Trapping the dynamic acyl carrier protein in fatty acid biosynthesis C Nguyen, RW Haushalter, DJ Lee, PRL Markwick, J Bruegger, ... Nature 505 (7483), 427-431, 2014 | 274 | 2014 |
Dehydratase-specific probes for fatty acid and polyketide synthases F Ishikawa, RW Haushalter, MD Burkart Journal of the American Chemical Society 134 (2), 769-772, 2012 | 52 | 2012 |
Structural Basis of Protein–Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis A Miyanaga, R Ouchi, F Ishikawa, E Goto, G Tanabe, F Kudo, T Eguchi Journal of the American Chemical Society 140 (25), 7970-7978, 2018 | 48 | 2018 |
Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase F Ishikawa, RW Haushalter, DJ Lee, K Finzel, MD Burkart Journal of the American Chemical Society 135 (24), 8846-8849, 2013 | 44 | 2013 |
Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases S Konno, F Ishikawa, T Suzuki, N Dohmae, MD Burkart, H Kakeya Chemical Communications 51 (12), 2262-2265, 2015 | 38 | 2015 |
Profiling nonribosomal peptide synthetase activities using chemical proteomic probes for adenylation domains F Ishikawa, S Konno, T Suzuki, N Dohmae, H Kakeya ACS chemical biology 10 (9), 1989-1997, 2015 | 26 | 2015 |
Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling S Kasai, S Konno, F Ishikawa, H Kakeya Chemical Communications 51 (87), 15764-15767, 2015 | 26 | 2015 |
A single antibody catalyzes multiple chemical transformations upon replacement of the functionalized small nonprotein components F Ishikawa, T Tsumuraya, I Fujii Journal of the American Chemical Society 131 (2), 456-457, 2009 | 26 | 2009 |
Accurate detection of adenylation domain functions in nonribosomal peptide synthetases by an enzyme-linked immunosorbent assay system using active site-directed probes for … F Ishikawa, K Miyamoto, S Konno, S Kasai, H Kakeya ACS chemical biology 10 (12), 2816-2826, 2015 | 24 | 2015 |
An engineered aryl acid adenylation domain with an enlarged substrate binding pocket F Ishikawa, A Miyanaga, H Kitayama, S Nakamura, I Nakanishi, F Kudo, ... Angewandte Chemie 131 (21), 6980-6984, 2019 | 23 | 2019 |
Specific enrichment of nonribosomal peptide synthetase module by an affinity probe for adenylation domains F Ishikawa, H Kakeya Bioorganic & medicinal chemistry letters 24 (3), 865-869, 2014 | 23 | 2014 |
A 7-dimethylallyl tryptophan synthase from a fungal Neosartorya sp.: Biochemical characterization and structural insight into the regioselective prenylation K Miyamoto, F Ishikawa, S Nakamura, Y Hayashi, I Nakanishi, H Kakeya Bioorganic & medicinal chemistry 22 (8), 2517-2528, 2014 | 20 | 2014 |
Chemoproteomics profiling of surfactin-producing nonribosomal peptide synthetases in living bacterial cells F Ishikawa, S Konno, C Uchida, T Suzuki, K Takashima, N Dohmae, ... Cell Chemical Biology 29 (1), 145-156. e8, 2022 | 18 | 2022 |
Diastereoselective synthesis of salacinol-type α-glucosidase inhibitors F Ishikawa, K Jinno, E Kinouchi, K Ninomiya, S Marumoto, W Xie, ... The Journal of organic chemistry 83 (1), 185-193, 2018 | 18 | 2018 |
In Vitro Investigation of Crosstalk between Fatty Acid and Polyketide Synthases in the Andrimid Biosynthetic Assembly Line F Ishikawa, H Sugimoto, H Kakeya ChemBioChem 17 (22), 2137-2142, 2016 | 17 | 2016 |
Precise Probing of Residue Roles by NRPS Code Swapping: Mutation, Enzymatic Characterization, Modeling, and Substrate Promiscuity of Aryl Acid Adenylation Domains F Ishikawa, M Nohara, S Nakamura, I Nakanishi, G Tanabe Biochemistry 59 (4), 351-363, 2020 | 16 | 2020 |
Total Synthesis of γ-Alkylidenebutenolides, Potent Melanogenesis Inhibitors from Thai Medicinal Plant Melodorum fruticosum G Tanabe, Y Manse, T Ogawa, N Sonoda, S Marumoto, F Ishikawa, ... The Journal of organic chemistry 83 (15), 8250-8264, 2018 | 12 | 2018 |
Total syntheses of the aromatase inhibitors, mammeasins C and D, from Thai medicinal plant Mammea siamensis G Tanabe, N Tsutsui, K Shibatani, S Marumoto, F Ishikawa, K Ninomiya, ... Tetrahedron 73 (30), 4481-4486, 2017 | 12 | 2017 |
Biosynthetic origins of the epoxyquinone skeleton in epoxyquinols A and B K Fujita, F Ishikawa, H Kakeya Journal of natural products 77 (12), 2707-2710, 2014 | 12 | 2014 |
Mutational Biosynthesis of Hitachimycin Analogs Controlled by the β-Amino Acid–Selective Adenylation Enzyme HitB F Kudo, S Takahashi, A Miyanaga, Y Nakazawa, K Nishino, Y Hayakawa, ... ACS Chemical Biology 16 (3), 539-547, 2021 | 11 | 2021 |