| Modulation of mRNA stability as a novel therapeutic approach W Eberhardt, A Doller, ES Akool, J Pfeilschifter Pharmacology & therapeutics 114 (1), 56-73, 2007 | 212 | 2007 |
| Nitric oxide increases the decay of matrix metalloproteinase 9 mRNA by inhibiting the expression of mRNA-stabilizing factor HuR ES Akool, H Kleinert, FMA Hamada, MH Abdelwahab, U Fürstermann, ... Molecular and cellular biology 23 (14), 4901-4916, 2003 | 202 | 2003 |
| Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cδ elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase … A Doller, ES Akool, A Huwiler, R Müller, HH Radeke, J Pfeilschifter, ... Molecular and cellular biology 28 (8), 2608-2625, 2008 | 200 | 2008 |
| Molecular mechanisms of TGFβ receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506 ES Akool, A Doller, A Babelova, W Tsalastra, K Moreth, L Schaefer, ... The Journal of Immunology 181 (4), 2831-2845, 2008 | 102 | 2008 |
| ATP potentiates interleukin-1β-induced MMP-9 expression in mesangial cells via recruitment of the ELAV protein HuR A Huwiler, ES Akool, A Aschrafi, FMA Hamada, J Pfeilschifter, ... Journal of Biological Chemistry 278 (51), 51758-51769, 2003 | 97 | 2003 |
| Nitric oxide induces TIMP-1 expression by activating the transforming growth factor β-Smad signaling pathway ES Akool, A Doller, R Muller, P Gutwein, C Xin, A Huwiler, J Pfeilschifter, ... Journal of biological chemistry 280 (47), 39403-39416, 2005 | 75 | 2005 |
| Inhibition of cytokine-induced matrix metalloproteinase 9 expression by peroxisome proliferator-activated receptor α agonists is indirect and due to a NO-mediated reduction of … W Eberhardt, ELS Akool, S Frank, KF Beck, R Franzen, FMA Hamada, ... Journal of biological chemistry 277 (36), 33518-33528, 2002 | 74 | 2002 |
| Rapamycin induces the TGFβ1/Smad signaling cascade in renal mesangial cells upstream of mTOR B Osman, A Doller, ES Akool, M Holdener, E Hintermann, J Pfeilschifter, ... Cellular signalling 21 (12), 1806-1817, 2009 | 56 | 2009 |
| Vitamin E inhibits cyclosporin A-induced CTGF and TIMP-1 expression by repressing ROS-mediated activation of TGF-β/Smad signaling pathway in rat liver A Balah, O Ezzat, ES Akool International immunopharmacology 65, 493-502, 2018 | 46 | 2018 |
| Cyclosporin A and tacrolimus induce renal Erk1/2 pathway via ROS-induced and metalloproteinase-dependent EGF-receptor signaling ES Akool, S Gauer, B Osman, A Doller, S Schulz, H Geiger, J Pfeilschifter, ... Biochemical pharmacology 83 (2), 286-295, 2012 | 40 | 2012 |
| Molecular mechanisms of the protective role of wheat germ oil against cyclosporin A-induced hepatotoxicity in rats ES Akool Pharmaceutical biology 53 (9), 1311-1317, 2015 | 39 | 2015 |
| Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease–antiprotease system by the mTOR inhibitor rapamycin B Osman, ES Akool, A Doller, R Müller, J Pfeilschifter, W Eberhardt Biochemical pharmacology 81 (1), 134-143, 2011 | 38 | 2011 |
| Molecular mechanisms of nitric oxide‐dependent inhibition of TPA‐induced matrix metalloproteinase‐9 (MMP‐9) in MCF‐7 cells C Jespersen, A Doller, ES Akool, M Bachmann, R Müller, P Gutwein, ... Journal of cellular physiology 219 (2), 276-287, 2009 | 36 | 2009 |
| Molecular mechanisms of cyclosporin A inhibition of the cytokine-induced matrix metalloproteinase-9 in glomerular mesangial cells A Doller, ES Akool, R Müller, P Gutwein, C Kurowski, J Pfeilschifter, ... Journal of the American Society of Nephrology 18 (2), 581-592, 2007 | 30 | 2007 |
| Propolis alleviates concanavalin A-induced hepatitis by modulating cytokine secretion and inhibition of reactive oxygen species F Mounieb, L Ramadan, ES Akool, A Balah Naunyn-Schmiedeberg's archives of pharmacology 390, 1105-1115, 2017 | 28 | 2017 |
| The potential antifibrotic impact of apocynin and alpha-lipoic acid in concanavalin A-induced liver fibrosis in rats: Role of NADPH oxidases 1 and 4 MR Fayed, RN El-Naga, ES Akool, E El-Demerdash Drug Discoveries & Therapeutics 12 (2), 58-67, 2018 | 24 | 2018 |
| All-trans retinoic acid potentiates cisplatin-induced kidney injury in rats: impact of retinoic acid signaling pathway AM Elsayed, TM Abdelghany, ES Akool, AAH Abdel-Aziz, ... Naunyn-Schmiedeberg's archives of pharmacology 389, 327-337, 2016 | 16 | 2016 |
| Dissociated glucocorticoids equipotently inhibit cytokine-and cAMP-induced matrix degrading proteases in rat mesangial cells W Eberhardt, T Kilz, ES Akool, R Müller, J Pfeilschifter Biochemical pharmacology 70 (3), 433-445, 2005 | 15 | 2005 |
| Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway ME Abo-El Fetoh, GK Helal, IG Saleh, M Ewees, M ElShafey, MR Elnagar, ... Naunyn-Schmiedeberg's Archives of Pharmacology 393, 897-908, 2020 | 12 | 2020 |
| Molecular mechanisms of the protective role of wheat germ oil against oxidative stress–induced liver disease ES Akool Dietary interventions in liver disease, 233-238, 2019 | 7 | 2019 |
Bashier osmanUniversity of Khartoum, Faculty of Pharmacy,Department of pharmacology在 uofk.edu 的电子邮件经过验证
