An atlas of β-glucuronidases in the human intestinal microbiome RM Pollet, EH D'Agostino, WG Walton, Y Xu, MS Little, KA Biernat, ... Structure 25 (7), 967-977. e5, 2017 | 249 | 2017 |
Risk factors for gaps in care during transfer from pediatric to adult cystic fibrosis programs in the United States GS Sawicki, J Ostrenga, K Petren, AK Fink, E D’Agostino, C Strassle, ... Annals of the American Thoracic Society 15 (2), 234-240, 2018 | 51 | 2018 |
Structural analysis of the glucocorticoid receptor ligand-binding domain in complex with triamcinolone acetonide and a fragment of the atypical coregulator, small heterodimer … ER Weikum, CD Okafor, EH D’Agostino, JK Colucci, EA Ortlund Molecular pharmacology 92 (1), 12-21, 2017 | 22 | 2017 |
Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition JL Cornelison, ML Cato, AM Johnson, EH D'Agostino, D Melchers, ... Bioorganic & medicinal chemistry letters 30 (16), 127293, 2020 | 20 | 2020 |
Development of a versatile and sensitive direct ligand binding assay for human NR5A nuclear receptors EH D’Agostino, AR Flynn, JL Cornelison, SG Mays, A Patel, NT Jui, ... ACS Medicinal Chemistry Letters 11 (3), 365-370, 2019 | 12 | 2019 |
A phospholipid mimetic targeting LRH-1 ameliorates colitis SG Mays, EH D’Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ... Cell Chemical Biology 29 (7), 1174-1186. e7, 2022 | 9 | 2022 |
Differential modulation of nuclear receptor LRH-1 through targeting buried and surface regions of the binding pocket ML Cato, JL Cornelison, RM Spurlin, VV Courouble, AB Patel, AR Flynn, ... Journal of medicinal chemistry 65 (9), 6888-6902, 2022 | 8 | 2022 |
Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators ML Cato, EH D’Agostino, RM Spurlin, AR Flynn, JL Cornelison, ... Journal of Biological Chemistry 299 (8), 2023 | 5 | 2023 |
Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist SG Mays, J Stec, X Liu, EH D’Agostino, RJ Whitby, EA Ortlund Scientific Reports 10 (1), 22279, 2020 | 5 | 2020 |
A novel phospholipid mimetic targeting LRH-1 ameliorates colitis SG Mays, EH D’Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ... | 2* | 2020 |
Uniting features from strongly activating small molecules to develop chimeric LRH‐1 agonist M Cato, J Cornelison, A Flynn, A Johnson, C Okafor, N Jui, A Patel, ... The FASEB Journal 35, 2021 | | 2021 |
Development of picomolar liver receptor homolog‐1 agonist ML Cato, J Cornelison, A Flynn, E D’Agostino, N Jui, E Ortlund The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Structure-Function Studies of the NR5A Nuclear Receptors EH D'Agostino Emory University, 2020 | | 2020 |
Development of a Robust Direct Binding Assay for Phospholipid‐Sensing NR5A Nuclear Receptors EH D'Agostino, J Cornelison, S Mays, A Flynn, N Jui, E Ortlund The FASEB Journal 33 (S1), 634.3-634.3, 2019 | | 2019 |
ADVANCING RESEARCH THAT MATTERS MOST TO PATIENTS AND FAMILIES: PRELIMINARY FINDINGS FROM THE INSIGHT CF REGISTRY RESEARCH PROJECT C Strassle, B Gamel, D Hansen, M Barloewen, M Bellefeuille, A Campbell, ... PEDIATRIC PULMONOLOGY 52, S424-S424, 2017 | | 2017 |
The Human GI Microbial GUSome, a Constellation of Drug Targets in the Microbiome E D'Agostino | | 2016 |