Astrocytes from familial and sporadic ALS patients are toxic to motor neurons AM Haidet-Phillips, ME Hester, CJ Miranda, K Meyer, L Braun, A Frakes, ... Nature biotechnology 29 (9), 824-828, 2011 | 935 | 2011 |
Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes ME Hester, MJ Murtha, SW Song, M Rao, CJ Miranda, K Meyer, J Tian, ... Molecular therapy 19 (10), 1905-1912, 2011 | 231 | 2011 |
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis TM Miller, SH Kim, K Yamanaka, M Hester, P Umapathi, H Arnson, L Rizo, ... Proceedings of the National Academy of Sciences 103 (51), 19546-19551, 2006 | 197 | 2006 |
Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity JC Dodge, AM Haidet, W Yang, MA Passini, M Hester, J Clarke, ... Molecular Therapy 16 (6), 1056-1064, 2008 | 180 | 2008 |
Aging brain microenvironment decreases hippocampal neurogenesis through Wnt‐mediated survivin signaling CJ Miranda, L Braun, Y Jiang, ME Hester, L Zhang, M Riolo, H Wang, ... Aging cell 11 (3), 542-552, 2012 | 174 | 2012 |
AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice JC Dodge, CM Treleaven, JA Fidler, M Hester, A Haidet, C Handy, M Rao, ... Molecular therapy 18 (12), 2075-2084, 2010 | 142 | 2010 |
Short-read, high-throughput sequencing technology for STR genotyping DM Bornman, ME Hester, JM Schuetter, MD Kasoji, A Minard-Smith, ... BioTechniques. Rapid Dispatches 2012, 1, 2012 | 129 | 2012 |
Electrophysiological maturation of cerebral organoids correlates with dynamic morphological and cellular development SR Fair, D Julian, AM Hartlaub, ST Pusuluri, G Malik, TL Summerfied, ... Stem cell reports 15 (4), 855-868, 2020 | 113 | 2020 |
Two factor reprogramming of human neural stem cells into pluripotency ME Hester, SW Song, CJ Miranda, A Eagle, PH Schwartz, BK Kaspar PloS one 4 (9), e7044, 2009 | 91 | 2009 |
Maternal high fat diet exposure is associated with increased hepcidin levels, decreased myelination, and neurobehavioral changes in male offspring AE Graf, SW Lallier, G Waidyaratne, MD Thompson, TE Tipple, ME Hester, ... Brain, behavior, and immunity 58, 369-378, 2016 | 76 | 2016 |
AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS ME Hester, KD Foust, RW Kaspar, BK Kaspar Current gene therapy 9 (5), 428-433, 2009 | 68 | 2009 |
Smad2 and Smad3 coordinately regulate craniofacial and endodermal development Y Liu, M Festing, JC Thompson, M Hester, S Rankin, HM El-Hodiri, ... Developmental biology 270 (2), 411-426, 2004 | 68 | 2004 |
Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms MC An, W Lin, J Yang, B Dominguez, D Padgett, Y Sugiura, P Aryal, ... Proceedings of the National Academy of Sciences 107 (23), 10702-10707, 2010 | 52 | 2010 |
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease S Chen, Y Chang, L Li, D Acosta, Y Li, Q Guo, C Wang, E Turkes, ... Acta Neuropathologica Communications 10 (1), 188, 2022 | 47 | 2022 |
Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: Focus on Alzheimer’s disease L Venkataraman, SR Fair, CA McElroy, ME Hester, H Fu Stem cell reviews and reports, 1-22, 2020 | 44 | 2020 |
Smad1 and Smad8 function similarly in mammalian central nervous system development M Hester, JC Thompson, J Mills, Y Liu, HM El-Hodiri, M Weinstein Molecular and cellular biology, 2005 | 40 | 2005 |
Generation of novel conditional and hypomorphic alleles of the Smad2 gene Y Liu, MH Festing, M Hester, JC Thompson, M Weinstein genesis 40 (2), 118-123, 2004 | 39 | 2004 |
Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma S Rajendran, Y Hu, A Canella, C Peterson, A Gross, M Cam, M Nazzaro, ... Cell reports 42 (3), 2023 | 29 | 2023 |
PTEN somatic mutations contribute to spectrum of cerebral overgrowth DC Koboldt, KE Miller, AR Miller, JM Bush, S McGrath, K Leraas, E Crist, ... Brain 144 (10), 2971-2978, 2021 | 29 | 2021 |
AUTS2 syndrome: molecular mechanisms and model systems A Biel, AS Castanza, R Rutherford, SR Fair, L Chifamba, JC Wester, ... Frontiers in molecular neuroscience 15, 858582, 2022 | 25 | 2022 |