A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS M McMahon, A Contreras, M Holm, T Uechi, CM Forester, X Pang, ... Elife 8, e48847, 2019 | 114 | 2019 |
Comprehensive analysis of stop codon usage in bacteria and its correlation with release factor abundance G Korkmaz, M Holm, T Wiens, S Sanyal Journal of Biological Chemistry 289 (44), 30334-30342, 2014 | 106 | 2014 |
tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis J Flis, M Holm, EJ Rundlet, J Loerke, T Hilal, M Dabrowski, J Bürger, ... Cell reports 25 (10), 2676-2688. e7, 2018 | 77 | 2018 |
Structural basis of early translocation events on the ribosome EJ Rundlet, M Holm, M Schacherl, SK Natchiar, RB Altman, CMT Spahn, ... Nature 595 (7869), 741-745, 2021 | 75 | 2021 |
Molecular mechanism of viomycin inhibition of peptide elongation in bacteria M Holm, A Borg, M Ehrenberg, S Sanyal Proceedings of the National Academy of Sciences 113 (4), 978-983, 2016 | 53 | 2016 |
Fusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome A Borg, M Holm, I Shiroyama, V Hauryliuk, M Pavlov, S Sanyal, ... Journal of Biological Chemistry 290 (6), 3440-3454, 2015 | 46 | 2015 |
Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection JC Morse, D Girodat, BJ Burnett, M Holm, RB Altman, KY Sanbonmatsu, ... Proceedings of the National Academy of Sciences 117 (7), 3610-3620, 2020 | 44 | 2020 |
A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate RK Koripella, M Holm, D Dourado, CS Mandava, S Flores, S Sanyal Scientific reports 5 (1), 1-10, 2015 | 33 | 2015 |
mRNA decoding in human is kinetically and structurally distinct from bacteria M Holm, SK Natchiar, EJ Rundlet, AG Myasnikov, ZL Watson, RB Altman, ... Nature, 1-8, 2023 | 28 | 2023 |
Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome S Pellegrino, M Meyer, ZA Könst, M Holm, VK Voora, D Kashinskaya, ... Nucleic acids research 47 (6), 3223-3232, 2019 | 20 | 2019 |
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes MF Juette, JD Carelli, EJ Rundlet, A Brown, S Shao, A Ferguson, ... Elife 11, e81608, 2022 | 16 | 2022 |
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3 HY Wang, H Yang, M Holm, H Tom, K Oltion, AAQ Al-Khdhairawi, ... Nature Chemistry, 1-8, 2022 | 15 | 2022 |
The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation M Holm, CS Mandava, M Ehrenberg, S Sanyal eLife 8, e46124, 2019 | 14 | 2019 |
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation M Wieland, M Holm, EJ Rundlet, M Morici, TO Koller, TP Maviza, ... Proceedings of the National Academy of Sciences 119 (19), e2114214119, 2022 | 11 | 2022 |
Hyper-swivel head domain motions are required for complete mRNA-tRNA translocation and ribosome resetting W Nishima, D Girodat, M Holm, EJ Rundlet, JL Alejo, K Fischer, ... Nucleic Acids Research, 2022 | 7 | 2022 |
Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation C Kim, M Holm, CS Mandava, S Sanyal RNA biology, 1-13, 2021 | 5 | 2021 |
A tale of two antibiotics: Fusidic acid and Viomycin M Holm Acta Universitatis Upsaliensis, 2016 | | 2016 |