The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors SB Willingham, JP Volkmer, AJ Gentles, D Sahoo, P Dalerba, SS Mitra, ... Proceedings of the National Academy of Sciences 109 (17), 6662-6667, 2012 | 1628 | 2012 |
Neuronal activity promotes glioma growth through neuroligin-3 secretion HS Venkatesh, TB Johung, V Caretti, A Noll, Y Tang, S Nagaraja, ... Cell 161 (4), 803-816, 2015 | 699 | 2015 |
CAR T cells targeting B7-H3, a pan-cancer antigen, demonstrate potent preclinical activity against pediatric solid tumors and brain tumors RG Majzner, JL Theruvath, A Nellan, S Heitzeneder, Y Cui, CW Mount, ... Clinical Cancer Research 25 (8), 2560-2574, 2019 | 469 | 2019 |
BET bromodomain inhibition of MYC-amplified medulloblastoma P Bandopadhayay, G Bergthold, B Nguyen, S Schubert, S Gholamin, ... Clinical Cancer Research 20 (4), 912-925, 2014 | 381 | 2014 |
Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors S Gholamin, SS Mitra, AH Feroze, J Liu, SA Kahn, M Zhang, R Esparza, ... Science translational medicine 9 (381), eaaf2968, 2017 | 370 | 2017 |
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma M Monje, SS Mitra, ME Freret, TB Raveh, J Kim, M Masek, JL Attema, G Li, ... Proceedings of the National Academy of Sciences 108 (11), 4453-4458, 2011 | 343 | 2011 |
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition Y Tang, S Gholamin, S Schubert, MI Willardson, A Lee, P Bandopadhayay, ... Nature medicine 20 (7), 732-740, 2014 | 323 | 2014 |
Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo M Zhang, G Hutter, SA Kahn, TD Azad, S Gholamin, CY Xu, J Liu, ... PloS one 11 (4), e0153550, 2016 | 319 | 2016 |
Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk M Feng, JY Chen, R Weissman-Tsukamoto, JP Volkmer, PY Ho, ... Proceedings of the National Academy of Sciences 112 (7), 2145-2150, 2015 | 266 | 2015 |
Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma G Hutter, J Theruvath, CM Graef, M Zhang, MK Schoen, EM Manz, ... Proceedings of the National Academy of Sciences 116 (3), 997-1006, 2019 | 219 | 2019 |
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ... Nature medicine 26 (5), 712-719, 2020 | 213 | 2020 |
Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III DR Emlet, P Gupta, M Holgado-Madruga, CA Del Vecchio, SS Mitra, ... Cancer research 74 (4), 1238-1249, 2014 | 160 | 2014 |
Usp16 contributes to somatic stem-cell defects in Down’s syndrome M Adorno, S Sikandar, SS Mitra, A Kuo, B Nicolis di Robilant, ... Nature 501 (7467), 380-384, 2013 | 143 | 2013 |
A hematogenous route for medulloblastoma leptomeningeal metastases L Garzia, N Kijima, AS Morrissy, P De Antonellis, A Guerreiro-Stucklin, ... Cell 172 (5), 1050-1062. e14, 2018 | 131 | 2018 |
Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway KS Lee, Z Wu, Y Song, SS Mitra, AH Feroze, SH Cheshier, B Lu Genes & development 27 (24), 2642-2647, 2013 | 106 | 2013 |
Nanoparticle enhanced MRI can monitor macrophage response to CD47 mAb immunotherapy in osteosarcoma S Mohanty, K Yerneni, JL Theruvath, CM Graef, H Nejadnik, O Lenkov, ... Cell death & disease 10 (2), 36, 2019 | 88 | 2019 |
Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity A Mitra, SS Mitra, RW Tsien Nature neuroscience 15 (2), 250-257, 2012 | 88 | 2012 |
Development of an EGFRvIII specific recombinant antibody P Gupta, SY Han, M Holgado-Madruga, SS Mitra, G Li, RT Nitta, AJ Wong BMC biotechnology 10, 1-13, 2010 | 82 | 2010 |
Innate immune checkpoint inhibitors: the next breakthrough in medical oncology? RW Lentz, MD Colton, SS Mitra, WA Messersmith Molecular cancer therapeutics 20 (6), 961-974, 2021 | 78 | 2021 |
Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas G Li, SS Mitra, M Monje, KN Henrich, CD Bangs, RT Nitta, AJ Wong Journal of neuro-oncology 108, 395-402, 2012 | 70 | 2012 |