| The acetylation of tau inhibits its function and promotes pathological tau aggregation TJ Cohen, JL Guo, DE Hurtado, LK Kwong, IP Mills, JQ Trojanowski, ... Nature communications 2 (1), 252, 2011 | 767 | 2011 |
| Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies DJ Irwin, TJ Cohen, M Grossman, SE Arnold, SX Xie, VMY Lee, ... Brain 135 (3), 807-818, 2012 | 305 | 2012 |
| An acetylation switch controls TDP-43 function and aggregation propensity TJ Cohen, AW Hwang, CR Restrepo, CX Yuan, JQ Trojanowski, VMY Lee Nature communications 6 (1), 5845, 2015 | 296 | 2015 |
| TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies TJ Cohen, VMY Lee, JQ Trojanowski Trends in molecular medicine 17 (11), 659-667, 2011 | 280 | 2011 |
| Redox signalling directly regulates TDP‐43 via cysteine oxidation and disulphide cross‐linking TJ Cohen, AW Hwang, T Unger, JQ Trojanowski, VMY Lee The EMBO journal 31 (5), 1241-1252, 2012 | 227 | 2012 |
| The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming TJ Cohen, DS Waddell, T Barrientos, Z Lu, G Feng, GA Cox, SC Bodine, ... Journal of Biological Chemistry 282 (46), 33752-33759, 2007 | 221 | 2007 |
| Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway E Kozhemyakina, T Cohen, TP Yao, AB Lassar Molecular and cellular biology, 2009 | 164 | 2009 |
| The microtubule-associated tau protein has intrinsic acetyltransferase activity TJ Cohen, D Friedmann, AW Hwang, R Marmorstein, VMY Lee Nature structural & molecular biology 20 (6), 756-762, 2013 | 162 | 2013 |
| Acetylated tau neuropathology in sporadic and hereditary tauopathies DJ Irwin, TJ Cohen, M Grossman, SE Arnold, E McCarty-Wood, ... The American journal of pathology 183 (2), 344-351, 2013 | 136 | 2013 |
| The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity TJ Cohen, T Barrientos, ZC Hartman, SM Garvey, GA Cox, TP Yao The FASEB Journal 23 (1), 99, 2009 | 106 | 2009 |
| Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation Y Chen, TJ Cohen Journal of biological chemistry 294 (10), 3696-3706, 2019 | 95 | 2019 |
| A dual pathogenic mechanism links tau acetylation to sporadic tauopathy H Trzeciakiewicz, JH Tseng, CM Wander, V Madden, A Tripathy, CX Yuan, ... Scientific reports 7 (1), 44102, 2017 | 95 | 2017 |
| Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program P Wang, CM Wander, CX Yuan, MS Bereman, TJ Cohen Nature communications 8 (1), 82, 2017 | 86 | 2017 |
| A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program MC Choi, TJ Cohen, T Barrientos, B Wang, M Li, BJ Simmons, JS Yang, ... Molecular cell 47 (1), 122-132, 2012 | 79 | 2012 |
| An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline H Trzeciakiewicz, D Ajit, JH Tseng, Y Chen, A Ajit, Z Tabassum, ... Nature communications 11 (1), 5522, 2020 | 72 | 2020 |
| AcK-knowledge reversible acetylation T Cohen, TP Yao Science's STKE 2004 (245), pe42-pe42, 2004 | 68 | 2004 |
| The deacetylase HDAC6 mediates endogenous neuritic tau pathology JH Tseng, L Xie, S Song, Y Xie, L Allen, D Ajit, JS Hong, X Chen, ... Cell reports 20 (9), 2169-2183, 2017 | 65 | 2017 |
| HDAC4 regulates muscle fiber type-specific gene expression programs TJ Cohen, MC Choi, M Kapur, VA Lira, Z Yan, TP Yao Molecules and cells 38 (4), 343-348, 2015 | 55 | 2015 |
| The neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2 TA Bolger, X Zhao, TJ Cohen, CC Tsai, TP Yao Journal of Biological Chemistry 282 (40), 29186-29192, 2007 | 55 | 2007 |
| Intrinsic tau acetylation is coupled to auto-proteolytic tau fragmentation TJ Cohen, BH Constance, AW Hwang, M James, CX Yuan PloS one 11 (7), e0158470, 2016 | 50 | 2016 |
