关注
Joseph E. Deweese
Joseph E. Deweese
Professor of Biochemistry, Freed-Hardeman University
在 fhu.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing
JE Deweese, N Osheroff
Nucleic acids research 37 (3), 738-748, 2009
5532009
A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases
BH Schmidt, AB Burgin, JE Deweese, N Osheroff, JM Berger
Nature 465 (7298), 641-644, 2010
1982010
DNA topology and topoisomerases: teaching a “knotty” subject
JE Deweese, MA Osheroff, N Osheroff
Biochemistry and Molecular Biology Education 37 (1), 2-10, 2009
1632009
DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA
S Lee, SR Jung, K Heo, JAW Byl, JE Deweese, N Osheroff, S Hohng
Proceedings of the National Academy of Sciences 109 (8), 2925-2930, 2012
862012
The use of divalent metal ions by type II topoisomerases
JE Deweese, N Osheroff
Metallomics 2 (7), 450-459, 2010
812010
Human topoisomerase IIα uses a two-metal-ion mechanism for DNA cleavage
JE Deweese, AB Burgin, N Osheroff
Nucleic acids research 36 (15), 4883-4893, 2008
722008
Etoposide quinone is a redox-dependent topoisomerase II poison
DA Jacob, SL Mercer, N Osheroff, JE Deweese
Biochemistry 50 (25), 5660-5667, 2011
662011
Etoposide quinone is a covalent poison of human topoisomerase IIβ
NA Smith, JAW Byl, SL Mercer, JE Deweese, N Osheroff
Biochemistry 53 (19), 3229-3236, 2014
572014
Using 3′-bridging phosphorothiolates to isolate the forward DNA cleavage reaction of human topoisomerase IIα
JE Deweese, AB Burgin, N Osheroff
Biochemistry 47 (13), 4129-4140, 2008
502008
Examining the impact of antimicrobial fluoroquinolones on human DNA topoisomerase IIα and IIβ
CA Fief, KG Hoang, SD Phipps, JL Wallace, JE Deweese
ACS omega 4 (2), 4049-4055, 2019
432019
Examination of the Impact of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα
JT Wilson, X Jiang, BC McGill, EC Lisic, JE Deweese
Chemical research in toxicology 29 (4), 649-658, 2016
422016
Catalytic core of human topoisomerase IIα: Insights into enzyme–DNA interactions and drug mechanism
RH Lindsey Jr, MJ Pendleton, RE Ashley, SL Mercer, JE Deweese, ...
Biochemistry 53 (41), 6595-6602, 2014
422014
Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIα
JE Deweese, FP Guengerich, AB Burgin, N Osheroff
Biochemistry 48 (38), 8940-8947, 2009
372009
Coordinating the two protomer active sites of human topoisomerase IIα: nicks as topoisomerase II poisons
JE Deweese, N Osheroff
Biochemistry 48 (7), 1439-1441, 2009
362009
Cu (II) benzoylpyridine thiosemicarbazone complexes: Inhibition of human topoisomerase IIα and activity against breast cancer cells
JD Conner, W Medawala, MT Stephens, WH Morris, JE Deweese, ...
Open Journal of Inorganic Chemistry 6 (2), 146-154, 2016
332016
HU-331 is a catalytic inhibitor of topoisomerase IIα
KM Regal, SL Mercer, JE Deweese
Chemical research in toxicology 27 (12), 2044-2051, 2014
332014
Two-mechanism model for the interaction of etoposide quinone with topoisomerase IIα
EG Gibson, MKM King, SL Mercer, JE Deweese
Chemical research in toxicology 29 (9), 1541-1548, 2016
302016
Inhibitors and poisons of mammalian type II topoisomerases
MB Murphy, SL Mercer, JE Deweese
Advances in molecular toxicology 11, 203-240, 2017
282017
Etoposide catechol is an oxidizable topoisomerase II poison
DA Jacob, EG Gibson, SL Mercer, JE Deweese
Chemical research in toxicology 26 (8), 1156-1158, 2013
262013
Use of divalent metal ions in the DNA cleavage reaction of human type II topoisomerases
JE Deweese, AM Burch, AB Burgin, N Osheroff
Biochemistry 48 (9), 1862-1869, 2009
262009
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