Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κB and the serine/threonine kinase Akt and is independent of tubulin polymerization SV Bava, VT Puliappadamba, A Deepti, A Nair, D Karunagaran, RJ Anto Journal of Biological Chemistry 280 (8), 6301-6308, 2005 | 270 | 2005 |
Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil BS Vinod, J Antony, HH Nair, VT Puliyappadamba, M Saikia, ... Cell death & disease 4 (2), e505-e505, 2013 | 141 | 2013 |
Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks S Chakraborty, L Li, VT Puliyappadamba, G Guo, KJ Hatanpaa, B Mickey, ... Nature communications 5 (1), 5811, 2014 | 101 | 2014 |
Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism SV Bava, CN Sreekanth, AKT Thulasidasan, NP Anto, VT Cheriyan, ... The international journal of biochemistry & cell biology 43 (3), 331-341, 2011 | 101 | 2011 |
The role of NF-κB in the pathogenesis of glioma VT Puliyappadamba, KJ Hatanpaa, S Chakraborty, AA Habib Molecular & cellular oncology 1 (3), e963478, 2014 | 93 | 2014 |
A novel protein fraction from Sesbania grandiflora shows potential anticancer and chemopreventive efficacy, in vitro and in vivo KP Laladhas, VT Cheriyan, VT Puliappadamba, SV Bava, RG Unnithan, ... Journal of cellular and molecular medicine 14 (3), 636-646, 2010 | 90 | 2010 |
Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent VT Puliyappadamba, VT Cheriyan, AKT Thulasidasan, SV Bava, ... Molecular cancer 9, 1-15, 2010 | 63 | 2010 |
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma DDSMRSMMLACWJEECEBJBSASMSRYFLVTPWGJKLEJHLLGYXMXBHRBJDMBMSMSTDLCGABCSLJMAHIKT ... Cancer cell, 2022 | 62 | 2022 |
Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis VT Puliyappadamba, W Wu, D Bevis, L Zhang, L Polin, R Kilkuskie, ... Journal of Biological Chemistry 286 (44), 38000-38017, 2011 | 55 | 2011 |
Opposing effect of EGFRWT on EGFRvIII-mediated NF-κB activation with RIP1 as a cell death switch VT Puliyappadamba, S Chakraborty, SS Chauncey, L Li, KJ Hatanpaa, ... Cell reports 4 (4), 764-775, 2013 | 54 | 2013 |
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma L Li, VT Puliyappadamba, S Chakraborty, A Rehman, V Vemireddy, ... Oncogene 34 (1), 129-134, 2015 | 49 | 2015 |
Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines Y Wang, AK Rishi, VT Puliyappadamba, S Sharma, H Yang, A Tarca, ... Cancer chemotherapy and pharmacology 66, 455-466, 2010 | 49 | 2010 |
An EGFR wild type–EGFRvIII–HB-EGF feed-forward loop regulates the activation of EGFRvIII L Li, S Chakraborty, CR Yang, KJ Hatanpaa, DJ Cipher, ... Oncogene 33 (33), 4253-4264, 2014 | 47 | 2014 |
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma AAH Gao Guo, Ke Gong, Vineshkumar Thidil Puliyappadamba, Nishah Panchani ... Neuro-Oncology, 2019 | 31 | 2019 |
Curcumin inhibits B [a] PDE‐induced procarcinogenic signals in lung cancer cells, and curbs B [a] P‐induced mutagenesis and lung carcinogenesis VT Puliyappadamba, AKT Thulasidasan, V Vijayakurup, J Antony, ... Biofactors 41 (6), 431-442, 2015 | 30 | 2015 |
A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1 Y Jiang, VT Puliyappadamba, L Zhang, W Wu, A Wali, MB Yaffe, ... Journal of Molecular Signaling 5, 1-12, 2010 | 28 | 2010 |
Cytoplasmic TRADD confers a worse prognosis in glioblastoma S Chakraborty, L Li, H Tang, Y Xie, VT Puliyappadamba, J Raisanen, ... Neoplasia 15 (8), 888-897, 2013 | 17 | 2013 |
Green synthesis of silver NPs using herbal plants KP Laldhas, VT Cheriyan, VT Puliappadamba, SV Bava, RG Unnithan, ... J. Cell Mol. Med 14 (8), 636-646, 2010 | 6 | 2010 |
ATR INHIBITOR VE-822 IS A NOVEL RADIO- SENSITIZER FOR GLIOMA VT Puliyappadamba, M Lou, E Fletcher, V Sadaphal, X Li, RS Mani, ... Neuro-Oncology, 20 (suppl_6), vi224, 2018 | | 2018 |
Targeting of PTBP1 Reverses Lineage Specific Splicing of the Tumor Suppressor ANXA7 and Oncogenic EGFR Signaling in Glioblastoma M Bredel, R Ferrarese, NK Thudi, VKT Puliyappadamba, E Bug, ... International Journal of Radiation Oncology, Biology, Physics 93 (3), S48, 2015 | | 2015 |