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Mark Hester
Mark Hester
Assistant Professor at the Institute for Genomic Medicine, Nationwide Children's Hospital
在 nationwidechildrens.org 的电子邮件经过验证
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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
AM Haidet-Phillips, ME Hester, CJ Miranda, K Meyer, L Braun, A Frakes, ...
Nature biotechnology 29 (9), 824-828, 2011
9352011
Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes
ME Hester, MJ Murtha, SW Song, M Rao, CJ Miranda, K Meyer, J Tian, ...
Molecular therapy 19 (10), 1905-1912, 2011
2312011
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis
TM Miller, SH Kim, K Yamanaka, M Hester, P Umapathi, H Arnson, L Rizo, ...
Proceedings of the National Academy of Sciences 103 (51), 19546-19551, 2006
1972006
Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity
JC Dodge, AM Haidet, W Yang, MA Passini, M Hester, J Clarke, ...
Molecular Therapy 16 (6), 1056-1064, 2008
1802008
Aging brain microenvironment decreases hippocampal neurogenesis through Wnt‐mediated survivin signaling
CJ Miranda, L Braun, Y Jiang, ME Hester, L Zhang, M Riolo, H Wang, ...
Aging cell 11 (3), 542-552, 2012
1742012
AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice
JC Dodge, CM Treleaven, JA Fidler, M Hester, A Haidet, C Handy, M Rao, ...
Molecular therapy 18 (12), 2075-2084, 2010
1422010
Short-read, high-throughput sequencing technology for STR genotyping
DM Bornman, ME Hester, JM Schuetter, MD Kasoji, A Minard-Smith, ...
BioTechniques. Rapid Dispatches 2012, 1, 2012
1292012
Electrophysiological maturation of cerebral organoids correlates with dynamic morphological and cellular development
SR Fair, D Julian, AM Hartlaub, ST Pusuluri, G Malik, TL Summerfied, ...
Stem cell reports 15 (4), 855-868, 2020
1132020
Two factor reprogramming of human neural stem cells into pluripotency
ME Hester, SW Song, CJ Miranda, A Eagle, PH Schwartz, BK Kaspar
PloS one 4 (9), e7044, 2009
912009
Maternal high fat diet exposure is associated with increased hepcidin levels, decreased myelination, and neurobehavioral changes in male offspring
AE Graf, SW Lallier, G Waidyaratne, MD Thompson, TE Tipple, ME Hester, ...
Brain, behavior, and immunity 58, 369-378, 2016
762016
AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS
ME Hester, KD Foust, RW Kaspar, BK Kaspar
Current gene therapy 9 (5), 428-433, 2009
682009
Smad2 and Smad3 coordinately regulate craniofacial and endodermal development
Y Liu, M Festing, JC Thompson, M Hester, S Rankin, HM El-Hodiri, ...
Developmental biology 270 (2), 411-426, 2004
682004
Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms
MC An, W Lin, J Yang, B Dominguez, D Padgett, Y Sugiura, P Aryal, ...
Proceedings of the National Academy of Sciences 107 (23), 10702-10707, 2010
522010
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease
S Chen, Y Chang, L Li, D Acosta, Y Li, Q Guo, C Wang, E Turkes, ...
Acta Neuropathologica Communications 10 (1), 188, 2022
472022
Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: Focus on Alzheimer’s disease
L Venkataraman, SR Fair, CA McElroy, ME Hester, H Fu
Stem cell reviews and reports, 1-22, 2020
442020
Smad1 and Smad8 function similarly in mammalian central nervous system development
M Hester, JC Thompson, J Mills, Y Liu, HM El-Hodiri, M Weinstein
Molecular and cellular biology, 2005
402005
Generation of novel conditional and hypomorphic alleles of the Smad2 gene
Y Liu, MH Festing, M Hester, JC Thompson, M Weinstein
genesis 40 (2), 118-123, 2004
392004
Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma
S Rajendran, Y Hu, A Canella, C Peterson, A Gross, M Cam, M Nazzaro, ...
Cell reports 42 (3), 2023
292023
PTEN somatic mutations contribute to spectrum of cerebral overgrowth
DC Koboldt, KE Miller, AR Miller, JM Bush, S McGrath, K Leraas, E Crist, ...
Brain 144 (10), 2971-2978, 2021
292021
AUTS2 syndrome: molecular mechanisms and model systems
A Biel, AS Castanza, R Rutherford, SR Fair, L Chifamba, JC Wester, ...
Frontiers in molecular neuroscience 15, 858582, 2022
252022
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