Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis TE North, W Goessling, CR Walkley, C Lengerke, KR Kopani, AM Lord, ... Nature 447 (7147), 1007-1011, 2007 | 1281 | 2007 |
Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey R Zeiser, A Burchert, C Lengerke, M Verbeek, K Maas-Bauer, ... Leukemia 29 (10), 2062-2068, 2015 | 597 | 2015 |
Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development MV Jain, AM Paczulla, T Klonisch, FN Dimgba, SB Rao, K Roberg, ... Journal of cellular and molecular medicine 17 (1), 12-29, 2013 | 319 | 2013 |
Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ... Nature 572 (7768), 254-259, 2019 | 315 | 2019 |
Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma C Lengerke, T Fehm, R Kurth, H Neubauer, V Scheble, F Müller, ... BMC cancer 11, 1-10, 2011 | 271 | 2011 |
Histocompatible embryonic stem cells by parthenogenesis K Kim, P Lerou, A Yabuuchi, C Lengerke, K Ng, J West, A Kirby, MJ Daly, ... science 315 (5811), 482-486, 2007 | 269 | 2007 |
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ... Nature medicine 24 (3), 282-291, 2018 | 268 | 2018 |
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway C Lengerke, S Schmitt, TV Bowman, IH Jang, L Maouche-Chretien, ... Cell stem cell 2 (1), 72-82, 2008 | 257 | 2008 |
Zebrafish xenografts as a tool for in vivo studies on human cancer M Konantz, TB Balci, UF Hartwig, G Dellaire, MC André, JN Berman, ... Annals of the New York Academy of Sciences 1266 (1), 124-137, 2012 | 251 | 2012 |
SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer T Wilbertz, P Wagner, K Petersen, AC Stiedl, VJ Scheble, S Maier, ... Modern pathology 24 (7), 944-953, 2011 | 232 | 2011 |
The transcriptional landscape of hematopoietic stem cell ontogeny S McKinney-Freeman, P Cahan, H Li, SA Lacadie, HT Huang, M Curran, ... Cell stem cell 11 (5), 701-714, 2012 | 208 | 2012 |
SOX2 expression associates with stem cell state in human ovarian carcinoma PM Bareiss, A Paczulla, H Wang, R Schairer, S Wiehr, U Kohlhofer, ... Cancer research 73 (17), 5544-5555, 2013 | 177 | 2013 |
GLA/DRST real-world outcome analysis of CAR T-cell therapies for large B-cell lymphoma in Germany WA Bethge, P Martus, M Schmitt, U Holtick, M Subklewe, B von Tresckow, ... Blood, The Journal of the American Society of Hematology 140 (4), 349-358, 2022 | 164 | 2022 |
SOX2 protein biochemistry in stemness, reprogramming, and cancer: the PI3K/AKT/SOX2 axis and beyond T Schaefer, C Lengerke Oncogene 39 (2), 278-292, 2020 | 164 | 2020 |
Invasive pulmonary aspergillosis: frequency and meaning of the “hypodense sign” on unenhanced CT M Horger, H Einsele, U Schumacher, M Wehrmann, H Hebart, ... The British journal of radiology 78 (932), 697-703, 2005 | 162 | 2005 |
Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond–like features R Carapito, M Konantz, C Paillard, Z Miao, A Pichot, MS Leduc, Y Yang, ... The Journal of clinical investigation 127 (11), 4090-4103, 2017 | 160 | 2017 |
Initial CT manifestations of invasive pulmonary aspergillosis in 45 non-HIV immunocompromised patients: association with patient outcome? M Horger, H Hebart, H Einsele, C Lengerke, CD Claussen, R Vonthein, ... European journal of radiology 55 (3), 437-444, 2005 | 139 | 2005 |
Hematopoietic development from human induced pluripotent stem cells C Lengerke, M Grauer, NI Niebuhr, T Riedt, L Kanz, IH Park, GQ Daley Annals of the New York Academy of Sciences 1176 (1), 219-227, 2009 | 132 | 2009 |
SOX2 amplification is a common event in squamous cell carcinomas of different organ sites S Maier, T Wilbertz, M Braun, V Scheble, M Reischl, R Mikut, R Menon, ... Human pathology 42 (8), 1078-1088, 2011 | 127 | 2011 |
In vitro biomimetic engineering of a human hematopoietic niche with functional properties PE Bourgine, T Klein, AM Paczulla, T Shimizu, L Kunz, KD Kokkaliaris, ... Proceedings of the National Academy of Sciences 115 (25), E5688-E5695, 2018 | 119 | 2018 |