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| Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies MA Massiah, C Viragh, PM Reddy, IM Kovach, J Johnson, TL Rosenberry, ... Biochemistry 40 (19), 5682-5690, 2001 | 116 | 2001 |
| Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8 T Lan, ER Kandimalla, D Yu, L Bhagat, Y Li, D Wang, FG Zhu, JX Tang, ... Proceedings of the National Academy of Sciences 104 (34), 13750-13755, 2007 | 106 | 2007 |
| Short, strong hydrogen bonds on enzymes: NMR and mechanistic studies AS Mildvan, MA Massiah, TK Harris, GT Marks, DHT Harrison, C Viragh, ... Journal of molecular structure 615 (1-3), 163-175, 2002 | 81 | 2002 |
| NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase C Viragh, TK Harris, PM Reddy, MA Massiah, AS Mildvan, IM Kovach Biochemistry 39 (51), 16200-16205, 2000 | 72 | 2000 |
| Peptide conjugation at the 5′-end of oligodeoxynucleotides abrogates toll-like receptor 9-mediated immune stimulatory activity MR Putta, FG Zhu, D Wang, L Bhagat, M Dai, ER Kandimalla, S Agrawal Bioconjugate chemistry 21 (1), 39-45, 2010 | 47 | 2010 |
| Toll like receptor modulators E Kandimalla, L Bhagat, M Putta, D Wang, S Agrawal US Patent 8,853,375, 2014 | 39 | 2014 |
| Immunostimulatory activity of immune modulatory oligonucleotides (IMO™) containing different lengths of palindromic segments ER Kandimalla, MR Putta, S Agrawal US Patent 7,786,089, 2010 | 37 | 2010 |
| Novel oligonucleotides containing two 3′-ends complementary to target mRNA show optimal gene-silencing activity L Bhagat, MR Putta, D Wang, D Yu, T Lan, W Jiang, Z Sun, H Wang, ... Journal of medicinal chemistry 54 (8), 3027-3036, 2011 | 36 | 2011 |
| Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) oligonucleotide mixed sequences PM Reddy, TC Bruice Bioorganic & medicinal chemistry letters 13 (7), 1281-1285, 2003 | 36 | 2003 |
| Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) tethering a Hoechst 33258 analogue: triplex and duplex stabilization by simultaneous minor groove binding PM Reddy, TC Bruice Journal of the American Chemical Society 126 (12), 3736-3747, 2004 | 35 | 2004 |
| Compositions for inhibiting gene expression and uses thereof S Agrawal, E Kandimalla, M Putta, T Lan, L Bhagat, D Wang, D Yu US Patent 8,431,544, 2013 | 33 | 2013 |
| Toll-like receptor 7 selective synthetic oligoribonucleotide agonists: Synthesis and structure− activity relationship studies T Lan, M Dai, D Wang, FG Zhu, ER Kandimalla, S Agrawal Journal of medicinal chemistry 52 (21), 6871-6879, 2009 | 32 | 2009 |
| Impact of secondary structure of toll-like receptor 9 agonists on interferon alpha induction D Yu, MR Putta, L Bhagat, M Dai, D Wang, AF Trombino, T Sullivan, ... Antimicrobial agents and chemotherapy 52 (12), 4320-4325, 2008 | 32 | 2008 |
| Sequence selective recognition in the minor groove of dsDNA by pyrrole, imidazole-substituted bis-benzimidazole conjugates PM Reddy, PT Jindra, AL Satz, TC Bruice Journal of the American Chemical Society 125 (26), 7843-7848, 2003 | 31 | 2003 |
| Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 ER Kandimalla, T Lan, Y Li, D Yu, D Wang, MR Putta, S Agrawal US Patent 8,106,173, 2012 | 30 | 2012 |
| Novel oligodeoxynucleotide agonists of TLR9 containing N3-Me-dC or N1-Me-dG modifications MR Putta, FG Zhu, Y Li, L Bhagat, YP Cong, ER Kandimalla, S Agrawal Nucleic acids research 34 (11), 3231-3238, 2006 | 29 | 2006 |
| Synthetic oligoribonucleotides-containing secondary structures act as agonists of Toll-like receptors 7 and 8 T Lan, MR Putta, D Wang, M Dai, D Yu, ER Kandimalla, S Agrawal Biochemical and biophysical research communications 386 (3), 443-448, 2009 | 28 | 2009 |
| Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs D Yu, MR Putta, L Bhagat, Y Li, FG Zhu, D Wang, JX Tang, ER Kandimalla, ... Journal of medicinal chemistry 50 (25), 6411-6418, 2007 | 28 | 2007 |
| Synthetic agonists of TLR9 E Kandimalla, M Putta, D Wang, D Yu, L Bhagat, S Agrawal US Patent 7,960,362, 2011 | 27 | 2011 |
