The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology K Bedard, KH Krause Physiological reviews 87 (1), 245-313, 2007 | 7829 | 2007 |
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation L Serrander, L Cartier, K Bedard, B Banfi, B Lardy, O Plastre, ... Biochemical Journal 406 (1), 105-114, 2007 | 687 | 2007 |
NOX family NADPH oxidases: not just in mammals K Bedard, B Lardy, KH Krause Biochimie 89 (9), 1107-1112, 2007 | 343 | 2007 |
Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57 K Bedard, E Szabo, M Michalak, M Opas International review of cytology 245, 91-121, 2005 | 204 | 2005 |
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation L Serrander, V Jaquet, K Bedard, O Plastre, O Hartley, S Arnaudeau, ... Biochimie 89 (9), 1159-1167, 2007 | 160 | 2007 |
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action V Jaquet, J Marcoux, E Forest, KG Leidal, S McCormick, Y Westermaier, ... British journal of pharmacology 164 (2b), 507-520, 2011 | 144 | 2011 |
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci T Aung, M Ozaki, MC Lee, U Schlötzer-Schrehardt, G Thorleifsson, ... Nature genetics 49 (7), 993-1004, 2017 | 143 | 2017 |
NOX5: from basic biology to signaling and disease K Bedard, V Jaquet, KH Krause Free Radical Biology and Medicine 52 (4), 725-734, 2012 | 141 | 2012 |
Phenotypic overlap between familial exudative vitreoretinopathy and microcephaly, lymphedema, and chorioretinal dysplasia caused by KIF11 mutations JM Robitaille, RM Gillett, MA LeBlanc, D Gaston, M Nightingale, ... JAMA ophthalmology 132 (12), 1393-1399, 2014 | 118 | 2014 |
Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia VL Bentley, CJ Veinotte, DP Corkery, JB Pinder, MA LeBlanc, K Bedard, ... Haematologica 100 (1), 70, 2015 | 106 | 2015 |
Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2 DL Guernsey, H Jiang, SC Evans, M Ferguson, M Matsuoka, ... The American Journal of Human Genetics 85 (1), 120-129, 2009 | 99 | 2009 |
Mutation in the gene encoding ubiquitin ligase LRSAM1 in patients with Charcot-Marie-Tooth disease DL Guernsey, H Jiang, K Bedard, SC Evans, M Ferguson, M Matsuoka, ... PLoS genetics 6 (8), e1001081, 2010 | 82 | 2010 |
Calnexin deficiency leads to dysmyelination A Kraus, J Groenendyk, K Bedard, TA Baldwin, KH Krause, ... Journal of Biological Chemistry 285 (24), 18928-18938, 2010 | 80 | 2010 |
NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression B Li, K Bedard, S Sorce, B Hinz, M Dubois-Dauphin, KH Krause Journal of innate immunity 1 (6), 570-581, 2009 | 78 | 2009 |
Germline Mutations in MAP3K6 Are Associated with Familial Gastric Cancer D Gaston, S Hansford, C Oliveira, M Nightingale, H Pinheiro, ... PLoS genetics 10 (10), e1004669, 2014 | 74 | 2014 |
Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation K Bedard, H Attar, J Bonnefont, V Jaquet, C Borel, O Plastre, MJ Stasia, ... Human mutation 30 (7), 1123-1133, 2009 | 72 | 2009 |
Endoplasmic reticulum stress in the absence of calnexin H Coe, K Bedard, J Groenendyk, J Jung, M Michalak Cell Stress and Chaperones 13, 497-507, 2008 | 65 | 2008 |
Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease LP Bogdanik, JN Sleigh, C Tian, ME Samuels, K Bedard, KL Seburn, ... Disease Models & Mechanisms 6 (3), 780-792, 2013 | 59 | 2013 |
NADPH oxidase 1 deficiency alters Caveolin phosphorylation and angiotensin II–receptor localization in vascular smooth muscle O Basset, C Deffert, M Foti, K Bedard, V Jaquet, E Ogier-Denis, ... Antioxidants & redox signaling 11 (10), 2371-2384, 2009 | 47 | 2009 |
NOX enzymes in immuno-inflammatory pathologies KH Krause, K Bedard Seminars in immunopathology 30, 193-194, 2008 | 46 | 2008 |