| Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: the npde add-on package for R E Comets, K Brendel, F Mentré Computer methods and programs in biomedicine 90 (2), 154-166, 2008 | 492 | 2008 |
| Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide K Brendel, E Comets, C Laffont, C Laveille, F Mentré Pharmaceutical research 23, 2036-2049, 2006 | 377 | 2006 |
| Model evaluation of continuous data pharmacometric models: metrics and graphics THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ... CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017 | 314 | 2017 |
| Timing of antiviral treatment initiation is critical to reduce SARS‐CoV‐2 viral load A Gonçalves, J Bertrand, R Ke, E Comets, X De Lamballerie, D Malvy, ... CPT: pharmacometrics & systems pharmacology 9 (9), 509-514, 2020 | 221 | 2020 |
| Are population pharmacokinetic and/or pharmacodynamic models adequately evaluated? A survey of the literature from 2002 to 2004 K Brendel, C Dartois, E Comets, A Lemenuel-Diot, C Laveille, ... Clinical pharmacokinetics 46, 221-234, 2007 | 215 | 2007 |
| Association of an IRF5 gene functional polymorphism with Sjögren's syndrome C Miceli‐Richard, E Comets, P Loiseau, X Puechal, E Hachulla, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2007 | 211 | 2007 |
| Parameter estimation in nonlinear mixed effect models using saemix, an R implementation of the SAEM algorithm E Comets, A Lavenu, M Lavielle Journal of Statistical Software 80, 1-41, 2017 | 132 | 2017 |
| The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome C Miceli‐Richard, N Gestermann, M Ittah, E Comets, P Loiseau, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 125 | 2009 |
| A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed‐effects models HT Thai, F Mentré, NHG Holford, C Veyrat‐Follet, E Comets Pharmaceutical statistics 12 (3), 129-140, 2013 | 123 | 2013 |
| Design in nonlinear mixed effects models: optimization using the Fedorov–Wynn algorithm and power of the Wald test for binary covariates S Retout, E Comets, A Samson, F Mentré Statistics in Medicine 26 (28), 5162-5179, 2007 | 116 | 2007 |
| Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey C Dartois, K Brendel, E Comets, CM Laffont, C Laveille, B Tranchand, ... British journal of clinical pharmacology 64 (5), 603-612, 2007 | 109 | 2007 |
| Evaluation of different tests based on observations for external model evaluation of population analyses K Brendel, E Comets, C Laffont, F Mentré Journal of pharmacokinetics and pharmacodynamics 37, 49-65, 2010 | 106 | 2010 |
| A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis C Miceli-Richard, E Comets, C Verstuyft, R Tamouza, P Loiseau, ... Annals of the rheumatic diseases 67 (4), 478-484, 2008 | 103 | 2008 |
| New colistin population pharmacokinetic data in critically ill patients suggesting an alternative loading dose rationale N Grégoire, O Mimoz, B Mégarbane, E Comets, D Chatelier, S Lasocki, ... Antimicrobial agents and chemotherapy 58 (12), 7324-7330, 2014 | 100 | 2014 |
| Cerebral uptake of mefloquine enantiomers with and without the P‐gp inhibitor elacridar (GF1210918) in mice SB De Lagerie, E Comets, C Gautrand, C Fernandez, D Auchere, ... British journal of pharmacology 141 (7), 1214-1222, 2004 | 87 | 2004 |
| STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling N Gestermann, A Mekinian, E Comets, P Loiseau, X Puechal, E Hachulla, ... Genes & Immunity 11 (5), 432-438, 2010 | 85 | 2010 |
| Evaluation of bootstrap methods for estimating uncertainty of parameters in nonlinear mixed-effects models: a simulation study in population pharmacokinetics HT Thai, F Mentré, NHG Holford, C Veyrat-Follet, E Comets Journal of pharmacokinetics and pharmacodynamics 41, 15-33, 2014 | 81 | 2014 |
| Population pharmacokinetic-pharmacogenetic study of nevirapine in HIV-infected Cambodian patients M Chou, J Bertrand, O Segeral, C Verstuyft, L Borand, E Comets, ... Antimicrobial agents and chemotherapy 54 (10), 4432-4439, 2010 | 61 | 2010 |
| Dose‐finding methods for phase I clinical trials using pharmacokinetics in small populations M Ursino, S Zohar, F Lentz, C Alberti, T Friede, N Stallard, E Comets Biometrical Journal 59 (4), 804-825, 2017 | 57 | 2017 |
| Comparison of model-based tests and selection strategies to detect genetic polymorphisms influencing pharmacokinetic parameters J Bertrand, E Comets, F Mentre Journal of biopharmaceutical statistics 18 (6), 1084-1102, 2008 | 56 | 2008 |
