Single-molecule FRET methods to study the dynamics of proteins at work H Mazal, G Haran Current opinion in biomedical engineering 12, 8-17, 2019 | 124 | 2019 |
Direct observation of ultrafast large-scale dynamics of an enzyme under turnover conditions HY Aviram, M Pirchi, H Mazal, Y Barak, I Riven, G Haran Proceedings of the National Academy of Sciences 115 (13), 3243-3248, 2018 | 104 | 2018 |
Two closed ATP-and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn (II) EPR spectroscopic techniques A Giannoulis, A Feintuch, Y Barak, H Mazal, S Albeck, T Unger, F Yang, ... Proceedings of the National Academy of Sciences 117 (1), 395-404, 2020 | 57 | 2020 |
Tunable microsecond dynamics of an allosteric switch regulate the activity of a AAA+ disaggregation machine H Mazal, M Iljina, Y Barak, N Elad, R Rosenzweig, P Goloubinoff, I Riven, ... Nature communications 10 (1), 1438, 2019 | 50 | 2019 |
Self-supervised machine learning pushes the sensitivity limit in label-free detection of single proteins below 10 kDa M Dahmardeh, H Mirzaalian Dastjerdi, H Mazal, H Köstler, V Sandoghdar Nature Methods 20 (3), 442-447, 2023 | 34 | 2023 |
Ultrafast pore-loop dynamics in a AAA+ machine point to a Brownian-ratchet mechanism for protein translocation H Mazal, M Iljina, I Riven, G Haran SCIENCE ADVANCES 7 (36), 2021 | 34* | 2021 |
Long-range charge reorganization as an allosteric control signal in proteins K Banerjee-Ghosh, S Ghosh, H Mazal, I Riven, G Haran, R Naaman Journal of the American Chemical Society 142 (48), 20456-20462, 2020 | 29 | 2020 |
Effect of ligand binding on a protein with a complex folding landscape H Mazal, H Aviram, I Riven, G Haran Physical Chemistry Chemical Physics 20 (5), 3054-3062, 2018 | 26 | 2018 |
How fast are the motions of tertiary-structure elements in proteins? G Haran, H Mazal The Journal of Chemical Physics 153 (13), 2020 | 15 | 2020 |
Measuring protein stability in the GroEL chaperonin cage reveals massive destabilization I Korobko, H Mazal, G Haran, A Horovitz Elife 9, e56511, 2020 | 14 | 2020 |
Entropic inhibition: how the activity of a AAA+ machine is modulated by its substrate-binding domain M Iljina, H Mazal, P Goloubinoff, I Riven, G Haran ACS chemical biology 16 (4), 775-785, 2021 | 12 | 2021 |
Fast dynamics shape the function of the AAA+ machine ClpB: lessons from single‐molecule FRET spectroscopy I Riven, H Mazal, M Iljina, G Haran The FEBS journal 290 (14), 3496-3511, 2023 | 6 | 2023 |
Deciphering a hexameric protein complex with Angstrom optical resolution H Mazal, FF Wieser, V Sandoghdar Elife 11, e76308, 2022 | 6 | 2022 |
Breaking new ground in protein detection: Self-supervised machine learning and iSCAT enable label-free detection of single proteins below 10 kDa M Dahmardeh, HM Dastjerdi, H Mazal, H Köstler, V Sandoghdar Optical Molecular Probes, Imaging and Drug Delivery, JW2A. 3, 2023 | 1 | 2023 |
Lipidic folding pathway of α-Synuclein via a toxic oligomer C Griesinger, V Sant, D Matthes, H Mazal, L Antonschmidt, F Wieser, ... | | 2024 |
Single-molecule FRET probes allosteric effects on protein-translocating pore loops of a AAA+ machine M Iljina, H Mazal, A Dayananda, Z Zhang, G Stan, I Riven, G Haran Biophysical Journal 123 (3), 374-388, 2024 | | 2024 |
Insights into protein structure using cryogenic light microscopy H Mazal, FF Wieser, V Sandoghdar Biochemical Society Transactions 51 (6), 2041-2059, 2023 | | 2023 |
Urea as a Protein LID Opener: Overcoming Substrate Inhibition in Adenylate Kinase by Tuning Conformational Dynamics D Scheerer, HY Aviram, H Mazal, I Riven, G Haran Biophysical Journal 120 (3), 189a, 2021 | | 2021 |
Single-molecule protein dynamics: From ligand binding effects on folding to function-related motions H Mazal Weizmann Institute of Science, 2019 | | 2019 |