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Daniel Christ
Daniel Christ
在 garvan.org.au 的电子邮件经过验证 - 首页
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引用次数
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I-motif DNA structures are formed in the nuclei of human cells
M Zeraati, DB Langley, P Schofield, AL Moye, R Rouet, WE Hughes, ...
Nature chemistry 10 (6), 631-637, 2018
5202018
Selection of human antibody fragments by phage display
CMY Lee, N Iorno, F Sierro, D Christ
Nature protocols 2 (11), 3001-3008, 2007
3262007
Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells
NJ Kräutler, D Suan, D Butt, K Bourne, JR Hermes, TD Chan, C Sundling, ...
The Journal of experimental medicine 214 (5), 1259, 2017
2952017
Challenges and opportunities for non-antibody scaffold drugs
R Vazquez-Lombardi, TG Phan, C Zimmermann, D Lowe, L Jermutus, ...
Drug discovery today 20 (10), 1271-1283, 2015
2912015
Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity
Z Sabouri, P Schofield, K Horikawa, E Spierings, D Kipling, KL Randall, ...
Proceedings of the National Academy of Sciences 111 (25), E2567-E2575, 2014
2772014
General strategy for the generation of human antibody variable domains with increased aggregation resistance
K Dudgeon, R Rouet, I Kokmeijer, P Schofield, J Stolp, D Langley, ...
Proceedings of the National Academy of Sciences 109 (27), 10879-10884, 2012
2212012
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ...
Nature communications 10 (1), 3637, 2019
2192019
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells
D Gatto, K Wood, I Caminschi, D Murphy-Durland, P Schofield, D Christ, ...
Nature immunology 14 (5), 446-453, 2013
2112013
Aggregation, stability, and formulation of human antibody therapeutics
D Lowe, K Dudgeon, R Rouet, P Schofield, L Jermutus, D Christ
Advances in protein chemistry and structural biology 84, 41-61, 2011
2062011
Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer
SA O'Toole, DA Machalek, RF Shearer, EKA Millar, R Nair, P Schofield, ...
Cancer research 71 (11), 4002-4014, 2011
1882011
Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization
JH Reed, J Jackson, D Christ, CC Goodnow
The Journal of experimental medicine 213 (7), 1255, 2016
1642016
Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination
DL Burnett, DB Langley, P Schofield, JR Hermes, TD Chan, J Jackson, ...
Science 360 (6385), 223-226, 2018
1422018
A subset of interleukin-21+ chemokine receptor CCR9+ T helper cells target accessory organs of the digestive system in autoimmunity
HM McGuire, A Vogelzang, CS Ma, WE Hughes, PA Silveira, SG Tangye, ...
Immunity 34 (4), 602-615, 2011
1282011
SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants
F Tea, A Ospina Stella, A Aggarwal, D Ross Darley, D Pilli, D Vitale, ...
PLoS medicine 18 (7), e1003656, 2021
1272021
Thermodynamically stable aggregation-resistant antibody domains through directed evolution
K Famm, L Hansen, D Christ, G Winter
Journal of molecular biology 376 (4), 926-931, 2008
1272008
Stability engineering of the human antibody repertoire
R Rouet, D Lowe, D Christ
FEBS letters 588 (2), 269-277, 2014
1172014
Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody
M Singh, KJL Jackson, JJ Wang, P Schofield, MA Field, D Koppstein, ...
Cell 180 (5), 878-894. e19, 2020
1082020
Transient expression of human antibodies in mammalian cells
R Vazquez-Lombardi, D Nevoltris, A Luthra, P Schofield, C Zimmermann, ...
Nature Protocols 13 (1), 99-117, 2018
1012018
FAS inactivation releases unconventional germinal center B cells that escape antigen control and drive IgE and autoantibody production
D Butt, TD Chan, K Bourne, JR Hermes, A Nguyen, A Statham, ...
Immunity 42 (5), 890-902, 2015
1002015
Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models
HM McGuire, S Walters, A Vogelzang, CMY Lee, KE Webster, J Sprent, ...
Diabetes 60 (3), 867-875, 2011
942011
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