2, 6-dimethylfuro [2, 3-d] pyrimidines as multi-targeted receptor tyrosine kinase … X Zhang, S Raghavan, M Ihnat, E Hamel, C Zammiello, A Bastian, ... Bioorganic & medicinal chemistry 23 (10), 2408-2423, 2015 | 41 | 2015 |
| Interleukin 6 function in the skin and isolated keratinocytes is modulated by hyperglycemia EG Lee, LR Luckett-Chastain, KN Calhoun, B Frempah, A Bastian, ... Journal of immunology research 2019 (1), 5087847, 2019 | 36 | 2019 |
| A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer A Bastian, JE Thorpe, BC Disch, LC Bailey-Downs, A Gangjee, ... Journal of Pharmacology and Experimental Therapeutics 353 (2), 392-404, 2015 | 34 | 2015 |
| Targeting dormant micrometastases: rationale, evidence to date and clinical implications RE Hurst, A Bastian, L Bailey-Downs, MA Ihnat Therapeutic advances in medical oncology 8 (2), 126-137, 2016 | 32 | 2016 |
| Synthesis and biological activity of 5-chloro-N4-substituted phenyl-9H-pyrimido [4, 5-b] indole-2, 4-diamines as vascular endothelial growth factor receptor-2 inhibitors and … A Gangjee, N Zaware, S Raghavan, BC Disch, JE Thorpe, A Bastian, ... Bioorganic & medicinal chemistry 21 (7), 1857-1864, 2013 | 31 | 2013 |
| A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model RA Towner, M Ihnat, D Saunders, A Bastian, N Smith, RK Pavana, ... BMC cancer 15, 1-8, 2015 | 18 | 2015 |
| Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with … RK Pavana, S Choudhary, A Bastian, MA Ihnat, R Bai, E Hamel, ... Bioorganic & medicinal chemistry 25 (2), 545-556, 2017 | 17 | 2017 |
| Synthesis and evaluation of 5-(arylthio)-9H-pyrimido [4, 5-b] indole-2, 4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents N Zaware, R Kisliuk, A Bastian, MA Ihnat, A Gangjee Bioorganic & medicinal chemistry letters 27 (7), 1602-1607, 2017 | 16 | 2017 |
| Identification of novel drugs to target dormant micrometastases RE Hurst, PJ Hauser, Y You, LC Bailey-Downs, A Bastian, SM Matthews, ... BMC cancer 15, 1-12, 2015 | 16 | 2015 |
| AG488 as a therapy against gliomas J Ziegler, A Bastian, M Lerner, L Bailey-Downs, D Saunders, N Smith, ... Oncotarget 8 (42), 71833, 2017 | 4 | 2017 |
| Design and biological evaluation of substituted pyrrolo [3, 2-d] pyrimidines as dual acting RTK and microtubule targeting agents A Gangjee, K Shah, N Dybdal-Hargreaves, S Mooberry, A Bastian, ... Cancer Research 76 (14_Supplement), 4857-4857, 2016 | 3 | 2016 |
| Cell non-autonomous interactions during non-immune stromal progression in the breast tumor microenvironment R Utama, A Bastian, N Sadagopan, Y Jin, E Antoniou, Q Gao, YJ Huang, ... BioRxiv, 540112, 2019 | 1 | 2019 |
| Design, synthesis, and biological evaluation of thieno [2, 3-d] and thieno [3, 2-d] pyrimidines as dual acting RTK inhibitors and microtubule targeting antitumor agents A Gangjee, F Islam, TM Quadery, SL Mooberry, A Bastian, MA Ihnat Cancer Research 76 (14_Supplement), 4837-4837, 2016 | 1 | 2016 |
| Abstract LB-357: Transcriptional landscape of stroma progression in the breast tumor microenvironment R Utama, A Bastian, N Sadagopan, Y Jin, E Antoniou, Y Huang, P Lee, ... Cancer Research 78 (13_Supplement), LB-357-LB-357, 2018 | | 2018 |
| A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer (vol 353, pg 392, 2015) A Bastian, JE Thorpe, BC Disch, LC Bailey-Downs, A Gangjee, D Rkv, ... JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 360 (1), 225-225, 2017 | | 2017 |
| Mechanistic evaluation of AG311-an OXPHOS inhibitor-as a potential treatment for breast cancer A Bastian, S Matsuzaki, KM Humphries, LC Bailey-Downs, A Gangjee, ... Cancer Research 76 (14_Supplement), 3776-3776, 2016 | | 2016 |
