Malignant astrocytic glioma: genetics, biology, and paths to treatment FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ... Genes & development 21 (21), 2683-2710, 2007 | 2891 | 2007 |
Pancreatic cancers require autophagy for tumor growth S Yang, X Wang, G Contino, M Liesa, E Sahin, H Ying, A Bause, Y Li, ... Genes & development 25 (7), 717-729, 2011 | 1597 | 2011 |
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ... Science 318 (5848), 287-290, 2007 | 1118 | 2007 |
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking JM Stommel, ND Marchenko, GS Jimenez, UM Moll, TJ Hope, GM Wahl The EMBO journal 18 (6), 1660-1672, 1999 | 989 | 1999 |
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ... Nature 455 (7216), 1129-1133, 2008 | 860 | 2008 |
Accelerated MDM2 auto‐degradation induced by DNA‐damage kinases is required for p53 activation JM Stommel, GM Wahl The EMBO journal 23 (7), 1547-1556, 2004 | 470 | 2004 |
A transactivation-deficient mouse model provides insights into Trp53 regulation and function GS Jimenez, M Nister, JM Stommel, M Beeche, EA Barcarse, XQ Zhang, ... Nature genetics 26 (1), 37-43, 2000 | 271 | 2000 |
p53 regulation by post-translational modification and nuclear retention in response to diverse stresses GS Jimenez, SH Khan, JM Stommel, GM Wahl Oncogene 18 (53), 7656-7665, 1999 | 259 | 1999 |
Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCFβ-TRCP ubiquitin ligase H Inuzuka, A Tseng, D Gao, B Zhai, Q Zhang, S Shaik, L Wan, XL Ang, ... Cancer cell 18 (2), 147-159, 2010 | 230 | 2010 |
Hdmx modulates the outcome of p53 activation in human tumor cells M Wade, ET Wong, M Tang, JM Stommel, GM Wahl Journal of Biological Chemistry 281 (44), 33036-33044, 2006 | 213 | 2006 |
Mig-6 controls EGFR trafficking and suppresses gliomagenesis H Ying, H Zheng, K Scott, R Wiedemeyer, H Yan, C Lim, J Huang, ... Proceedings of the National Academy of Sciences 107 (15), 6912-6917, 2010 | 146 | 2010 |
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ... Cold Spring Harbor symposia on quantitative biology 73, 427-437, 2008 | 145 | 2008 |
A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation JM Stommel, GM Wahl Cell cycle 4 (3), 411-417, 2005 | 136 | 2005 |
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy M Nitta, D Kozono, R Kennedy, J Stommel, K Ng, PO Zinn, D Kushwaha, ... PloS one 5 (5), e10767, 2010 | 83 | 2010 |
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level G Yuen, FJ Khan, S Gao, JM Stommel, E Batchelor, X Wu, J Luo Nucleic acids research 45 (20), 12039-12053, 2017 | 81 | 2017 |
The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans DR Carrasco, T Fenton, K Sukhdeo, M Protopopova, M Enos, MJ You, ... Cancer cell 9 (5), 379-390, 2006 | 81 | 2006 |
Cholesterol metabolism: A potential therapeutic target in glioblastoma F Ahmad, Q Sun, D Patel, JM Stommel Cancers 11 (2), 146, 2019 | 75 | 2019 |
v-Raf activates transcription of growth-responsive promoters via GC-rich sequences that bind the transcription factor Sp1. RJ Miltenberger, PJ Farnham, DE Smith, JM Stommel, MM Cornwell Cell Growth & Differentiation: the Molecular Biology Journal of the American …, 1995 | 66 | 1995 |
Global inhibition with specific activation: how p53 and MYC redistribute the transcriptome in the DNA double-strand break response JR Porter, BE Fisher, L Baranello, JC Liu, DM Kambach, Z Nie, WS Koh, ... Molecular cell 67 (6), 1013-1025. e9, 2017 | 64 | 2017 |
Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma DM Kambach, AS Halim, AG Cauer, Q Sun, CA Tristan, O Celiku, ... Oncotarget 8 (9), 14860, 2017 | 46 | 2017 |