IL-1 family members mediate cell death, inflammation and angiogenesis in retinal degenerative diseases Y Wooff, SM Man, R Aggio-Bruce, R Natoli, N Fernando Frontiers in immunology 10, 462812, 2019 | 182 | 2019 |
Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration R Natoli, N Fernando, M Madigan, JA Chu-Tan, K Valter, J Provis, M Rutar Molecular neurodegeneration 12, 1-11, 2017 | 123 | 2017 |
Retinal macrophages synthesize C3 and activate complement in AMD and in models of focal retinal degeneration R Natoli, N Fernando, H Jiao, T Racic, M Madigan, NL Barnett, ... Investigative ophthalmology & visual science 58 (7), 2977-2990, 2017 | 93 | 2017 |
A model of progressive photo-oxidative degeneration and inflammation in the pigmented C57BL/6J mouse retina R Natoli, H Jiao, NL Barnett, N Fernando, K Valter, JM Provis, M Rutar Experimental eye research 147, 114-127, 2016 | 69 | 2016 |
MicroRNA-124 dysregulation is associated with retinal inflammation and photoreceptor death in the degenerating retina JA Chu-Tan, M Rutar, K Saxena, R Aggio-Bruce, RW Essex, K Valter, ... Investigative ophthalmology & visual science 59 (10), 4094-4105, 2018 | 57 | 2018 |
Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration H Jiao, M Rutar, N Fernando, T Yednock, S Sankaranarayanan, ... Molecular neurodegeneration 13, 1-18, 2018 | 53 | 2018 |
Toll-like receptor 2 facilitates oxidative damage-induced retinal degeneration K Mulfaul, E Ozaki, N Fernando, K Brennan, KR Chirco, E Connolly, ... Cell reports 30 (7), 2209-2224. e5, 2020 | 49 | 2020 |
Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration Y Wooff, N Fernando, JHC Wong, C Dietrich, R Aggio-Bruce, JA Chu-Tan, ... Scientific Reports 10 (1), 2263, 2020 | 33 | 2020 |
The broad-spectrum chemokine inhibitor NR58-3.14. 3 modulates macrophage-mediated inflammation in the diseased retina N Fernando, R Natoli, K Valter, J Provis, M Rutar Journal of neuroinflammation 13, 1-14, 2016 | 32 | 2016 |
Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment R Natoli, N Fernando, T Dahlenburg, H Jiao, R Aggio-Bruce, NL Barnett, ... Molecular vision 24, 201, 2018 | 28 | 2018 |
MicroRNA as therapeutics for age-related macular degeneration R Natoli, N Fernando Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 37-43, 2018 | 27 | 2018 |
Photobiomodulation with 670 nm light ameliorates Müller cell-mediated activation of microglia and macrophages in retinal degeneration YZ Lu, R Natoli, M Madigan, N Fernando, K Saxena, R Aggio-Bruce, ... Experimental eye research 165, 78-89, 2017 | 26 | 2017 |
670nm light treatment following retinal injury modulates Müller cell gliosis: Evidence from in vivo and in vitro stress models YZ Lu, N Fernando, R Natoli, M Madigan, K Valter Experimental eye research 169, 1-12, 2018 | 23 | 2018 |
Interphotoreceptor retinoid-binding protein (IRBP) in retinal health and disease S Zeng, T Zhang, MC Madigan, N Fernando, R Aggio-Bruce, F Zhou, ... Frontiers in Cellular Neuroscience 14, 577935, 2020 | 21 | 2020 |
MicroRNA-223 regulates retinal function and inflammation in the healthy and degenerating retina N Fernando, JHC Wong, S Das, C Dietrich, R Aggio-Bruce, AV Cioanca, ... Frontiers in Cell and Developmental Biology 8, 516, 2020 | 16 | 2020 |
Multi-dimensional gene regulation in innate and adaptive lymphocytes: a view from regulomes N Fernando, G Sciumè, JJ O’Shea, HY Shih Frontiers in immunology 12, 655590, 2021 | 12 | 2021 |
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration S Zeng, T Zhang, Y Chen, J Chu-Tan, K Jin, SR Lee, MX Yam, ... Theranostics 12 (15), 6705, 2022 | 11 | 2022 |
Photoreceptor survival is regulated by GSTO1-1 in the degenerating retina N Fernando, Y Wooff, R Aggio-Bruce, JA Chu-Tan, H Jiao, C Dietrich, ... Investigative ophthalmology & visual science 59 (11), 4362-4374, 2018 | 11 | 2018 |
Anti-inflammatory and neuroprotective properties of the corticosteroid fludrocortisone in retinal degeneration T Racic, A Chang, N Fernando, A Brandli, R Natoli, P Penfold, JM Provis, ... Experimental Eye Research 212, 108765, 2021 | 10 | 2021 |
A method for gene knockdown in the retina using a lipid-based carrier JA Chu-Tan, N Fernando, R Aggio-Bruce, AV Cioanca, K Valter, ... Molecular vision 26, 48, 2020 | 10 | 2020 |