A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ... Cell 146 (5), 732-745, 2011 | 279 | 2011 |
Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity M Stratton, IH Lee, M Bhattacharyya, SM Christensen, LH Chao, ... Elife 3, e01610, 2014 | 117 | 2014 |
Molecular mechanism of activation-triggered subunit exchange in Ca2+/calmodulin-dependent protein kinase II M Bhattacharyya, MM Stratton, CC Going, ED McSpadden, Y Huang, ... Elife 5, e13405, 2016 | 113 | 2016 |
Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II MM Stratton, LH Chao, H Schulman, J Kuriyan Current opinion in structural biology 23 (2), 292-301, 2013 | 104 | 2013 |
Reciprocal activation within a kinase-effector complex underlying persistence of structural LTP T Saneyoshi, H Matsuno, A Suzuki, H Murakoshi, NG Hedrick, E Agnello, ... Neuron 102 (6), 1199-1210. e6, 2019 | 98 | 2019 |
A Ca2+-Sensing Molecular Switch Based on Alternate Frame Protein Folding MM Stratton, DM Mitrea, SN Loh ACS chemical biology 3 (11), 723-732, 2008 | 62 | 2008 |
Converting a protein into a switch for biosensing and functional regulation MM Stratton, SN Loh Protein Science 20 (1), 19-29, 2011 | 59 | 2011 |
Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation R Sloutsky, N Dziedzic, MJ Dunn, RM Bates, AP Torres-Ocampo, ... Science signaling 13 (641), eaaz0240, 2020 | 34 | 2020 |
Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif MS Eriksen, O Nikolaienko, EI Hallin, S Grødem, HJ Bustad, MI Flydal, ... The FEBS journal 288 (9), 2930-2955, 2021 | 31 | 2021 |
Functional implications of CaMKII alternative splicing R Sloutsky, MM Stratton European Journal of Neuroscience 54 (8), 6780-6794, 2021 | 26 | 2021 |
Characterization of CaMKIIα holoenzyme stability AP Torres‐Ocampo, C Özden, A Hommer, A Gardella, E Lapinskas, ... Protein Science 29 (6), 1524-1534, 2020 | 26 | 2020 |
On the mechanism of protein fold‐switching by a molecular sensor MM Stratton, SN Loh Proteins: Structure, Function, and Bioinformatics 78 (16), 3260-3269, 2010 | 26 | 2010 |
CaMKII binds both substrates and activators at the active site C Özden, R Sloutsky, T Mitsugi, N Santos, E Agnello, C Gaubitz, J Foster, ... Cell reports 40 (2), 2022 | 20 | 2022 |
FRET-based sensor for CaMKII activity (FRESCA): a useful tool for assessing CaMKII activity in response to Ca2+ oscillations in live cells G Ardestani, MC West, TJ Maresca, RA Fissore, MM Stratton Journal of Biological Chemistry 294 (31), 11876-11891, 2019 | 17 | 2019 |
Structural Characterization of Two Alternate Conformations in a Calbindin D9k-Based Molecular Switch MM Stratton, S McClendon, D Eliezer, SN Loh Biochemistry 50 (25), 5583-5589, 2011 | 11 | 2011 |
Polymer-based microfluidic device for on-chip counter-diffusive crystallization and in situ X-ray crystallography at room temperature S Saha, C Özden, A Samkutty, S Russi, A Cohen, MM Stratton, SL Perry Lab on a Chip 23 (8), 2075-2090, 2023 | 9 | 2023 |
Probing local structural fluctuations in myoglobin by size‐dependent thiol‐disulfide exchange MM Stratton, TA Cutler, JH Ha, SN Loh Protein Science 19 (8), 1587-1594, 2010 | 9 | 2010 |
Live-cell FLIM-FRET using a commercially available system CM Castellani, AP Torres-Ocampo, J Breffke, AB White, JJ Chambers, ... Methods in cell biology 158, 63-89, 2020 | 6 | 2020 |
Role of CAMK2D in neurodevelopment and associated conditions PMF Rigter, C de Konink, MJ Dunn, MP Onori, JB Humberson, M Thomas, ... The American Journal of Human Genetics 111 (2), 364-382, 2024 | 4 | 2024 |
Molecular determinants of Arc oligomerization and formation of virus-like capsids MS Eriksen, O Nikolaienko, EI Hallin, S Grødem, HJ Bustad, MI Flydal, ... bioRxiv, 667956, 2019 | 4 | 2019 |