Centrally acting oximes in reactivation of tabun-phosphoramidated AChE Z Kovarik, N Maček, RK Sit, Z Radić, VV Fokin, KB Sharpless, P Taylor Chemico-biological interactions 203 (1), 77-80, 2013 | 76 | 2013 |
Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration T Zorbaz, A Braïki, N Maraković, J Renou, E de La Mora, N Maček Hrvat, ... Chemistry–A European Journal 24 (38), 9675-9691, 2018 | 68 | 2018 |
Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase … T Zorbaz, D Malinak, N Maraković, N Maček Hrvat, A Zandona, ... Journal of medicinal chemistry 61 (23), 10753-10766, 2018 | 61 | 2018 |
A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers M Katalinić, NM Hrvat, K Baumann, SM Piperčić, S Makarić, S Tomić, ... Toxicology and applied pharmacology 310, 195-204, 2016 | 52 | 2016 |
Catalytic soman scavenging by the Y337A/F338A acetylcholinesterase mutant assisted with novel site-directed aldoximes Z Kovarik, N Maček Hrvat, M Katalinić, RK Sit, A Paradyse, S Žunec, ... Chemical research in toxicology 28 (5), 1036-1044, 2015 | 50 | 2015 |
Pharmacology, pharmacokinetics, and tissue disposition of zwitterionic hydroxyiminoacetamido alkylamines as reactivating antidotes for organophosphate exposure RK Sit, Z Kovarik, NM Hrvat, S Žunec, C Green, VV Fokin, KB Sharpless, ... Journal of Pharmacology and Experimental Therapeutics 367 (2), 363-372, 2018 | 48 | 2018 |
Counteracting poisoning with chemical warfare nerve agents N Maček Hrvat, Z Kovarik Arhiv za higijenu rada i toksikologiju 71 (4), 284-284, 2020 | 43 | 2020 |
Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations M Katalinić, G Šinko, NM Hrvat, T Zorbaz, A Bosak, Z Kovarik Toxicology 406, 104-113, 2018 | 34 | 2018 |
Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning T Zorbaz, P Mišetić, N Probst, S Žunec, A Zandona, G Mendaš, ... ACS chemical neuroscience 11 (7), 1072-1084, 2020 | 33 | 2020 |
The estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation NM Hrvat, T Zorbaz, G Šinko, Z Kovarik Toxicology letters 293, 222-228, 2018 | 33 | 2018 |
Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase Z Kovarik, J Kalisiak, NM Hrvat, M Katalinić, T Zorbaz, S Žunec, C Green, ... Chemistry–A European Journal 25 (16), 4100-4114, 2019 | 31 | 2019 |
HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants NM Hrvat, S Žunec, P Taylor, Z Radić, Z Kovarik Chemico-biological interactions 259, 148-153, 2016 | 27 | 2016 |
Translation of in vitro to in vivo pyridinium oxime potential in tabun poisoning/Translacija učinkovitosti piridinijevih oksima kod trovanja tabunom iz in vitro sustava u in … M Katalinić, NM Hrvat, JŽ Karasová, J Misik, Z Kovarik Archives of Industrial Hygiene and Toxicology 66 (4), 291-298, 2015 | 25 | 2015 |
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases NM Hrvat, J Kalisiak, G Šinko, Z Radić, KB Sharpless, P Taylor, Z Kovarik Toxicology letters 321, 83-89, 2020 | 21 | 2020 |
Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives I Šagud, N Maček Hrvat, A Grgičević, T Čadež, J Hodak, M Dragojević, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 460-467, 2020 | 20 | 2020 |
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents T Zorbaz, D Malinak, T Hofmanova, N Maraković, S Žunec, NM Hrvat, ... European Journal of Medicinal Chemistry 238, 114377, 2022 | 13 | 2022 |
Efficient detoxification of nerve agents by oxime-assisted reactivation of acetylcholinesterase mutants Z Kovarik, NM Hrvat Neuropharmacology 171, 108111, 2020 | 13 | 2020 |
Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase Z Kovarik, NM Hrvat, J Kalisiak, M Katalinić, RK Sit, T Zorbaz, Z Radić, ... Toxicology and applied pharmacology 372, 40-46, 2019 | 12 | 2019 |
Who's in, who's out? Re‐evaluation of lipid raft residents K Mlinac‐Jerkovic, K Ilic, M Zjalić, D Mandić, Ž Debeljak, M Balog, ... Journal of neurochemistry 158 (3), 657-672, 2021 | 8 | 2021 |
Benzobicyclo [3.2. 1] octene derivatives as a new class of cholinesterase inhibitors T Čadež, A Grgičević, R Ahmetović, D Barić, NM Hrvat, Z Kovarik, I Škorić Molecules 25 (21), 4872, 2020 | 8 | 2020 |