Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients EE Smith, DG Buckley, Z Wu, C Saenphimmachak, LR Hoffman, ... Proceedings of the National Academy of Sciences 103 (22), 8487-8492, 2006 | 1623 | 2006 |
Aminoglycoside antibiotics induce bacterial biofilm formation LR Hoffman, DA D'Argenio, MJ MacCoss, Z Zhang, RA Jones, SI Miller Nature 436 (7054), 1171-1175, 2005 | 1620 | 2005 |
Virus-cell and cell-cell fusion LD Hernandez, LR Hoffman, TG Wolfsberg, JM White Annual review of cell and developmental biology 12 (1), 627-661, 1996 | 776 | 1996 |
Failure to recover to baseline pulmonary function after cystic fibrosis pulmonary exacerbation DB Sanders, RCL Bittner, M Rosenfeld, LR Hoffman, GJ Redding, ... American journal of respiratory and critical care medicine 182 (5), 627-632, 2010 | 580 | 2010 |
Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa LR Hoffman, E Déziel, DA d'Argenio, F Lépine, J Emerson, S McNamara, ... Proceedings of the National Academy of Sciences 103 (52), 19890-19895, 2006 | 516 | 2006 |
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients DA D'Argenio, M Wu, LR Hoffman, HD Kulasekara, E Déziel, EE Smith, ... Molecular microbiology 64 (2), 512-533, 2007 | 423 | 2007 |
Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ... American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017 | 365 | 2017 |
Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression LR Hoffman, HD Kulasekara, J Emerson, LS Houston, JL Burns, ... Journal of Cystic Fibrosis 8 (1), 66-70, 2009 | 337 | 2009 |
Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell division M Christen, HD Kulasekara, B Christen, BR Kulasekara, LR Hoffman, ... Science 328 (5983), 1295-1297, 2010 | 333 | 2010 |
LasR variant cystic fibrosis isolates reveal an adaptable quorum-sensing hierarchy in Pseudomonas aeruginosa JB Feltner, DJ Wolter, CE Pope, MC Groleau, NE Smalley, EP Greenberg, ... MBio 7 (5), 10.1128/mbio. 01513-16, 2016 | 227 | 2016 |
Clinical effectiveness of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis: a clinical trial DP Nichols, AC Paynter, SL Heltshe, SH Donaldson, CA Frederick, ... American journal of respiratory and critical care medicine 205 (5), 529-539, 2022 | 219 | 2022 |
Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease in Children With Cystic Fibrosis DJ Wolter, JC Emerson, S McNamara, AM Buccat, X Qin, E Cochrane, ... Clinical Infectious Diseases 57 (3), 384-391, 2013 | 199 | 2013 |
Lung function and microbiota diversity in cystic fibrosis L Cuthbertson, AW Walker, AE Oliver, GB Rogers, DW Rivett, ... Microbiome 8, 1-13, 2020 | 196 | 2020 |
The microbiota in bronchoalveolar lavage from young children with chronic lung disease includes taxa present in both the oropharynx and nasopharynx RL Marsh, M Kaestli, AB Chang, MJ Binks, CE Pope, LR Hoffman, ... Microbiome 4, 1-18, 2016 | 184 | 2016 |
Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resilience FA Stressmann, GB Rogers, CJ Van Der Gast, P Marsh, LS Vermeer, ... Thorax 67 (10), 867-873, 2012 | 166 | 2012 |
Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation? FA Stressmann, GB Rogers, P Marsh, AK Lilley, TWV Daniels, MP Carroll, ... Journal of Cystic Fibrosis 10 (5), 357-365, 2011 | 159 | 2011 |
Nutrient Availability as a Mechanism for Selection of Antibiotic Tolerant Pseudomonas aeruginosa within the CF Airway LR Hoffman, AR Richardson, LS Houston, HD Kulasekara, ... PLoS pathogens 6 (1), e1000712, 2010 | 152 | 2010 |
Return of FEV1 after pulmonary exacerbation in children with cystic fibrosis DB Sanders, LR Hoffman, J Emerson, RL Gibson, M Rosenfeld, ... Pediatric pulmonology 45 (2), 127-134, 2010 | 150 | 2010 |
Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: irreversible inhibition of infectivity LR Hoffman, ID Kuntz, JM White Journal of Virology 71 (11), 8808-8820, 1997 | 144 | 1997 |
Pseudomonas aeruginosa in vitro phenotypes distinguish cystic fibrosis infection stages and outcomes N Mayer-Hamblett, M Rosenfeld, RL Gibson, BW Ramsey, HD Kulasekara, ... American journal of respiratory and critical care medicine 190 (3), 289-297, 2014 | 135 | 2014 |